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Year Number of Results
1903 1
1905 1
1912 1
1913 1
1914 1
1915 1
1917 1
1918 1
1919 3
1920 1
1922 1
1923 1
1924 5
1925 1
1926 6
1927 5
1928 6
1929 2
1930 8
1931 2
1932 3
1933 4
1934 6
1935 3
1936 5
1937 7
1938 6
1939 11
1940 2
1941 4
1943 3
1944 2
1945 37
1946 54
1947 90
1948 124
1949 72
1950 84
1951 98
1952 119
1953 149
1954 154
1955 162
1956 139
1957 154
1958 193
1959 200
1960 219
1961 217
1962 206
1963 281
1964 299
1965 354
1966 369
1967 402
1968 626
1969 844
1970 820
1971 888
1972 951
1973 876
1974 779
1975 1118
1976 1333
1977 1210
1978 1114
1979 1120
1980 1252
1981 1396
1982 1512
1983 1800
1984 1952
1985 2340
1986 2519
1987 2685
1988 3026
1989 3196
1990 3362
1991 3398
1992 3569
1993 3628
1994 3908
1995 4034
1996 4023
1997 3896
1998 3899
1999 4097
2000 4430
2001 4544
2002 4503
2003 4708
2004 4765
2005 5135
2006 5451
2007 5286
2008 5532
2009 5302
2010 5593
2011 5696
2012 6000
2013 6177
2014 6209
2015 6040
2016 5895
2017 6057
2018 6119
2019 6328
2020 6639
2021 6670
2022 6471
2023 6324
2024 2312

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198,602 results

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The following term was not found in PubMed: 20Marco-Noales
Page 1
Palladium-Catalyzed Tandem Ester Dance/Decarbonylative Coupling Reactions.
Kubo M, Inayama N, Ota E, Yamaguchi J. Kubo M, et al. Org Lett. 2022 Jun 3;24(21):3855-3860. doi: 10.1021/acs.orglett.2c01432. Epub 2022 May 23. Org Lett. 2022. PMID: 35604648
Notably, dance reactions of halides and pseudohalides offer a unique platform for the divergent synthesis of substituted (hetero)aromatic compounds when combined with transition-metal-catalyzed coupling reactions. Herein, we report a tandem reaction of ester dance and deca …
Notably, dance reactions of halides and pseudohalides offer a unique platform for the divergent synthesis of substituted (hetero)aromatic co …
Microbial esterases and ester prodrugs: An unlikely marriage for combating antibiotic resistance.
Larsen EM, Johnson RJ. Larsen EM, et al. Drug Dev Res. 2019 Feb;80(1):33-47. doi: 10.1002/ddr.21468. Epub 2018 Oct 10. Drug Dev Res. 2019. PMID: 30302779 Free PMC article. Review.
Ester prodrugs are normally designed to have simple ester groups, as they are expected to be cleaved and reactivated by a wide spectrum of cellular esterases. ...In this review, we highlight the important pathogenic and xenobiotic functions of microbial esterases an …
Ester prodrugs are normally designed to have simple ester groups, as they are expected to be cleaved and reactivated by a wide …
Catalytic antibodies.
Tramontano A, Janda KD, Lerner RA. Tramontano A, et al. Science. 1986 Dec 19;234(4783):1566-70. doi: 10.1126/science.3787261. Science. 1986. PMID: 3787261
Monoclonal antibodies elicited to haptens that are analogs of the transition state for hydrolysis of carboxylic esters behaved as enzymic catalysts with the appropriate substrates. ...Mechanisms are proposed to account for the different chemical behavior of these antibodie …
Monoclonal antibodies elicited to haptens that are analogs of the transition state for hydrolysis of carboxylic esters behaved as enz …
Lactose esters: synthesis and biotechnological applications.
Staroń J, Dąbrowski JM, Cichoń E, Guzik M. Staroń J, et al. Crit Rev Biotechnol. 2018 Mar;38(2):245-258. doi: 10.1080/07388551.2017.1332571. Epub 2017 Jun 6. Crit Rev Biotechnol. 2018. PMID: 28585445 Review.
Biodegradable nonionic sugar esters-based surfactants have been gaining more and more attention in recent years due to their chemical plasticity that enables the various applications of these molecules. In this review, various synthesis methods and biotechnological implica …
Biodegradable nonionic sugar esters-based surfactants have been gaining more and more attention in recent years due to their chemical …
[Evaluation of the Oral Absorption of Ester-type Prodrugs].
