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Page 1
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7.
Gütschow M, Eynde JJV, Jampilek J, Kang C, Mangoni AA, Fossa P, Karaman R, Trabocchi A, Scott PJH, Reynisson J, Rapposelli S, Galdiero S, Winum JY, Brullo C, Prokai-Tatrai K, Sharma AK, Schapira M, Azuma YT, Cerchia L, Spetea M, Torri G, Collina S, Geronikaki A, García-Sosa AT, Vasconcelos MH, Sousa ME, Kosalec I, Tuccinardi T, Duarte IF, Salvador JAR, Bertinaria M, Pellecchia M, Amato J, Rastelli G, Gomes PAC, Guedes RC, Sabatier JM, Estévez-Braun A, Pagano B, Mangani S, Ragno R, Kokotos G, Brindisi M, González FV, Borges F, Miloso M, Rautio J, Muñoz-Torrero D. Gütschow M, et al. Among authors: gonzalez fv. Molecules. 2020 Jun 28;25(13):2968. doi: 10.3390/molecules25132968. Molecules. 2020. PMID: 32605268 Free PMC article.
Advances in the Development of SARS-CoV-2 Mpro Inhibitors.
Agost-Beltrán L, de la Hoz-Rodríguez S, Bou-Iserte L, Rodríguez S, Fernández-de-la-Pradilla A, González FV. Agost-Beltrán L, et al. Among authors: gonzalez fv. Molecules. 2022 Apr 14;27(8):2523. doi: 10.3390/molecules27082523. Molecules. 2022. PMID: 35458721 Free PMC article. Review.
Rhodesain inhibitors on the edge of reversibility-irreversibility.
Agost-Beltrán L, Zimmer C, Räder HJ, Kersten C, Schirmeister T, Rodríguez S, González FV. Agost-Beltrán L, et al. Among authors: gonzalez fv. Bioorg Chem. 2024 Dec;153:107830. doi: 10.1016/j.bioorg.2024.107830. Epub 2024 Sep 19. Bioorg Chem. 2024. PMID: 39306902 Free article.
Profiling Cysteine Proteases Activities in Neuroinflammatory Cells.
Agost-Beltrán L, Canseco-Rodríguez A, Schirmeister T, Rodríguez S, Sánchez-Pérez AM, González FV. Agost-Beltrán L, et al. Among authors: gonzalez fv. ChemMedChem. 2025 Feb 1;20(3):e202400520. doi: 10.1002/cmdc.202400520. Epub 2024 Nov 20. ChemMedChem. 2025. PMID: 39475209 Free PMC article.
Investigation of the Compatibility between Warheads and Peptidomimetic Sequences of Protease Inhibitors-A Comprehensive Reactivity and Selectivity Study.
Müller P, Meta M, Meidner JL, Schwickert M, Meyr J, Schwickert K, Kersten C, Zimmer C, Hammerschmidt SJ, Frey A, Lahu A, de la Hoz-Rodríguez S, Agost-Beltrán L, Rodríguez S, Diemer K, Neumann W, Gonzàlez FV, Engels B, Schirmeister T. Müller P, et al. Among authors: gonzalez fv. Int J Mol Sci. 2023 Apr 13;24(8):7226. doi: 10.3390/ijms24087226. Int J Mol Sci. 2023. PMID: 37108388 Free PMC article.
Peptidyl nitroalkene inhibitors of main protease rationalized by computational and crystallographic investigations as antivirals against SARS-CoV-2.
Medrano FJ, de la Hoz-Rodríguez S, Martí S, Arafet K, Schirmeister T, Hammerschmidt SJ, Müller C, González-Martínez Á, Santillana E, Ziebuhr J, Romero A, Zimmer C, Weldert A, Zimmermann R, Lodola A, Świderek K, Moliner V, González FV. Medrano FJ, et al. Among authors: gonzalez fv. Commun Chem. 2024 Jan 18;7(1):15. doi: 10.1038/s42004-024-01104-7. Commun Chem. 2024. PMID: 38238420 Free PMC article.
Dipeptidyl Nitroalkenes as Potent Reversible Inhibitors of Cysteine Proteases Rhodesain and Cruzain.
Latorre A, Schirmeister T, Kesselring J, Jung S, Johé P, Hellmich UA, Heilos A, Engels B, Krauth-Siegel RL, Dirdjaja N, Bou-Iserte L, Rodríguez S, González FV. Latorre A, et al. Among authors: gonzalez fv. ACS Med Chem Lett. 2016 Sep 21;7(12):1073-1076. doi: 10.1021/acsmedchemlett.6b00276. eCollection 2016 Dec 8. ACS Med Chem Lett. 2016. PMID: 27994740 Free PMC article.
30 results