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First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus: Latin American Group for the Study of Lupus (GLADEL, Grupo Latino Americano de Estudio del Lupus)-Pan-American League of Associations of Rheumatology (PANLAR).
Pons-Estel BA, Bonfa E, Soriano ER, Cardiel MH, Izcovich A, Popoff F, Criniti JM, Vásquez G, Massardo L, Duarte M, Barile-Fabris LA, García MA, Amigo MC, Espada G, Catoggio LJ, Sato EI, Levy RA, Acevedo Vásquez EM, Chacón-Díaz R, Galarza-Maldonado CM, Iglesias Gamarra AJ, Molina JF, Neira O, Silva CA, Vargas Peña A, Gómez-Puerta JA, Scolnik M, Pons-Estel GJ, Ugolini-Lopes MR, Savio V, Drenkard C, Alvarellos AJ, Ugarte-Gil MF, Babini A, Cavalcanti A, Cardoso Linhares FA, Haye Salinas MJ, Fuentes-Silva YJ, Montandon de Oliveira E Silva AC, Eraso Garnica RM, Herrera Uribe S, Gómez-Martín D, Robaina Sevrini R, Quintana RM, Gordon S, Fragoso-Loyo H, Rosario V, Saurit V, Appenzeller S, Dos Reis Neto ET, Cieza J, González Naranjo LA, González Bello YC, Collado MV, Sarano J, Retamozo S, Sattler ME, Gamboa-Cárdenas RV, Cairoli E, Conti SM, Amezcua-Guerra LM, Silveira LH, Borba EF, Pera MA, Alba Moreyra PB, Arturi V, Berbotto GA, Gerling C, Gobbi CA, Gervasoni VL, Scherbarth HR, Brenol JCT, Cavalcanti F, Costallat LTL, Da Silva NA, Monticielo OA, Seguro LPC, Xavier RM, Llanos C, Montúfar Guardado RA, Garcia de la Torre I, Pineda C, Portela Hernández M, Danza A, Guibert-Toledano M, Reyes GL,… See abstract for full author list ➔ Pons-Estel BA, et al. Ann Rheum Dis. 2018 Nov;77(11):1549-1557. doi: 10.1136/annrheumdis-2018-213512. Epub 2018 Jul 25. Ann Rheum Dis. 2018. PMID: 30045853 Free PMC article.
Time to diagnosis in systemic lupus erythematosus: Associated factors and its impact on damage accrual and mortality. Data from a multi-ethnic, multinational Latin American lupus cohort.
Nieto R, Quintana R, Zavala-Flores E, Serrano R, Roberts K, Catoggio LJ, García MA, Berbotto GA, Saurit V, Bonfa E, Borba EF, Lavras Costallat LT, Da Silva NA, Sato EI, Tavares Brenol JC, Massardo L, Neira OJ, Vázquez G, Guibert Toledano M, Pascual-Ramos V, Sauza Del Pozo MJ, Barile-Fabris LA, Amigo MC, García De La Torre I, Acevedo-Vásquez EM, Segami MI, Chacón-Díaz R, Esteva-Spinetti MH, Alarcón GS, Pons-Estel BA, Pons-Estel GJ. Nieto R, et al. Lupus. 2024 Apr;33(4):340-346. doi: 10.1177/09612033241232821. Epub 2024 Feb 9. Lupus. 2024. PMID: 38334100
Socio-demographic, clinical/laboratory, disease activity, damage, and mortality between those with a longer and a shorter time to diagnosis were compared using descriptive statistical tests. ...
Socio-demographic, clinical/laboratory, disease activity, damage, and mortality between those with a longer and a shorter time to dia …
Transancestral mapping and genetic load in systemic lupus erythematosus.
Langefeld CD, Ainsworth HC, Cunninghame Graham DS, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Almlöf JC, Acevedo-Vásquez EM, Alarcón GS, Babini AM, Baca V, Bengtsson AA, Berbotto GA, Bijl M, Brown EE, Brunner HI, Cardiel MH, Catoggio L, Cervera R, Cucho-Venegas JM, Dahlqvist SR, D'Alfonso S, Da Silva BM, de la Rúa Figueroa I, Doria A, Edberg JC, Endreffy E, Esquivel-Valerio JA, Fortin PR, Freedman BI, Frostegård J, García MA, de la Torre IG, Gilkeson GS, Gladman DD, Gunnarsson I, Guthridge JM, Huggins JL, James JA, Kallenberg CGM, Kamen DL, Karp DR, Kaufman KM, Kottyan LC, Kovács L, Laustrup H, Lauwerys BR, Li QZ, Maradiaga-Ceceña MA, Martín J, McCune JM, McWilliams DR, Merrill JT, Miranda P, Moctezuma JF, Nath SK, Niewold TB, Orozco L, Ortego-Centeno N, Petri M, Pineau CA, Pons-Estel BA, Pope J, Raj P, Ramsey-Goldman R, Reveille JD, Russell LP, Sabio JM, Aguilar-Salinas CA, Scherbarth HR, Scorza R, Seldin MF, Sjöwall C, Svenungsson E, Thompson SD, Toloza SMA, Truedsson L, Tusié-Luna T, Vasconcelos C, Vilá LM, Wallace DJ, Weisman MH, Wither JE, Bhangale T, Oksenberg JR, Rioux JD, Gregersen PK, Syvänen AC, Rönnblom L, Criswell LA, Jacob … See abstract for full author list ➔ Langefeld CD, et al. Nat Commun. 2017 Jul 17;8:16021. doi: 10.1038/ncomms16021. Nat Commun. 2017. PMID: 28714469 Free PMC article.
