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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 6
1953 1
1954 1
1955 4
1956 1
1957 2
1958 1
1959 2
1961 5
1962 6
1963 160
1964 283
1965 123
1966 21
1967 25
1968 34
1969 18
1970 19
1971 27
1972 19
1973 29
1974 25
1975 47
1976 41
1977 54
1978 54
1979 72
1980 54
1981 51
1982 61
1983 61
1984 71
1985 71
1986 76
1987 81
1988 101
1989 119
1990 106
1991 151
1992 108
1993 112
1994 101
1995 144
1996 139
1997 106
1998 128
1999 143
2000 221
2001 245
2002 265
2003 271
2004 309
2005 322
2006 355
2007 351
2008 551
2009 604
2010 632
2011 698
2012 747
2013 657
2014 634
2015 671
2016 616
2017 668
2018 686
2019 691
2020 721
2021 154
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13,206 results
Results by year
Filters applied: . Clear all The following term was not found in PubMed: Macharm
Page 1
The growing relevance of biological ene reactions.
Jensen AW, Mohanty DK, Dilling WL. Jensen AW, et al. Bioorg Med Chem. 2019 Mar 1;27(5):686-691. doi: 10.1016/j.bmc.2019.01.020. Epub 2019 Jan 24. Bioorg Med Chem. 2019. PMID: 30709643 Review.
The ene reaction involves the addition of an 'ene' to an 'enophile.' The retro-ene reaction is the reverse of the ene reaction. In recent years various biological molecules have been found to form covalent intermediates (ene-adducts) that might …
The ene reaction involves the addition of an 'ene' to an 'enophile.' The retro-ene reaction is the reverse of the en
5-Ene-4-thiazolidinones - An efficient tool in medicinal chemistry.
Kaminskyy D, Kryshchyshyn A, Lesyk R. Kaminskyy D, et al. Eur J Med Chem. 2017 Nov 10;140:542-594. doi: 10.1016/j.ejmech.2017.09.031. Epub 2017 Sep 20. Eur J Med Chem. 2017. PMID: 28987611 Free PMC article. Review.
Nevertheless, the crucial impact of the presence/nature of C5 substituent (namely 5-ene) on the pharmacological effects of 5-ene-4-thiazolidinones was confirmed by the numerous listed findings from the original articles. ...Moreover, the utilization of 5-ene- …
Nevertheless, the crucial impact of the presence/nature of C5 substituent (namely 5-ene) on the pharmacological effects of 5-ene
Ene cyclization reaction in heterocycle synthesis.
Saha P, Saikia AK. Saha P, et al. Org Biomol Chem. 2018 Apr 25;16(16):2820-2840. doi: 10.1039/c8ob00429c. Org Biomol Chem. 2018. PMID: 29594296 Review.
The ene cyclization has evolved to become an indispensable tool for the synthesis of various ring size heterocyclic compounds. ...Moreover, the ease of regio- and stereoselectivity of ene cyclization has led to the development of new types of heterocyclic compounds. …
The ene cyclization has evolved to become an indispensable tool for the synthesis of various ring size heterocyclic compounds. ...Mor …
Applications of Thiol-Ene Chemistry for Peptide Science.
Nolan MD, Scanlan EM. Nolan MD, et al. Front Chem. 2020 Nov 12;8:583272. doi: 10.3389/fchem.2020.583272. eCollection 2020. Front Chem. 2020. PMID: 33282831 Free PMC article. Review.
The thiol-ene reaction offers a number of advantages in this area, primarily those characteristic of "click" reactions. ...This review will cover the range of applications of the radical-mediated thiol-ene reaction in peptide and protein science....
The thiol-ene reaction offers a number of advantages in this area, primarily those characteristic of "click" reactions. ...This revie …
Metal-free photocatalytic thiol-ene/thiol-yne reactions.
Kaur S, Zhao G, Busch E, Wang T. Kaur S, et al. Org Biomol Chem. 2019 Feb 13;17(7):1955-1961. doi: 10.1039/c8ob02313a. Org Biomol Chem. 2019. PMID: 30334562
The organic photocatalyst (9-mesityl-10-methylacridinum tetrafluoroborate) in the presence of visible light is used to initiate thiol-ene and thiol-yne reactions. Thiyl radicals are generated upon quenching the photoexcited catalyst with a range of thiols. The highlighted …
The organic photocatalyst (9-mesityl-10-methylacridinum tetrafluoroborate) in the presence of visible light is used to initiate thiol-ene
Tunable and Magnetic Thiol-ene Micropillar Arrays.
