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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1982 1
2000 1
2002 2
2003 1
2004 2
2007 2
2009 1
2013 1
2014 2
2015 1
2016 1
2017 2
2019 3
2020 2
2021 2
2024 0

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23 results

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Page 1
Embracing model-based designs for dose-finding trials.
Love SB, Brown S, Weir CJ, Harbron C, Yap C, Gaschler-Markefski B, Matcham J, Caffrey L, McKevitt C, Clive S, Craddock C, Spicer J, Cornelius V. Love SB, et al. Br J Cancer. 2017 Jul 25;117(3):332-339. doi: 10.1038/bjc.2017.186. Epub 2017 Jun 29. Br J Cancer. 2017. PMID: 28664918 Free PMC article. Review.
The most prominent barriers to implementation of a model-based design were lack of suitable training, chief investigators' preference for algorithm-based designs (e.g., 3+3), and limited resources for study design before funding. We use a real-world example to illustrate h …
The most prominent barriers to implementation of a model-based design were lack of suitable training, chief investigators' preference for al …
Factors shaping the delivery of acute inpatient stroke therapy: a narrative synthesis.
Taylor E, McKevitt C, Jones F. Taylor E, et al. J Rehabil Med. 2015 Feb;47(2):107-19. doi: 10.2340/16501977-1918. J Rehabil Med. 2015. PMID: 25437308 Free article. Review.
OBJECTIVE: To investigate factors shaping the delivery of acute inpatient stroke therapy (i.e. occupational therapy, physiotherapy, and speech and language therapy). DATA SOURCES: A systematic search using electronic databases: AMED, CINAHL, Medline, Web of Knowledge and E …
OBJECTIVE: To investigate factors shaping the delivery of acute inpatient stroke therapy (i.e. occupational therapy, physiotherapy, a …
The protein network of bacterial motility.
Rajagopala SV, Titz B, Goll J, Parrish JR, Wohlbold K, McKevitt MT, Palzkill T, Mori H, Finley RL Jr, Uetz P. Rajagopala SV, et al. Mol Syst Biol. 2007;3:128. doi: 10.1038/msb4100166. Epub 2007 Jul 31. Mol Syst Biol. 2007. PMID: 17667950 Free PMC article.
Comparing our interaction data with motility phenotypes from E. coli, Bacillus subtilis, and Helicobacter pylori, we found 23 hitherto uncharacterized proteins involved in motility. ...
Comparing our interaction data with motility phenotypes from E. coli, Bacillus subtilis, and Helicobacter pylori, we found 23 hithert …
BAC library of T. pallidum DNA in E. coli.
Smajs D, McKevitt M, Wang L, Howell JK, Norris SJ, Palzkill T, Weinstock GM. Smajs D, et al. Genome Res. 2002 Mar;12(3):515-22. doi: 10.1101/gr.207302. Genome Res. 2002. PMID: 11875041 Free PMC article.
Of mapped clones, 19 were selected to represent the minimal set of E. coli BAC clones covering 1026 of the total 1040 (98.7%) predicted T. pallidum ORFs. Using this minimal set of clones, at least 12 T. pallidum proteins were shown to react with pooled sera from rabbits im …
Of mapped clones, 19 were selected to represent the minimal set of E. coli BAC clones covering 1026 of the total 1040 (98.7%) predict …
Strategies for In Vivo Screening and Mitigation of Hepatotoxicity Associated with Antisense Drugs.
Kamola PJ, Maratou K, Wilson PA, Rush K, Mullaney T, McKevitt T, Evans P, Ridings J, Chowdhury P, Roulois A, Fairchild A, McCawley S, Cartwright K, Gooderham NJ, Gant TW, Moores K, Hughes SA, Edbrooke MR, Clark K, Parry JD. Kamola PJ, et al. Mol Ther Nucleic Acids. 2017 Sep 15;8:383-394. doi: 10.1016/j.omtn.2017.07.003. Epub 2017 Jul 8. Mol Ther Nucleic Acids. 2017. PMID: 28918038 Free PMC article.
Unfortunately, their therapeutic application, particularly that of the more potent chemistries (e.g., locked-nucleic-acid-containing gapmers), has been hampered by their frequent hepatoxicity, which could be driven by hybridization-mediated interactions. ...A single-dose ( …
Unfortunately, their therapeutic application, particularly that of the more potent chemistries (e.g., locked-nucleic-acid-containing …
What underlies the difference between self-reported health and disability after stroke? A qualitative study in the UK.
Mavaddat N, Sadler E, Lim L, Williams K, Warburton E, Kinmonth AL, Mckevitt C, Mant J. Mavaddat N, et al. BMC Neurol. 2021 Aug 13;21(1):315. doi: 10.1186/s12883-021-02338-x. BMC Neurol. 2021. PMID: 34388983 Free PMC article.
Fifteen stroke survivors purposively sampled from the clinic who had discordant self-rated health and levels of disability i.e. reported health as 'excellent' or 'good' despite significant physical disability (eight), or as 'fair' or 'poor' despite minimal disability (seve …
Fifteen stroke survivors purposively sampled from the clinic who had discordant self-rated health and levels of disability i.e. repor …
Antimicrobial prophylaxis of recurrent urinary tract infections: a double-blind, placebo-controlled trial.
Stamm WE, Counts GW, Wagner KF, Martin D, Gregory D, McKevitt M, Turck M, Holmes KK. Stamm WE, et al. Ann Intern Med. 1980 Jun;92(6):770-5. doi: 10.7326/0003-4819-92-6-770. Ann Intern Med. 1980. PMID: 6992677 Clinical Trial.
Emergence of trimethoprim-resistant Escherichia coli was rare, but non-E. coli infections occurred more often after prophylaxis (P less than 0.05). Prophylaxis with these drugs is effective, well tolerated, and did not produce emergence of resistant E. coli but may …
Emergence of trimethoprim-resistant Escherichia coli was rare, but non-E. coli infections occurred more often after prophylaxis (P le …
Health care follow-up after stroke: opportunities for secondary prevention.
Redfern J, McKevitt C, Rudd AG, Wolfe CD. Redfern J, et al. Fam Pract. 2002 Aug;19(4):378-82. doi: 10.1093/fampra/19.4.378. Fam Pract. 2002. PMID: 12110559
Doctor-led follow-up was related to treatment of physiological risk factors (e.g. 73% of hypertensive patients who had seen a GP were treated compared with 59% who had seen only a hospital specialist and 47% who had seen neither). ...
Doctor-led follow-up was related to treatment of physiological risk factors (e.g. 73% of hypertensive patients who had seen a GP were …
23 results