Ohura K. Ohura K. Yakugaku Zasshi. 2020;140(3):369-376. doi: 10.1248/yakushi.19-00225. Yakugaku Zasshi. 2020. PMID: 32115554 Free article. Review. Japanese.
The first-pass hydrolysis of oral ester-type prodrugs in the liver and intestine is mediated mainly by hCE1 and hCE2 of the respective predominant carboxylesterase (CES) isozymes. In order to provide high blood concentrations of the parent drugs, it is preferable that prod …
The first-pass hydrolysis of oral ester-type prodrugs in the liver and intestine is mediated mainly by hCE1 and hCE2 of the respectiv …
Phthalate esters: occurrence, toxicity, bioremediation, and advanced oxidation processes.
Kumari M, Pulimi M. Kumari M, et al. Water Sci Technol. 2023 May;87(9):2090-2115. doi: 10.2166/wst.2023.119. Water Sci Technol. 2023. PMID: 37186617 Review.
Phthalic acid esters are emerging pollutants, commonly used as plasticizers that are categorized as hazardous endocrine-disrupting chemicals (EDCs). ...This paper gives an overview of the research related to phthalate ester contamination and degradation methods by c …
Phthalic acid esters are emerging pollutants, commonly used as plasticizers that are categorized as hazardous endocrine-disrupting ch …
Microbial production of short and medium chain esters: Enzymes, pathways, and applications.
Kruis AJ, Bohnenkamp AC, Patinios C, van Nuland YM, Levisson M, Mars AE, van den Berg C, Kengen SWM, Weusthuis RA. Kruis AJ, et al. Biotechnol Adv. 2019 Nov 15;37(7):107407. doi: 10.1016/j.biotechadv.2019.06.006. Epub 2019 Jun 11. Biotechnol Adv. 2019. PMID: 31195083 Review.
Microbial conversion of biomass-derived sugars into esters may provide a sustainable alternative. This review provides a broad overview of natural ester production by microorganisms. ...This large and versatile group of enzymes condense an alcohol and an acyl-CoA to …
Microbial conversion of biomass-derived sugars into esters may provide a sustainable alternative. This review provides a broad overvi …
Fast-Acting Antibacterial, Self-Deactivating Polyionene Esters.
Krumm C, Trump S, Benski L, Wilken J, Oberhaus F, Köller M, Tiller JC. Krumm C, et al. ACS Appl Mater Interfaces. 2020 May 13;12(19):21201-21209. doi: 10.1021/acsami.9b19313. Epub 2020 Jan 9. ACS Appl Mater Interfaces. 2020. PMID: 31916737
Because of hydrolysis of the ester groups, the PBI esters are degraded and deactivated in aqueous media. ...While the more hydrophilic polymers require hydrolyses of only 19 to 30% of the ester groups to become practically inactive, the more hydrophobic PBI …
Because of hydrolysis of the ester groups, the PBI esters are degraded and deactivated in aqueous media. ...While the more hyd …
alpha-Imino Esters in Organic Synthesis: Recent Advances.
Eftekhari-Sis B, Zirak M. Eftekhari-Sis B, et al. Chem Rev. 2017 Jun 28;117(12):8326-8419. doi: 10.1021/acs.chemrev.7b00064. Epub 2017 Jun 12. Chem Rev. 2017. PMID: 28603976 Review.
alpha-Imino esters are useful precursors for the synthesis of a variety of types of natural and unnatural alpha-amino acid derivatives, with a wide range of biological activities. Due to the adjacent ester group, alpha-imino esters are more reactive relative …
alpha-Imino esters are useful precursors for the synthesis of a variety of types of natural and unnatural alpha-amino acid derivative …
Autohydrolysis of Diglycine-Activated Succinic Esters Boosts Cellular Uptake.
Guo J, Tan W, He H, Xu B. Guo J, et al. Angew Chem Int Ed Engl. 2023 Sep 4;62(36):e202308022. doi: 10.1002/anie.202308022. Epub 2023 Jul 31. Angew Chem Int Ed Engl. 2023. PMID: 37468437
Rapid cellular uptake of synthetic molecules remains a challenge, and the motif frequently employed to generate prodrugs, succinic ester, unfortunately lowers the efficacy of the desired drugs due to their slow ester hydrolysis and low cell entry. ...Specifically, a …
Rapid cellular uptake of synthetic molecules remains a challenge, and the motif frequently employed to generate prodrugs, succinic ester …
198,602 results
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