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Deficiency of the sphingosine-1-phosphate (S1P) transporter Mfsd2b protects the heart against hypertension-induced cardiac remodeling by suppressing the L-type-Ca2+ channel.
Duse DA, Schröder NH, Srivastava T, Benkhoff M, Vogt J, Nowak MK, Funk F, Semleit N, Wollnitzke P, Erkens R, Kötter S, Meuth SG, Keul P, Santos W, Polzin A, Kelm M, Krüger M, Schmitt J, Levkau B. Duse DA, et al. Basic Res Cardiol. 2024 Oct;119(5):853-868. doi: 10.1007/s00395-024-01073-x. Epub 2024 Aug 7. Basic Res Cardiol. 2024. PMID: 39110173 Free PMC article.
Plasma Proteome Analysis Identifies Vascular Endothelial Growth Factor Receptor 1 as a Prognostic Biomarker in Cardiogenic Shock.
Jung C, Lang A, Duse DA, Bruno RR, Pöss J, Wolff G, Ceglarek U, Zeymer U, Fuernau G, Zweck E, Desch S, Freund A, Isermann B, Pfeiler S, Wernly B, Kelm M, Thiele H, Gerdes N. Jung C, et al. Among authors: duse da. Circ Heart Fail. 2025 Dec;18(12):e012890. doi: 10.1161/CIRCHEARTFAILURE.125.012890. Epub 2025 Oct 1. Circ Heart Fail. 2025. PMID: 41031405 Clinical Trial.
Inhibition of proline-rich tyrosine kinase 2 restores cardioprotection by remote ischaemic preconditioning in type 2 diabetes.
Erkens R, Duse DA, Brum A, Chadt A, Becher S, Siragusa M, Quast C, Müssig J, Roden M, Cortese-Krott M, Ibáñez B, Lammert E, Fleming I, Jung C, Al-Hasani H, Heusch G, Kelm M. Erkens R, et al. Among authors: duse da. Br J Pharmacol. 2024 Nov;181(21):4174-4194. doi: 10.1111/bph.16483. Epub 2024 Jul 2. Br J Pharmacol. 2024. PMID: 38956895 Free article.
14 results