Al-Azawi A, Cenev Z, Tupasela T, Peng B, Ikkala O, Zhou Q, Jokinen V, Franssila S, Ras RHA. Al-Azawi A, et al. Macromol Rapid Commun. 2020 Jan;41(2):e1900522. doi: 10.1002/marc.201900522. Epub 2019 Nov 28. Macromol Rapid Commun. 2020. PMID: 31778287
Inspired by cilia structure in the respiratory pathway, magnetically responsive periodic arrays of flexible and magnetic thiol-ene micropillars are fabricated. Omnidirectional collective bending of the pillar array in magnetic field is shown. Local non-contact actuation of …
Inspired by cilia structure in the respiratory pathway, magnetically responsive periodic arrays of flexible and magnetic thiol-ene mi …
Androst-5-ene-3beta,7alpha/beta,17beta-triols, their plasma levels and dependence on the hypothalamic-pituitary-adrenal axis.
Stárka L, Hill M, Kolatorova L, Dušková M. Stárka L, et al. Steroids. 2018 Jun;134:88-95. doi: 10.1016/j.steroids.2018.02.005. Epub 2018 Feb 23. Steroids. 2018. PMID: 29477344
Androst-5-ene-triols are metabolites of dehydroepiandrosterone, the most abundant steroid hormone in human circulation. ...Here we provide some data on androst-5-ene-3beta,7alpha/beta,17beta-triol concentrations under various conditions in men and women....
Androst-5-ene-triols are metabolites of dehydroepiandrosterone, the most abundant steroid hormone in human circulation. ...Here we pr …
A highly ordered, nonprotective MALAT1 ENE structure is adopted prior to triplex formation.
Yonkunas MJ, Baird NJ. Yonkunas MJ, et al. RNA. 2019 Aug;25(8):975-984. doi: 10.1261/rna.069906.118. Epub 2019 May 21. RNA. 2019. PMID: 31113838 Free PMC article.
Formation of an ENE triple helix is required to support transcript accumulation, leading to persistent oncogenic activity of MALAT1 in multiple cancer types. ...We hypothesize that disruption of the maturation or folding process may be a viable mechanism of inhibition. To …
Formation of an ENE triple helix is required to support transcript accumulation, leading to persistent oncogenic activity of MALAT1 i …
Rhodium-Catalyzed [4+2+1] Cycloaddition of In Situ Generated Ene/Yne-Ene-Allenes and CO.
Tian ZY, Cui Q, Liu CH, Yu ZX. Tian ZY, et al. Angew Chem Int Ed Engl. 2018 Nov 19;57(47):15544-15548. doi: 10.1002/anie.201805908. Epub 2018 Oct 25. Angew Chem Int Ed Engl. 2018. PMID: 30102822
Reported herein is the first rhodium-catalyzed [4+2+1] cycloaddition of in situ generated ene/yne-ene-allenes and CO to synthesize challenging seven-membered carbocycles fused with five-membered rings. This reaction is designed based on the 1,3-acyloxy migration of …
Reported herein is the first rhodium-catalyzed [4+2+1] cycloaddition of in situ generated ene/yne-ene-allenes and CO to synthe …
Crystal structure of 1,2-di-benzoyl-ace-naphthyl-ene.
Greenberg FH, Nazarenko AY. Greenberg FH, et al. Acta Crystallogr E Crystallogr Commun. 2015 Jun 13;71(Pt 7):o487-8. doi: 10.1107/S2056989015011160. eCollection 2015 Jul 1. Acta Crystallogr E Crystallogr Commun. 2015. PMID: 26279922 Free PMC article.
Both carbonyl groups are oriented towards the same side of the planar ace-naphthyl-ene. The angles between the flat ace-naphthyl-ene group and the benzoyl groups are 62.6 (1) and 57.8 (1). Because rotation of the benzoyl groups is sterically hindered, we expect that …
Both carbonyl groups are oriented towards the same side of the planar ace-naphthyl-ene. The angles between the flat ace-naphthyl-e
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