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2002 1
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2009 7
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Page 1
Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.
Altincekic N, Jores N, Löhr F, Richter C, Ehrhardt C, Blommers MJJ, Berg H, Öztürk S, Gande SL, Linhard V, Orts J, Abi Saad MJ, Bütikofer M, Kaderli J, Karlsson BG, Brath U, Hedenström M, Gröbner G, Sauer UH, Perrakis A, Langer J, Banci L, Cantini F, Fragai M, Grifagni D, Barthel T, Wollenhaupt J, Weiss MS, Robertson A, Bax A, Sreeramulu S, Schwalbe H. Altincekic N, et al. Among authors: cantini f. ACS Chem Biol. 2024 Feb 16;19(2):563-574. doi: 10.1021/acschembio.3c00720. Epub 2024 Jan 17. ACS Chem Biol. 2024. PMID: 38232960 Free PMC article.
Development of a GC-376 Based Peptidomimetic PROTAC as a Degrader of 3-Chymotrypsin-like Protease of SARS-CoV-2.
Grifagni D, Lenci E, De Santis A, Orsetti A, Barracchia CG, Tedesco F, Bellini Puglielli R, Lucarelli F, Lauriola A, Assfalg M, Cantini F, Calderone V, Guardavaccaro D, Trabocchi A, D'Onofrio M, Ciofi-Baffoni S. Grifagni D, et al. Among authors: cantini f. ACS Med Chem Lett. 2024 Jan 10;15(2):250-257. doi: 10.1021/acsmedchemlett.3c00498. eCollection 2024 Feb 8. ACS Med Chem Lett. 2024. PMID: 38352832 Free PMC article.
Fragment-based approach to identify IDO1 inhibitor building blocks.
Coletti A, Camponeschi F, Albini E, Greco FA, Maione V, Custodi C, Ianni F, Grohmann U, Orabona C, Cantini F, Macchiarulo A. Coletti A, et al. Among authors: cantini f. Eur J Med Chem. 2017 Dec 1;141:169-177. doi: 10.1016/j.ejmech.2017.09.044. Epub 2017 Oct 3. Eur J Med Chem. 2017. PMID: 29031064 Free article.
75 results