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2019 9
2020 5
2021 4
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Geoffrey Burnstock, our friend and magister: the diadenosine polyphosphate connection.
Miras-Portugal MT, Gualix J. Miras-Portugal MT, et al. Purinergic Signal. 2021 Mar;17(1):79-84. doi: 10.1007/s11302-020-09736-9. Epub 2020 Oct 6. Purinergic Signal. 2021. PMID: 33025428 Free PMC article. Review.
Sometimes, ideas on a specific area get suddenly exhausted and then it is the time for a privileged mind to think in a different way and reach the turning point to introduce a new paradigm. This happened to Geoffrey Burnstock, a heterodox thinker and nonconformist s …
Sometimes, ideas on a specific area get suddenly exhausted and then it is the time for a privileged mind to think in a different way
Effect of Surface Treatment and Cement on Fracture Load of Traditional Zirconia (3Y), Translucent Zirconia (5Y), and Lithium Disilicate Crowns.
Lawson NC, Jurado CA, Huang CT, Morris GP, Burgess JO, Liu PR, Kinderknecht KE, Lin CP, Givan DA. Lawson NC, et al. J Prosthodont. 2019 Jul;28(6):659-665. doi: 10.1111/jopr.13088. Epub 2019 Jun 11. J Prosthodont. 2019. PMID: 31145492 Free PMC article.
Crowns were load cycled (100,000 cycles, 100 N force, 24C water) and then loaded with a steel indenter until failure. A three-way ANOVA examined the effects of material, cement, and surface treatment on fracture load. ...
Crowns were load cycled (100,000 cycles, 100 N force, 24C water) and then loaded with a steel indenter until failure. A three-way ANO …
Synthetic metabolons for metabolic engineering.
Singleton C, Howard TP, Smirnoff N. Singleton C, et al. J Exp Bot. 2014 May;65(8):1947-54. doi: 10.1093/jxb/eru050. Epub 2014 Mar 3. J Exp Bot. 2014. PMID: 24591054 Review.
This provides experimental evidence that metabolons may have a general advantage and opens the way to improving the outcome of metabolic engineering in plants by including synthetic metabolons in the toolbox....
This provides experimental evidence that metabolons may have a general advantage and opens the way to improving the outcome of metabo …
Back to basics: Making predictions in the orbitofrontal-amygdala circuit.
Sharpe MJ, Schoenbaum G. Sharpe MJ, et al. Neurobiol Learn Mem. 2016 May;131:201-6. doi: 10.1016/j.nlm.2016.04.009. Epub 2016 Apr 23. Neurobiol Learn Mem. 2016. PMID: 27112314 Free PMC article. Review.
However, electrophysiological data demonstrates critical differences in the way neurons in these regions respond to predictive cues, revealing a difference in their functional role. ...
However, electrophysiological data demonstrates critical differences in the way neurons in these regions respond to predictive cues, …
Purinergic signalling in the kidney - A beginning with Geoffrey Burnstock.
Unwin RJ. Unwin RJ. Auton Neurosci. 2021 Sep;234:102833. doi: 10.1016/j.autneu.2021.102833. Epub 2021 Jun 5. Auton Neurosci. 2021. PMID: 34118763
This not an original publication or a current and up-to-date review of purinergic signalling and kidney function, but rather a tribute to Professor Geoffrey Burnstock, written as a short and personal memoir of our early collaborative work together on this topic: our beginn …
This not an original publication or a current and up-to-date review of purinergic signalling and kidney function, but rather a tribute to Pr …
Fluorescent protein-based technologies: shedding new light on the plant endomembrane system.
Sparkes I, Brandizzi F. Sparkes I, et al. Plant J. 2012 Apr;70(1):96-107. doi: 10.1111/j.1365-313X.2011.04884.x. Plant J. 2012. PMID: 22449045 Free article. Review.
Without doubt, GFP and spectral derivatives have revolutionized the way biologists approach their journey toward the discovery of how plant cells function. It is fascinating that in its early days GFP was used merely for localization studies, but as time progressed researc …
Without doubt, GFP and spectral derivatives have revolutionized the way biologists approach their journey toward the discovery of how …
Investigating ROS, RNS, and H2S-Sensitive Signaling Proteins.
Williams E, Whiteman M, Wood ME, Wilson ID, Ladomery MR, Allainguillaume J, Teklic T, Lisjak M, Hancock JT. Williams E, et al. Methods Mol Biol. 2019;1990:27-42. doi: 10.1007/978-1-4939-9463-2_3. Methods Mol Biol. 2019. PMID: 31148060
The modification of proteins is a key way to alter their activity and function. Often thiols, cysteine residues, on proteins are attractive targets for such modification. ...There are a variety of techniques to find proteins which may be altered in this way but here …
The modification of proteins is a key way to alter their activity and function. Often thiols, cysteine residues, on proteins are attr …
60 YEARS OF NEUROENDOCRINOLOGY: MEMOIR: Harris' neuroendocrine revolution: of portal vessels and self-priming.
Fink G. Fink G. J Endocrinol. 2015 Aug;226(2):T13-24. doi: 10.1530/JOE-15-0130. Epub 2015 May 12. J Endocrinol. 2015. PMID: 25967698 Review.
Geoffrey Harris, while still a medical student at Cambridge, was the first researcher (1937) to provide experimental proof for the then tentative view that the anterior pituitary gland was controlled by the CNS. ...Neuroendocrine principles are illustrated in this Thematic
Geoffrey Harris, while still a medical student at Cambridge, was the first researcher (1937) to provide experimental proof for the th
Genomic and personalized medicine: foundations and applications.
Ginsburg GS, Willard HF. Ginsburg GS, et al. Transl Res. 2009 Dec;154(6):277-87. doi: 10.1016/j.trsl.2009.09.005. Epub 2009 Oct 1. Transl Res. 2009. PMID: 19931193 Review.
Although these and other scientific findings are making their way from the genome to the clinic, the full application of genomic and personalized medicine in health care will require dramatic changes in regulatory and reimbursement policies as well as legislative protectio …
Although these and other scientific findings are making their way from the genome to the clinic, the full application of genomic and …
Prior Cocaine Use Alters the Normal Evolution of Information Coding in Striatal Ensembles during Value-Guided Decision-Making.
Mueller LE, Sharpe MJ, Stalnaker TA, Wikenheiser AM, Schoenbaum G. Mueller LE, et al. J Neurosci. 2021 Jan 13;41(2):342-353. doi: 10.1523/JNEUROSCI.1755-20.2020. Epub 2020 Nov 20. J Neurosci. 2021. PMID: 33219006 Free PMC article.
This can be achieved by assigning learning in different contexts to compartmentalized "states." Though not often framed this way, the maladaptive behavior observed in individuals with SUDs may result from a failure to properly encode states because of drug-induced neural a …
This can be achieved by assigning learning in different contexts to compartmentalized "states." Though not often framed this way, the …
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