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3'-UTR SNP rs2229611 in G6PC1 affects mRNA stability, expression and Glycogen Storage Disease type-Ia risk.
Karthi S, Rajeshwari M, Francis A, Saravanan M, Varalakshmi P, Houlden H, Thangaraj K, Ashokkumar B. Karthi S, et al. Clin Chim Acta. 2017 Aug;471:46-54. doi: 10.1016/j.cca.2017.05.016. Epub 2017 May 11. Clin Chim Acta. 2017. PMID: 28502559
Functional validation performed in HepG2 cells using luciferase constructs showed significant (P<0.05) decrease in expression than wild-type 3'-UTR due to curtailed mRNA stability. Furthermore, AU-rich elements (AREs) mediated regulation of G6PC1 expression characterize …
Functional validation performed in HepG2 cells using luciferase constructs showed significant (P<0.05) decrease in expression than wild-t …
International experience of mechanical thrombectomy during the COVID-19 pandemic: insights from STAR and ENRG.
Al Kasab S, Almallouhi E, Alawieh A, Levitt MR, Jabbour P, Sweid A, Starke RM, Saini V, Wolfe SQ, Fargen KM, Arthur AS, Goyal N, Pandhi A, Fragata I, Maier I, Matouk C, Grossberg JA, Howard BM, Kan P, Hafeez M, Schirmer CM, Crowley RW, Joshi KC, Tjoumakaris SI, Chowdry S, Ares W, Ogilvy C, Gomez-Paz S, Rai AT, Mokin M, Guerrero W, Park MS, Mascitelli JR, Yoo A, Williamson R, Grande AW, Crosa RJ, Webb S, Psychogios MN, Ducruet AF, Holmstedt CA, Ringer AJ, Spiotta AM; STAR collaborators. Al Kasab S, et al. J Neurointerv Surg. 2020 Nov;12(11):1039-1044. doi: 10.1136/neurintsurg-2020-016671. Epub 2020 Aug 25. J Neurointerv Surg. 2020. PMID: 32843359 Free PMC article.