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Page 1
Showing results for unique mu
Search for Enrique Mu instead (2 results)
Transposable Phage Mu.
Harshey RM. Harshey RM. Microbiol Spectr. 2014 Oct;2(5):10.1128/microbiolspec.MDNA3-0007-2014. doi: 10.1128/microbiolspec.MDNA3-0007-2014. Microbiol Spectr. 2014. PMID: 26104374 Free PMC article. Review.
The deduced phosphotransfer mechanism involves in-line orientation of metal ion-activated hydroxyl groups for nucleophilic attack on reactive diester bonds, a mechanism that appears to be used by all transposable elements examined to date. A crystal structure of the Mu tra …
The deduced phosphotransfer mechanism involves in-line orientation of metal ion-activated hydroxyl groups for nucleophilic attack on reactiv …
Structural basis of mu-opioid receptor targeting by a nanobody antagonist.
Yu J, Kumar A, Zhang X, Martin C, Van Holsbeeck K, Raia P, Koehl A, Laeremans T, Steyaert J, Manglik A, Ballet S, Boland A, Stoeber M. Yu J, et al. Nat Commun. 2024 Oct 9;15(1):8687. doi: 10.1038/s41467-024-52947-6. Nat Commun. 2024. PMID: 39384768 Free PMC article.
The mu-opioid receptor (muOR), a prototypical G protein-coupled receptor (GPCR), is the target of opioid analgesics such as morphine and fentanyl. ...The work illustrates the potential of nanobodies to uniquely engage with GPCRs and describes lower molecular weight …
The mu-opioid receptor (muOR), a prototypical G protein-coupled receptor (GPCR), is the target of opioid analgesics such as morphine …
Structural Basis of mu-Opioid Receptor-Targeting by a Nanobody Antagonist.
Yu J, Kumar A, Zhang X, Martin C, Raia P, Koehl A, Laeremans T, Steyaert J, Manglik A, Ballet S, Boland A, Stoeber M. Yu J, et al. bioRxiv [Preprint]. 2023 Dec 7:2023.12.06.570395. doi: 10.1101/2023.12.06.570395. bioRxiv. 2023. Update in: Nat Commun. 2024 Oct 9;15(1):8687. doi: 10.1038/s41467-024-52947-6. PMID: 38106026 Free PMC article. Updated. Preprint.
The mu-opioid receptor (muOR), a prototypical member of the G protein-coupled receptor (GPCR) family, is the molecular target of opioid analgesics such as morphine and fentanyl. ...The work illustrates the potential of nanobodies to uniquely engage with GPCRs and de …
The mu-opioid receptor (muOR), a prototypical member of the G protein-coupled receptor (GPCR) family, is the molecular target of opio …
DNA polymerase mu: An inflexible scaffold for substrate flexibility.
Kaminski AM, Bebenek K, Pedersen LC, Kunkel TA. Kaminski AM, et al. DNA Repair (Amst). 2020 Sep;93:102932. doi: 10.1016/j.dnarep.2020.102932. DNA Repair (Amst). 2020. PMID: 33087269 Free PMC article. Review.
DNA polymerase mu is a Family X member that participates in repair of DNA double strand breaks (DSBs) by non-homologous end joining. ...Here we review the unique properties of Pol mu that allow it to productively engage such a highly unstable substrate to gen …
DNA polymerase mu is a Family X member that participates in repair of DNA double strand breaks (DSBs) by non-homologous end joining. …
Remifentanil.
Patel SS, Spencer CM. Patel SS, et al. Drugs. 1996 Sep;52(3):417-27; discussion 428. doi: 10.2165/00003495-199652030-00009. Drugs. 1996. PMID: 8875131 Review.
