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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 2
1954 1
1963 5
1964 4
1965 2
1966 2
1967 2
1968 2
1969 1
1971 1
1972 1
1973 4
1974 1
1975 5
1976 9
1977 4
1978 7
1979 2
1980 8
1981 11
1982 4
1983 2
1984 12
1985 5
1986 10
1987 16
1988 9
1989 14
1990 13
1991 22
1992 13
1993 23
1994 15
1995 14
1996 18
1997 37
1998 30
1999 34
2000 52
2001 63
2002 75
2003 83
2004 99
2005 94
2006 136
2007 127
2008 167
2009 162
2010 208
2011 237
2012 228
2013 305
2014 406
2015 385
2016 449
2017 416
2018 446
2019 495
2020 568
2021 607
2022 544
2023 256

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6,182 results

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Page 1
Critical Roles of the Circadian Transcription Factor BMAL1 in Reproductive Endocrinology and Fertility.
Jiang Y, Li S, Xu W, Ying J, Qu Y, Jiang X, Zhang A, Yue Y, Zhou R, Ruan T, Li J, Mu D. Jiang Y, et al. Front Endocrinol (Lausanne). 2022 Mar 2;13:818272. doi: 10.3389/fendo.2022.818272. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35311235 Free PMC article. Review.
Increasing evidence has demonstrated the essential role of BMAL1 in reproductive physiology. For instance, BMAL1-knockout (KO) mice were infertile, with impaired reproductive organs and gametes. Additionally, in BMAL1-KO mice, hormone secretion and signaling of hypo …
Increasing evidence has demonstrated the essential role of BMAL1 in reproductive physiology. For instance, BMAL1-knockout (KO) mice w …
Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression.
Manta CP, Leibing T, Friedrich M, Nolte H, Adrian M, Schledzewski K, Krzistetzko J, Kirkamm C, David Schmid C, Xi Y, Stojanovic A, Tonack S, de la Torre C, Hammad S, Offermanns S, Krüger M, Cerwenka A, Platten M, Goerdt S, Géraud C. Manta CP, et al. Circulation. 2022 Dec 6;146(23):1783-1799. doi: 10.1161/CIRCULATIONAHA.121.058615. Epub 2022 Nov 3. Circulation. 2022. PMID: 36325910 Free article.
Here, we comprehensively studied how targeting Stab1 and Stab2 affects atherosclerosis. METHODS: ApoE-KO mice were interbred with Stab1-KO and Stab2-KO mice and fed a Western diet. ...RESULTS: Spontaneous and Western diet-associated atherogenesis was signific …
Here, we comprehensively studied how targeting Stab1 and Stab2 affects atherosclerosis. METHODS: ApoE-KO mice were interbred with Sta …
Homer1 promotes dendritic spine growth through ankyrin-G and its loss reshapes the synaptic proteome.
Yoon S, Piguel NH, Khalatyan N, Dionisio LE, Savas JN, Penzes P. Yoon S, et al. Mol Psychiatry. 2021 Jun;26(6):1775-1789. doi: 10.1038/s41380-020-00991-1. Epub 2021 Jan 4. Mol Psychiatry. 2021. PMID: 33398084 Free PMC article.
Here, we used computational approaches to identify global functions for proteins containing the Homer1-interacting PPXXF motif within the postsynaptic compartment. Ankyrin-G was one of the most topologically important nodes in the postsynaptic peripheral membrane subnetwor …
Here, we used computational approaches to identify global functions for proteins containing the Homer1-interacting PPXXF motif within the po …
Gq-Mediated Arrhythmogenic Signaling Promotes Atrial Fibrillation.
Hohendanner F, Prabhu A, Wilck N, Stangl V, Pieske B, Stangl K, Althoff TF. Hohendanner F, et al. Biomedicines. 2023 Feb 11;11(2):526. doi: 10.3390/biomedicines11020526. Biomedicines. 2023. PMID: 36831062 Free PMC article.
Baseline electrophysiological properties, including heart rate, sinus node recovery time, and atrial as well as AV nodal effective refractory periods, were comparable in G(q)-KO and control mice. However, inducibility and mean duration of AF episodes were significan …
Baseline electrophysiological properties, including heart rate, sinus node recovery time, and atrial as well as AV nodal effective refractor …
Retinal Dopamine D2 Receptors Participate in the Development of Myopia in Mice.
Huang F, Shu Z, Huang Q, Chen K, Yan W, Wu W, Yang J, Wang Q, Wang F, Zhang C, Qu J, Zhou X. Huang F, et al. Invest Ophthalmol Vis Sci. 2022 Jan 3;63(1):24. doi: 10.1167/iovs.63.1.24. Invest Ophthalmol Vis Sci. 2022. PMID: 35050306 Free PMC article.
