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Design and synthesis of phosphonoacetic acid (PPA) ester and amide bioisosters of ribofuranosylnucleoside diphosphates as potential ribonucleotide reductase inhibitors and evaluation of their enzyme inhibitory, cytostatic and antiviral activity.
Manfredini S, Solaroli N, Angusti A, Nalin F, Durini E, Vertuani S, Pricl S, Ferrone M, Spadari S, Focher F, Verri A, De Clercq E, Balzarini J. Manfredini S, et al. Among authors: nalin f. Antivir Chem Chemother. 2003 Jul;14(4):183-94. doi: 10.1177/095632020301400403. Antivir Chem Chemother. 2003. PMID: 14582847 Free article.