Search Page

1

Cite

Share

Inflammation Induced by Platelet-Activating Viperid Snake Venoms: Perspectives on Thromboinflammation.

Teixeira C, Fernandes CM, Leiguez E, Chudzinski-Tavassi AM. Teixeira C, et al. Among authors: leiguez e. Front Immunol. 2019 Sep 4;10:2082. doi: 10.3389/fimmu.2019.02082. eCollection 2019. Front Immunol. 2019. PMID: 31572356 Free PMC article. Review.

Cite

Share

2

Cite

Share

Inflammatory Effects of Bothrops Phospholipases A₂: Mechanisms Involved in Biosynthesis of Lipid Mediators and Lipid Accumulation.

Moreira V, Leiguez E, Janovits PM, Maia-Marques R, Fernandes CM, Teixeira C. Moreira V, et al. Among authors: leiguez e. Toxins (Basel). 2021 Dec 4;13(12):868. doi: 10.3390/toxins13120868. Toxins (Basel). 2021. PMID: 34941706 Free PMC article. Review.

Cite

Share

3

Cite

Share

A Metalloproteinase Induces an Inflammatory Response in Preadipocytes with the Activation of COX Signalling Pathways and Participation of Endogenous Phospholipases A₂.

Janovits PM, Leiguez E, Portas V, Teixeira C. Janovits PM, et al. Among authors: leiguez e. Biomolecules. 2021 Jun 22;11(7):921. doi: 10.3390/biom11070921. Biomolecules. 2021. PMID: 34206390 Free PMC article.

Cite

Share

4

Cite

Share

Evaluation of pro-inflammatory events induced by Bothrops alternatus snake venom.

Echeverría S, Leiguez E, Guijas C, do Nascimento NG, Acosta O, Teixeira C, Leiva LC, Rodríguez JP. Echeverría S, et al. Among authors: leiguez e. Chem Biol Interact. 2018 Feb 1;281:24-31. doi: 10.1016/j.cbi.2017.12.022. Epub 2017 Dec 14. Chem Biol Interact. 2018. PMID: 29248447

Cite

Share

5

Cite

Share

A Representative GIIA Phospholipase A₂ Activates Preadipocytes to Produce Inflammatory Mediators Implicated in Obesity Development.

Leiguez E, Motta P, Maia Marques R, Lomonte B, Sampaio SV, Teixeira C. Leiguez E, et al. Biomolecules. 2020 Nov 24;10(12):1593. doi: 10.3390/biom10121593. Biomolecules. 2020. PMID: 33255269 Free PMC article.

Cite

Share

6

Cite

Share

A representative metalloprotease induces PGE₂ synthesis in fibroblast-like synoviocytes via the NF-κB/COX-2 pathway with amplification by IL-1β and the EP4 receptor.

Viana MN, Leiguez E, Gutiérrez JM, Rucavado A, Markus RP, Marçola M, Teixeira C, Fernandes CM. Viana MN, et al. Among authors: leiguez e. Sci Rep. 2020 Feb 24;10(1):3269. doi: 10.1038/s41598-020-59095-z. Sci Rep. 2020. PMID: 32094439 Free PMC article.

Cite

Share

7

Cite

Share

A Lipidomic Perspective of the Action of Group IIA Secreted Phospholipase A₂ on Human Monocytes: Lipid Droplet Biogenesis and Activation of Cytosolic Phospholipase A₂α.

Rodríguez JP, Leiguez E, Guijas C, Lomonte B, Gutiérrez JM, Teixeira C, Balboa MA, Balsinde J. Rodríguez JP, et al. Among authors: leiguez e. Biomolecules. 2020 Jun 10;10(6):891. doi: 10.3390/biom10060891. Biomolecules. 2020. PMID: 32532115 Free PMC article.

Cite

Share

8

Cite

Share

A Secreted Phospholipase A₂ Induces Formation of Smooth Muscle Foam Cells Which Transdifferentiate to Macrophage-Like State.

Giannotti KC, Weinert S, Viana MN, Leiguez E, Araujo TLS, Laurindo FRM, Lomonte B, Braun-Dullaeus R, Teixeira C. Giannotti KC, et al. Among authors: leiguez e. Molecules. 2019 Sep 6;24(18):3244. doi: 10.3390/molecules24183244. Molecules. 2019. PMID: 31489892 Free PMC article.

Cite

Share

9

Cite

Share

A Snake Venom-Secreted Phospholipase A₂ Induces Foam Cell Formation Depending on the Activation of Factors Involved in Lipid Homeostasis.

Leiguez E, Giannotti KC, Viana MDN, Matsubara MH, Fernandes CM, Gutiérrez JM, Lomonte B, Teixeira C. Leiguez E, et al. Mediators Inflamm. 2018 Jun 14;2018:2547918. doi: 10.1155/2018/2547918. eCollection 2018. Mediators Inflamm. 2018. PMID: 30013451 Free PMC article.

Cite

Share

10

Cite

Share

A snake venom group IIA PLA₂ with immunomodulatory activity induces formation of lipid droplets containing 15-d-PGJ₂ in macrophages.

Giannotti KC, Leiguez E, Carvalho AEZ, Nascimento NG, Matsubara MH, Fortes-Dias CL, Moreira V, Teixeira C. Giannotti KC, et al. Among authors: leiguez e. Sci Rep. 2017 Jun 22;7(1):4098. doi: 10.1038/s41598-017-04498-8. Sci Rep. 2017. PMID: 28642580 Free PMC article.

Cite

Share