Therapeutic Exploitation of GPR18: Beyond the Cannabinoids?
Morales P, Lago-Fernandez A, Hurst DP, Sotudeh N, Brailoiu E, Reggio PH, Abood ME, Jagerovic N.
Morales P, et al.
J Med Chem. 2020 Dec 10;63(23):14216-14227. doi: 10.1021/acs.jmedchem.0c00926. Epub 2020 Sep 23.
J Med Chem. 2020.
PMID: 32914978
Free PMC article.
Review.
GPR18 is a G-protein-coupled receptor that belongs to the orphan class A family. Even though it shares low sequence homology with the cannabinoid receptors CB(1)R and CB(2)R, a growing body of research suggests its relationship with the endocannabinoid system, not only bec …
GPR18 is a G-protein-coupled receptor that belongs to the orphan class A family. Even though it shares low sequence homology with the …