A longitudinal multiethnic study of biomarkers in systemic lupus erythematosus: Launching the GLADEL 2.0 Study Group.
Gómez-Puerta JA, Pons-Estel GJ, Quintana R, Nieto R, Serrano Morales RM, Harvey GB, Wojdyla D, Scolnik M, Funes Soaje C, Alba Moreyra P, Novatti E, Arizpe F, Berbotto GA, González Lucero L, Porta S, Pérez N, Rodriguez AM, Appenzeller S, de Oliveira E Silva Montadon AC, Monticielo OA, Cavalcanti FS, Machado Ribeiro F, Borba EF, Torres Dos Reis-Neto E, Neira O, Chahuán JM, Mimica M, Aroca Martínez G, Tobón GJ, Vásquez G, Quintana-Lopez G, Moreno Alvarez MJ, Saavedra MÁ, Cristobal MP, Fragoso-Loyo H, Amezcua-Guerra LM, González-Bello YC, Abud-Mendoza C, Esquivel-Valerio JA, Duarte M, Acosta Colman I, Mora-Trujillo C, Reátegui-Sokolova C, Calvo Quiroz AA, Muñoz-Louis R, Cairoli E, Rosas I, Rebella M, Cardiel MH, García de la Torre I, Catoggio LJ, Alarcón GS, Pons-Estel BA. Gómez-Puerta JA, et al. Lupus. 2021 Jan 28:961203320988586. doi: 10.1177/0961203320988586. Online ahead of print. Lupus. 2021. PMID: 33509067
Effects of Amerindian Genetic Ancestry on Clinical Variables and Therapy in Patients with Rheumatoid Arthritis.
Sánchez E, García de la Torre I, Sacnún M, Goñi M, Berbotto G, Paira S, Musuruana JL, Graf C, Alvarellos A, Messina OD, Babini A, Strusberg I, Marcos JC, Scherbarth H, Spindler A, Quinteros A, Toloza S, Moreno JLC, Catoggio LJ, Tate G, Eimon A, Citera G, Pellet AC, Nasswetter G, Cardiel MH, Miranda P, Ballesteros F, Esquivel-Valerio JA, Maradiaga-Ceceña MA, Acevedo-Vásquez EM, García CG, Tusié-Luna T, Pons-Estel BA, Alarcón-Riquelme ME; GENAR Study. Sánchez E, et al. J Rheumatol. 2017 Dec;44(12):1804-1812. doi: 10.3899/jrheum.160485. Epub 2017 Nov 1. J Rheumatol. 2017. PMID: 29093158 Free article.
Predictors of renal damage in systemic lupus erythematous patients: data from a multiethnic, multinational Latin American lupus cohort (GLADEL).
Reátegui-Sokolova C, Ugarte-Gil MF, Harvey GB, Wojdyla D, Pons-Estel GJ, Quintana R, Serrano-Morales RM, Sacnun MP, Catoggio LJ, Soriano ER, García MA, Saurit V, Alvarellos A, Caeiro F, Berbotto GA, Sato EI, Borba Neto EF, Bonfa E, de Oliveira E Silva Montandon AC, Da Silva NA, Cavalcanti F, Vásquez G, Guibert-Toledano M, Reyes-Llerena GA, Massardo L, Neira OJ, Cardiel MH, Barile-Fabris LA, Amigo MC, Silveira LH, Portela-Hernández M, Garcia de la Torre I, Segami MI, Chacón-Diaz R, Esteva-Spinetti MH, Alarcón GS, Pons-Estel BA; GLADEL. Reátegui-Sokolova C, et al. RMD Open. 2020 Dec;6(3):e001299. doi: 10.1136/rmdopen-2020-001299. RMD Open. 2020. PMID: 33310863 Free PMC article.
Possible predictors of renal damage at the time of LN diagnosis were examined: proteinuria, low complement, anti-double-stranded DNA antibodies, red cell casts, creatinine level, hypertension, renal activity (assessed by the Systemic Lupus Erythematosus Disease Activity …
Possible predictors of renal damage at the time of LN diagnosis were examined: proteinuria, low complement, anti-double-stranded DNA antibod …
Clinical features, damage accrual, and survival in patients with familial systemic lupus erythematosus: data from a multi-ethnic, multinational Latin American lupus cohort.
