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m-Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity.
Rocchi D, González JF, Martín-Cámara O, Perrone MG, Miciaccia M, Scilimati A, Decouty-Pérez C, Parada E, Egea J, Menéndez JC. Rocchi D, et al. Molecules. 2023 Jul 13;28(14):5374. doi: 10.3390/molecules28145374. Molecules. 2023. PMID: 37513247 Free PMC article.
These compounds were synthesized via a three-component reaction of chalcones, beta-ketoesters, and primary amines, followed by hydrolysis/decarboxylation of the ester group. Together with their synthetic intermediates and some urea derivatives, they were studied as inhibit …
These compounds were synthesized via a three-component reaction of chalcones, beta-ketoesters, and primary amines, followed by hydrolysis/de …
From single drug targets to synergistic network pharmacology in ischemic stroke.
Casas AI, Hassan AA, Larsen SJ, Gomez-Rangel V, Elbatreek M, Kleikers PWM, Guney E, Egea J, López MG, Baumbach J, Schmidt HHHW. Casas AI, et al. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7129-7136. doi: 10.1073/pnas.1820799116. Epub 2019 Mar 20. Proc Natl Acad Sci U S A. 2019. PMID: 30894481 Free PMC article.
Bio-nanocomposite edible coatings based on arrowroot starch/cellulose nanocrystals/carnauba wax nanoemulsion containing essential oils to preserve quality and improve shelf life of strawberry.
Oliveira Filho JG, Albiero BR, Calisto ÍH, Bertolo MRV, Oldoni FCA, Egea MB, Bogusz Junior S, de Azeredo HMC, Ferreira MD. Oliveira Filho JG, et al. Int J Biol Macromol. 2022 Oct 31;219:812-823. doi: 10.1016/j.ijbiomac.2022.08.049. Epub 2022 Aug 11. Int J Biol Macromol. 2022. PMID: 35963346
The coatings altered the volatile profile of the fruits during storage, decreasing aldehyde and alcohol concentrations and increasing ester concentrations. Thus, these bio-nanocomposite coatings, especially those containing MEO, can be used as antimicrobial coating materia …
The coatings altered the volatile profile of the fruits during storage, decreasing aldehyde and alcohol concentrations and increasing est …
Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1.
Ries C, Pitsch T, Mentele R, Zahler S, Egea V, Nagase H, Jochum M. Ries C, et al. Biochem J. 2007 Aug 1;405(3):547-58. doi: 10.1042/BJ20070191. Biochem J. 2007. PMID: 17489740 Free PMC article.
The 82 kDa form was not detected in the medium even upon stimulation with a phorbol ester. It is truncated by nine amino acid residues at its N-terminus, lacks O-linked oligosaccharides present in the 94 kDa proMMP-9, but retains N-linked carbohydrates. ...
The 82 kDa form was not detected in the medium even upon stimulation with a phorbol ester. It is truncated by nine amino acid residue …
Involvement of major histocompatibility complex class I antigens in T cell activation.
Dasgupta JD, Egea E, Relias V, Iglesias A, Gladstone P, Yunis EJ. Dasgupta JD, et al. Eur J Immunol. 1990 Jul;20(7):1553-61. doi: 10.1002/eji.1830200722. Eur J Immunol. 1990. PMID: 2143729
On the contrary, these Ab enhance lectin- as well as phorbol ester-induced T cell activation in the absence of M phi. Cross-linking of class I Ag on T cell surface mobilizes cytoplasmic Ca2+, and also enhances the CD3-induced Ca2+ flux inside the cells indicating a functio …
On the contrary, these Ab enhance lectin- as well as phorbol ester-induced T cell activation in the absence of M phi. Cross-linking o …
Ultrastructural changes induced by 12-O-tetradecanoylphorbol 13-acetate in pure cholinergic synaptosomes of Torpedo electric organ.
Egea G, Guitart X, Marsal J. Egea G, et al. J Neurochem. 1991 Nov;57(5):1593-8. doi: 10.1111/j.1471-4159.1991.tb06356.x. J Neurochem. 1991. PMID: 1919576
We have studied the morphological changes induced by the phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment on pure cholinergic synaptosomes from Torpedo electric organ. ...Similar results were found when calcium was not present in the extrasynaptosomal med …
We have studied the morphological changes induced by the phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment on pure c …