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43 results

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Page 1
Did you mean E. linquist (4 results)?
Commentary on "Abiraterone in metastatic prostate cancer without previous chemotherapy." Ryan CJ, Smith MR, de Bono JS, Molina A, Logothetis CJ, de Souza P, Fizazi K, Mainwaring P, Piulats JM, Ng S, Carles J, Mulders PF, Basch E, Small EJ, Saad F, Schrijvers D, Van Poppel H, Mukherjee SD, Suttmann H, Gerritsen WR, Flaig TW, George DJ, Yu EY, Efstathiou E, Pantuck A, Winquist E, Higano CS, Taplin ME, Park Y, Kheoh T, Griffin T, Scher HI, Rathkopf DE; COU-AA-302 Investigators, Genitourinary Medical Oncology Program, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA. N Engl J Med 2013;368(2):138-48 [Epub 2012 Dec 10]; N Engl J Med 2013;368(6):584.
Trump DL. Trump DL. Urol Oncol. 2013 Nov;31(8):1846. doi: 10.1016/j.urolonc.2013.08.012. Urol Oncol. 2013. PMID: 24210085
Real-world assessment of clinical outcomes of first-line treatment in metastatic papillary renal cell carcinoma.
De Vries-Brilland M, Hamilou Z, Ghosh S, Heng DYC, Wood LA, Basappa NS, Kollmannsberger CK, Graham J, Bhindi B, Finelli A, Bjarnason GA, Bosse D, Pouliot F, Castonguay V, Breau RH, Saleh RR, Winquist E, Lalani AA, Soulières D. De Vries-Brilland M, et al. Oncologist. 2025 Sep 1;30(9):oyaf240. doi: 10.1093/oncolo/oyaf240. Oncologist. 2025. PMID: 40757924 Free PMC article.
Prospective multicenter study of ctDNA versus tumor tissue guiding FGFR-targeted therapy in metastatic urothelial cancer.
Müller DC, Murtha AJ, Bacon JVW, Stephenson M, Wells C, Vasquez-Rios C, Rostin K, Rebane L, Schönlau E, Nikkola J, Alimohamed N, Basappa NS, Finch D, Ko JJ, Lavoie JM, Nappi L, Noonan K, Ong M, Ozgun G, Parimi S, Soleimani M, Sridhar SS, Toren P, Winquist E, Bernales CQ, Koudjanian M, Atwal J, Fung E, Khan L, Eigl B, Othman D, Bismar TA, Wang G, Merza R, Papadakis AI, Spatz A, Kollmannsberger C, Maurice-Dror C, Annala M, Chi KN, Vandekerkhove G, Wyatt AW, Eigl BJ. Müller DC, et al. Nat Commun. 2026 Feb 27;17(1):3263. doi: 10.1038/s41467-026-69927-7. Nat Commun. 2026. PMID: 41760649 Free PMC article.
The fall and rise of pharmacology--(re-)defining the discipline?
Winquist RJ, Mullane K, Williams M. Winquist RJ, et al. Biochem Pharmacol. 2014 Jan 1;87(1):4-24. doi: 10.1016/j.bcp.2013.09.011. Epub 2013 Sep 23. Biochem Pharmacol. 2014. PMID: 24070656 Review.
However, concerns regarding the disconnect between basic research efforts and the approval of new drugs to treat 21st Century disease tsunamis, e.g., neurodegeneration, metabolic syndrome, etc. has led to the reemergence of pharmacology, its rise, often in the semantic gui …
However, concerns regarding the disconnect between basic research efforts and the approval of new drugs to treat 21st Century disease tsunam …
Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).
Lippman SM, Klein EA, Goodman PJ, Lucia MS, Thompson IM, Ford LG, Parnes HL, Minasian LM, Gaziano JM, Hartline JA, Parsons JK, Bearden JD 3rd, Crawford ED, Goodman GE, Claudio J, Winquist E, Cook ED, Karp DD, Walther P, Lieber MM, Kristal AR, Darke AK, Arnold KB, Ganz PA, Santella RM, Albanes D, Taylor PR, Probstfield JL, Jagpal TJ, Crowley JJ, Meyskens FL Jr, Baker LH, Coltman CA Jr. Lippman SM, et al. JAMA. 2009 Jan 7;301(1):39-51. doi: 10.1001/jama.2008.864. Epub 2008 Dec 9. JAMA. 2009. PMID: 19066370 Free PMC article. Clinical Trial.
DESIGN, SETTING, AND PARTICIPANTS: A randomized, placebo-controlled trial (Selenium and Vitamin E Cancer Prevention Trial [SELECT]) of 35,533 men from 427 participating sites in the United States, Canada, and Puerto Rico randomly assigned to 4 groups (selenium, vitamin …
DESIGN, SETTING, AND PARTICIPANTS: A randomized, placebo-controlled trial (Selenium and Vitamin E Cancer Prevention Trial [SELECT]) o …
Durvalumab and tremelimumab in patients with advanced rare cancer: a multi-centre, non-blinded, open-label phase II basket trial.
Gupta AA, Tinker A, Jonker D, Jamal R, Hirte H, Winquist EW, Chu Q, Kollmannsberger C, Wong R, Alcindor T, Nielsen TO, Tsao M, Cottrell TR, Provencher D, Hilton J, Krzyżanowska MK, Elser C, Hotte S, Sederias J, Zhang S, Tu W, Dancey J. Gupta AA, et al. EClinicalMedicine. 2024 Dec 10;79:102991. doi: 10.1016/j.eclinm.2024.102991. eCollection 2025 Jan. EClinicalMedicine. 2024. PMID: 39737219 Free PMC article.
Valproate reverses mania-like behaviors in mice via preferential targeting of HDAC2.
Logan RW, Ozburn AR, Arey RN, Ketchesin KD, Winquist A, Crain A, Tobe BTD, Becker-Krail D, Jarpe MB, Xue X, Zong W, Huo Z, Parekh PK, Zhu X, Fitzgerald E, Zhang H, Oliver-Smith J, DePoy LM, Hildebrand MA, Snyder EY, Tseng GC, McClung CA. Logan RW, et al. Mol Psychiatry. 2021 Aug;26(8):4066-4084. doi: 10.1038/s41380-020-00958-2. Epub 2020 Nov 24. Mol Psychiatry. 2021. PMID: 33235333 Free PMC article.
We find compounds that inhibit histone deacetylase proteins (HDACs) are effective in normalizing manic-like behavior, and that class I HDACs (e.g., HDAC1 and HDAC2) are most important in this response. Using an RNAi approach, we find that HDAC2, but not HDAC1, inhibition i …
We find compounds that inhibit histone deacetylase proteins (HDACs) are effective in normalizing manic-like behavior, and that class I HDACs …
43 results