Quintana R, Pons-Estel GJ, Roberts K, Sacnún M, Serrano R, Nieto R, Conti S, Gervasoni V, Catoggio LJ, Soriano ER, Scolnik M, García MA, Alvarellos A, Saurit V, Berbotto GA, Sato EI, Costallat LTL, Neto EFB, Bonfa E, Xavier RM, de Oliveira E Silva Montandon AC, Molina-Restrepo JF, Iglesias-Gamarra A, Guibert-Toledano M, Reyes-Llerena GA, Massardo L, Neira OJ, Cardiel MH, Barile-Fabris LA, Amigo MC, Silveira LH, Torre IG, Acevedo-Vásquez EM, Ugarte-Gil MF, Alfaro-Lozano JL, Segami MI, Chacón-Díaz R, Esteva-Spinetti MH, Gomez-Puerta JA, Alarcón GS, Pons-Estel BA. Quintana R, et al. Lupus. 2020 Aug;29(9):1140-1145. doi: 10.1177/0961203320935184. Epub 2020 Jun 30. Lupus. 2020. PMID: 32605527
Familial lupus was defined as patients with a first-degree SLE relative; these relatives were interviewed in person or by telephone. Clinical variables, disease activity, damage, and mortality were compared. Odds ratios (OR) and 95% confidence intervals (CI) were estimated …
Familial lupus was defined as patients with a first-degree SLE relative; these relatives were interviewed in person or by telephone. Clinica …
Remission and Low Disease Activity Status (LDAS) protect lupus patients from damage occurrence: data from a multiethnic, multinational Latin American Lupus Cohort (GLADEL).
Ugarte-Gil MF, Wojdyla D, Pons-Estel GJ, Catoggio LJ, Drenkard C, Sarano J, Berbotto GA, Borba EF, Sato EI, Tavares Brenol JC, Uribe O, Ramirez Gómez LA, Guibert-Toledano M, Massardo L, Cardiel MH, Silveira LH, Chacón-Diaz R, Alarcón GS, Pons-Estel BA; GLADEL. Ugarte-Gil MF, et al. Ann Rheum Dis. 2017 Dec;76(12):2071-2074. doi: 10.1136/annrheumdis-2017-211814. Epub 2017 Sep 22. Ann Rheum Dis. 2017. PMID: 28939626
OBJECTIVE: To evaluate disease activity statuses' (DAS') impact on systemic lupus erythematosus (SLE) outcomes. MATERIALS AND METHODS: Four DAS were defined: remission off-therapy: SLE Disease Activity Index (SLEDAI)=0, no prednisone or immunosuppressive drugs (IS); …
OBJECTIVE: To evaluate disease activity statuses' (DAS') impact on systemic lupus erythematosus (SLE) outcomes. MATERIALS AND METHODS …
The GLADEL multinational Latin American prospective inception cohort of 1,214 patients with systemic lupus erythematosus: ethnic and disease heterogeneity among "Hispanics".
Pons-Estel BA, Catoggio LJ, Cardiel MH, Soriano ER, Gentiletti S, Villa AR, Abadi I, Caeiro F, Alvarellos A, Alarcón-Segovia D; Grupo Latinoamericano de Estudio del Lupus (GLADEL). Pons-Estel BA, et al. Medicine (Baltimore). 2004 Jan;83(1):1-17. doi: 10.1097/01.md.0000104742.42401.e2. Medicine (Baltimore). 2004. PMID: 14747764 Free article.
We were then able to evaluate prospectively socioeconomic variables, ethnicity, type of medical care, clinical and laboratory features, disease activity, damage, and mortality at each site. A coordinating center controlled the quality of the information submitted. ...
We were then able to evaluate prospectively socioeconomic variables, ethnicity, type of medical care, clinical and laboratory features, dise …
Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
Alarcón-Riquelme ME, Ziegler JT, Molineros J, Howard TD, Moreno-Estrada A, Sánchez-Rodríguez E, Ainsworth HC, Ortiz-Tello P, Comeau ME, Rasmussen A, Kelly JA, Adler A, Acevedo-Vázquez EM, Cucho-Venegas JM, García-De la Torre I, Cardiel MH, Miranda P, Catoggio LJ, Maradiaga-Ceceña M, Gaffney PM, Vyse TJ, Criswell LA, Tsao BP, Sivils KL, Bae SC, James JA, Kimberly RP, Kaufman KM, Harley JB, Esquivel-Valerio JA, Moctezuma JF, García MA, Berbotto GA, Babini AM, Scherbarth H, Toloza S, Baca V, Nath SK, Aguilar Salinas C, Orozco L, Tusié-Luna T, Zidovetzki R, Pons-Estel BA, Langefeld CD, Jacob CO. Alarcón-Riquelme ME, et al. Arthritis Rheumatol. 2016 Apr;68(4):932-43. doi: 10.1002/art.39504. Arthritis Rheumatol. 2016. PMID: 26606652 Free PMC article.