Mice in both groups received daily intraperitoneal injections of either the D2R antagonist sulpiride (8 g/g) or vehicle alone. FDM was also induced in retina- (Six3creD2Rfl/fl) or fibroblast-specific (S100a4creD2Rfl/fl) D2R-KO mice. A subset of retina-specifi …
Mice in both groups received daily intraperitoneal injections of either the D2R antagonist sulpiride (8 g/g) or vehicle alone. …
Understanding cadherin EGF LAG seven-pass G-type receptors.
Wang XJ, Zhang DL, Xu ZG, Ma ML, Wang WB, Li LL, Han XL, Huo Y, Yu X, Sun JP. Wang XJ, et al. J Neurochem. 2014 Dec;131(6):699-711. doi: 10.1111/jnc.12955. Epub 2014 Oct 26. J Neurochem. 2014. PMID: 25280249 Free PMC article. Review.
The cadherin epidermal growth factor (EGF) laminin G (LAG) seven-pass G-type receptors (CELSRs) are a special subgroup of adhesion G protein-coupled receptors, which are pivotal regulators of many biologic processes such as neuronal/endocrine cell differentia …
The cadherin epidermal growth factor (EGF) laminin G (LAG) seven-pass G-type receptors (CELSRs) are a special subgroup of adhe …
Evidence that the granulocyte colony-stimulating factor (G-CSF) receptor plays a role in the pharmacokinetics of G-CSF and PegG-CSF using a G-CSF-R KO model.
Kotto-Kome AC, Fox SE, Lu W, Yang BB, Christensen RD, Calhoun DA. Kotto-Kome AC, et al. Pharmacol Res. 2004 Jul;50(1):55-8. doi: 10.1016/j.phrs.2003.12.011. Pharmacol Res. 2004. PMID: 15082029
We sought to clarify the role of receptor-mediated clearance of filgrastim and pegfilgrastim using wild-type (WT) mice or mice with a non-functional G-CSF-R (knockout, KO). We administered single doses of filgrastim or pegfilgrastim (10 or 100 microg kg(-1)) intrave …
We sought to clarify the role of receptor-mediated clearance of filgrastim and pegfilgrastim using wild-type (WT) mice or mice with a non-fu …
Knockout of γ-Adducin Promotes NG-Nitro-L-Arginine-Methyl-Ester-Induced Hypertensive Renal Injury.
Fan L, Gao W, Liu Y, Jefferson JR, Fan F, Roman RJ. Fan L, et al. J Pharmacol Exp Ther. 2021 Apr;377(1):189-198. doi: 10.1124/jpet.120.000408. Epub 2021 Jan 7. J Pharmacol Exp Ther. 2021. PMID: 33414130 Free PMC article.
The acute hemodynamic effect of L-NAME and its chronic effects on hypertension and renal injury were compared in FHH 1(Brown Norway) (FHH 1(BN)) congenic rats (WT) expressing wild-type Add3 gene versus FHH 1(BN) Add3 KO rats. RBF was well autoregulated in WT rats but impai …
The acute hemodynamic effect of L-NAME and its chronic effects on hypertension and renal injury were compared in FHH 1(Brown Norway) (FHH 1( …
G protein subunit β1 is an important mediator of the late stage of endochondral ossification.
Ruengsinpinya L, Murakami T, Nakamura E, Takahata Y, Hata K, Nakaminami Y, Okae H, Nishimura R. Ruengsinpinya L, et al. Biochem Biophys Res Commun. 2020 Nov 26;533(1):90-96. doi: 10.1016/j.bbrc.2020.08.119. Epub 2020 Sep 11. Biochem Biophys Res Commun. 2020. PMID: 32928505
G protein signaling plays important roles in skeletal development. G protein subunit beta1 (GNB1) is a component of the G protein complex and is associated with G protein signaling. ...
G protein signaling plays important roles in skeletal development. G protein subunit beta1 (GNB1) is a component of the G
Gpr137b is an orphan G-protein-coupled receptor associated with M2 macrophage polarization.
Islam Z, Inui T, Ishibashi O. Islam Z, et al. Biochem Biophys Res Commun. 2019 Feb 12;509(3):657-663. doi: 10.1016/j.bbrc.2018.12.140. Epub 2018 Dec 27. Biochem Biophys Res Commun. 2019. PMID: 30595385
Two independent Gpr137b-KO clones were isolated, which were demonstrated to have frameshifting 188-nucleotide deletions at a region containing the ATG start codon of Gpr137b. ...Microarray analysis revealed that the IL-4-induced gene expression of representative M2 macroph …
Two independent Gpr137b-KO clones were isolated, which were demonstrated to have frameshifting 188-nucleotide deletions at a region c …
6,182 results