Remifentanil is a new selective mu opioid receptor agonist of higher potency than alfentanil, with pharmacological effects that essentially parallel those of alfentanil and other opioids in this class. ...Therefore, appropriate postoperative analgesia, when necessary, shou …
Remifentanil is a new selective mu opioid receptor agonist of higher potency than alfentanil, with pharmacological effects that essen …
Poly[[bis-(mu(4)-acetato-kappa(4) O:O:O':O')tetra-kis-(mu(3)-acetato-kappa(3) O:O:O')bis-(mu(2)-acetato-kappa(2) O:O')bis-(mu(3)-hydroxido)penta-nickel(II)] 2.60-hydrate].
Pfeiffer M, Stöger B, Weil M. Pfeiffer M, et al. IUCrdata. 2025 Feb 7;10(Pt 2):x250082. doi: 10.1107/S2414314625000823. eCollection 2025 Feb. IUCrdata. 2025. PMID: 40092361 Free PMC article.
Its asymmetric unit comprises half of the formula unit, with one of the three unique Ni(II) cations situated at an inversion centre. The Ni(II) atoms are in octa-hedral coordination environments by O atoms of the acetato ligands and by the basic OH group. The different kin …
Its asymmetric unit comprises half of the formula unit, with one of the three unique Ni(II) cations situated at an inversion centre. …
Multiple mu opiate receptors.
Pasternak GW, Wood PJ. Pasternak GW, et al. Life Sci. 1986 May 26;38(21):1889-98. doi: 10.1016/0024-3205(86)90217-1. Life Sci. 1986. PMID: 2872563 Free article. Review.
In addition to morphine-selective mu 2 and enkephalin-preferring delta sites, recent evidence supports the presence within the central nervous system of a common site with very high affinity for both enkephalins and opiates termed the mu 1 site. This concept of a co …
In addition to morphine-selective mu 2 and enkephalin-preferring delta sites, recent evidence supports the presence within the centra …
Phosphorylation of unique C-terminal sites of the mu-opioid receptor variants 1B2 and 1C1 influences their Gs association following chronic morphine.
Chakrabarti S, Liu NJ, Gintzler AR. Chakrabarti S, et al. J Neurochem. 2020 Feb;152(4):449-467. doi: 10.1111/jnc.14863. Epub 2019 Oct 20. J Neurochem. 2020. PMID: 31479519 Free PMC article.
We recently demonstrated in rat spinal cord that a regimen of escalating doses of systemic morphine, analogous to regimens used clinically for chronic pain management, selectively up-regulates the mu-opioid receptor (MOR) splice variants MOR-1B2 and MOR-1C1 mRNA and functi …
We recently demonstrated in rat spinal cord that a regimen of escalating doses of systemic morphine, analogous to regimens used clinically f …
Emerging role of T3-binding protein mu-crystallin (CRYM) in health and disease.
Aksoy O, Hantusch B, Kenner L. Aksoy O, et al. Trends Endocrinol Metab. 2022 Dec;33(12):804-816. doi: 10.1016/j.tem.2022.09.003. Epub 2022 Nov 5. Trends Endocrinol Metab. 2022. PMID: 36344381 Review.
Triiodothyronine (T3) and thyroxine (T4) are synthesized in the thyroid gland and constitute unique iodine-containing hormones that are constantly regulated by a homeostatic feedback mechanism. ...Modulation of intracellular T3/T4 level contributes to the maintenance of th …
Triiodothyronine (T3) and thyroxine (T4) are synthesized in the thyroid gland and constitute unique iodine-containing hormones that a …
A Narrative Pharmacological Review of Buprenorphine: A Unique Opioid for the Treatment of Chronic Pain.
Gudin J, Fudin J. Gudin J, et al. Pain Ther. 2020 Jun;9(1):41-54. doi: 10.1007/s40122-019-00143-6. Epub 2020 Jan 28. Pain Ther. 2020. PMID: 31994020 Free PMC article. Review.
Buprenorphine is a Schedule III opioid analgesic with unique pharmacodynamic and pharmacokinetic properties that may be preferable to those of Schedule II full mu-opioid receptor agonists. ...Partial agonism at the mu-opioid receptor does not provide partial …
Buprenorphine is a Schedule III opioid analgesic with unique pharmacodynamic and pharmacokinetic properties that may be preferable to …
3,936 results