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Page 1
Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial.
Rovin BH, Barratt J, Heerspink HJL, Alpers CE, Bieler S, Chae DW, Diva UA, Floege J, Gesualdo L, Inrig JK, Kohan DE, Komers R, Kooienga LA, Lafayette R, Maes B, Małecki R, Mercer A, Noronha IL, Oh SW, Peh CA, Praga M, Preciado P, Radhakrishnan J, Rheault MN, Rote WE, Tang SCW, Tesar V, Trachtman H, Trimarchi H, Tumlin JA, Wong MG, Perkovic V; DUPRO steering committee and PROTECT Investigators. Rovin BH, et al. Lancet. 2023 Dec 2;402(10417):2077-2090. doi: 10.1016/S0140-6736(23)02302-4. Epub 2023 Nov 3. Lancet. 2023. PMID: 37931634 Clinical Trial.
Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial.
Heerspink HJL, Radhakrishnan J, Alpers CE, Barratt J, Bieler S, Diva U, Inrig J, Komers R, Mercer A, Noronha IL, Rheault MN, Rote W, Rovin B, Trachtman H, Trimarchi H, Wong MG, Perkovic V; PROTECT Investigators. Heerspink HJL, et al. Lancet. 2023 May 13;401(10388):1584-1594. doi: 10.1016/S0140-6736(23)00569-X. Epub 2023 Apr 1. Lancet. 2023. PMID: 37015244 Clinical Trial.
How Stem and Progenitor Cells Can Affect Renal Diseases.
Montenegro F, Giannuzzi F, Picerno A, Cicirelli A, Stea ED, Di Leo V, Sallustio F. Montenegro F, et al. Among authors: stea ed. Cells. 2024 Aug 30;13(17):1460. doi: 10.3390/cells13171460. Cells. 2024. PMID: 39273032 Free PMC article. Review.
What Is Hidden in Patients with Unknown Nephropathy? Genetic Screening Could Be the Missing Link in Kidney Transplantation Diagnosis and Management.
Mitrotti A, Di Bari I, Giliberti M, Franzin R, Conserva F, Chiusolo A, Gigante M, Accetturo M, Cafiero C, Ricciato L, Stea ED, Forleo C, Gallone A, Rossini M, Fiorentino M, Castellano G, Pontrelli P, Gesualdo L. Mitrotti A, et al. Among authors: stea ed. Int J Mol Sci. 2024 Jan 24;25(3):1436. doi: 10.3390/ijms25031436. Int J Mol Sci. 2024. PMID: 38338714 Free PMC article.
Multidisciplinary consensus on the diagnosis and management of patients with atypical Hemolytic Uremic Syndrome (complement-mediated TMA): recommendations from Italian scientific societies, patient associations and regulators.
Stea ED, Pugliano M, Gualtierotti R, Mazzucato M, Santangelo L, Annicchiarico G, Berardelli A, Bianchi S, Bogliolo L, Chiandotto P, Cirino G, Iaco F, Rosa S, Dentali F, Facchin P, Favalli EG, Fiorin F, Giarratano A, Laterza C, Macrì F, Mancuso M, Padovani A, Pasini A, Scopinaro AM, Sebastiani GD, Sesti G, Susi B, Torsello A, Vezzoni C, Zanlari L, Gesualdo L, Luca A. Stea ED, et al. Pharmacol Res. 2025 Apr 7:107714. doi: 10.1016/j.phrs.2025.107714. Online ahead of print. Pharmacol Res. 2025. PMID: 40204022 Free article. Review.
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