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1966 1
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1,395 results

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Page 1
Showing results for eric murine
Search for Eric Muringu instead (3 results)
A distinct metabolic and epigenetic state drives trained immunity in HSC-derived macrophages from autoimmune mice.
Mills TS, Kain B, Burchill MA, Danis E, Lucas ED, Culp-Hill R, Cowan CM, Schleicher WE, Patel SB, Tran BT, Cao R, Goodspeed A, Ferrara S, Bevers S, Jirón Tamburini BA, Roede JR, D'Alessandro A, King KY, Pietras EM. Mills TS, et al. Cell Stem Cell. 2024 Nov 7;31(11):1630-1649.e8. doi: 10.1016/j.stem.2024.09.010. Epub 2024 Oct 15. Cell Stem Cell. 2024. PMID: 39413777 Free PMC article.
Using a mouse model of systemic lupus erythematosus (SLE), we show that bone marrow-derived macrophages (BMDMs) from autoimmune mice exhibit hallmark features of TI, including increased Mycobacterium avium killing and inflammatory cytokine production, which are mechanistic …
Using a mouse model of systemic lupus erythematosus (SLE), we show that bone marrow-derived macrophages (BMDMs) from autoimmune mice …
Editorial.
Cox E. Cox E. Vet Microbiol. 2017 Apr;202:1. doi: 10.1016/j.vetmic.2017.05.002. Vet Microbiol. 2017. PMID: 28527490 No abstract available.
A basophil-fibroblast pro-inflammatory axis fuels type 2 skin inflammation.
Imanishi I, Gill R, Wilder A, Restrepo P, Nair A, Cho I, Krueger JG, Guttman-Yassky E, Kim BS, Ji AL. Imanishi I, et al. Cell Rep. 2025 Aug 26;44(8):116114. doi: 10.1016/j.celrep.2025.116114. Epub 2025 Aug 7. Cell Rep. 2025. PMID: 40782349 Free PMC article.
To address this, here, we present a single-cell spatiotemporal atlas of murine type 2 skin inflammation using MERFISH and scRNA-seq. Analyzing 430,000 cells during MC903- and oxazolone-induced dermatitis, we identify 39 cell types, including pro-inflammatory fibroblasts t …
To address this, here, we present a single-cell spatiotemporal atlas of murine type 2 skin inflammation using MERFISH and scRNA-seq. …
Aging disrupts spatiotemporal coordination in the cycling murine ovary.
Lan TCT, Kochersberger A, Raichur R, Szady S, Tran H, Simeonova R, Helmuth A, Minagar A, Orozco Fuentes MJ, Kumar V, Marrero G, Barrera I, Mangiameli S, Shalek AK, Sabeti PC, Chen F, Fischer DS, Garrison JL, Chung H. Lan TCT, et al. Nat Aging. 2026 Jun;6(6):1244-1266. doi: 10.1038/s43587-026-01140-z. Epub 2026 Jun 17. Nat Aging. 2026. PMID: 42310395 Free PMC article.
Dopamine D1-D2 signalling in hippocampus arbitrates approach and avoidance.
Godino A, Salery M, Minier-Toribio AM, Patel V, Fullard JF, Kondev V, Parise EM, Martinez-Rivera FJ, Morel C, Roussos P, Blitzer RD, Nestler EJ. Godino A, et al. Nature. 2025 Jul;643(8071):448-457. doi: 10.1038/s41586-025-08957-5. Epub 2025 May 7. Nature. 2025. PMID: 40335693 Free PMC article.
N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis.
Karmakar M, Minns M, Greenberg EN, Diaz-Aponte J, Pestonjamasp K, Johnson JL, Rathkey JK, Abbott DW, Wang K, Shao F, Catz SD, Dubyak GR, Pearlman E. Karmakar M, et al. Nat Commun. 2020 May 5;11(1):2212. doi: 10.1038/s41467-020-16043-9. Nat Commun. 2020. PMID: 32371889 Free PMC article.
In contrast, we report that although N-GSDMD is required for IL-1beta secretion in NLRP3-activated human and murine neutrophils, N-GSDMD does not localize to the PM or increase PM permeability or pyroptosis. ...
In contrast, we report that although N-GSDMD is required for IL-1beta secretion in NLRP3-activated human and murine neutrophils, N-GS …
Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2.
Peña CJ, Kronman HG, Walker DM, Cates HM, Bagot RC, Purushothaman I, Issler O, Loh YE, Leong T, Kiraly DD, Goodman E, Neve RL, Shen L, Nestler EJ. Peña CJ, et al. Science. 2017 Jun 16;356(6343):1185-1188. doi: 10.1126/science.aan4491. Science. 2017. PMID: 28619944 Free PMC article.
Here we establish a "two-hit" stress model in mice wherein stress at a specific postnatal period increases susceptibility to adult social defeat stress and causes long-lasting transcriptional alterations that prime the ventral tegmental area (VTA)-a brain reward region-to …
Here we establish a "two-hit" stress model in mice wherein stress at a specific postnatal period increases susceptibility to adult so …
Multiscale footprints reveal the organization of cis-regulatory elements.
Hu Y, Horlbeck MA, Zhang R, Ma S, Shrestha R, Kartha VK, Duarte FM, Hock C, Savage RE, Labade A, Kletzien H, Meliki A, Castillo A, Durand NC, Mattei E, Anderson LJ, Tay T, Earl AS, Shoresh N, Epstein CB, Wagers AJ, Buenrostro JD. Hu Y, et al. Nature. 2025 Feb;638(8051):779-786. doi: 10.1038/s41586-024-08443-4. Epub 2025 Jan 22. Nature. 2025. PMID: 39843737 Free PMC article.
We further discover age-associated alterations in the structure of CREs in murine haematopoietic stem cells, including widespread reduction of nucleosome footprints and gain of de novo identified Ets composite motifs. ...
We further discover age-associated alterations in the structure of CREs in murine haematopoietic stem cells, including widespread red …
A mechanistic basis of fast myofiber vulnerability to neuromuscular diseases.
Dos Santos M, Bezprozvannaya S, McAnally JR, Cai C, Liu N, Olson EN. Dos Santos M, et al. Cell Rep. 2025 Jul 22;44(7):115959. doi: 10.1016/j.celrep.2025.115959. Epub 2025 Jul 8. Cell Rep. 2025. PMID: 40632651 Free PMC article.
We found that the fast muscle gene program and the transcription factor Maf were repressed upon denervation. Overexpression of Maf in mice prevented loss of muscle mass caused by denervation by repressing atrophic genes and restoring fast gene expression. Similar repressio …
We found that the fast muscle gene program and the transcription factor Maf were repressed upon denervation. Overexpression of Maf in mic …
1,395 results