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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 2
1980 8
1981 2
1982 5
1983 3
1984 4
1985 4
1986 5
1987 4
1988 7
1989 4
1990 2
1991 5
1992 4
1993 5
1994 7
1995 3
1996 5
1997 12
1998 5
1999 6
2000 4
2001 6
2002 4
2003 11
2004 3
2005 8
2006 12
2007 8
2008 15
2009 15
2010 19
2011 14
2012 13
2013 16
2014 7
2015 9
2016 17
2017 14
2018 13
2019 11
2020 16
2021 12
2022 8
2023 14
2024 18
2025 0

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354 results

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Page 1
SLC transporters as therapeutic targets: emerging opportunities.
Lin L, Yee SW, Kim RB, Giacomini KM. Lin L, et al. Among authors: giacomini km. Nat Rev Drug Discov. 2015 Aug;14(8):543-60. doi: 10.1038/nrd4626. Epub 2015 Jun 26. Nat Rev Drug Discov. 2015. PMID: 26111766 Free PMC article. Review.
Membrane transporters in drug development.
International Transporter Consortium; Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, Lee CA, Niemi M, Polli JW, Sugiyama Y, Swaan PW, Ware JA, Wright SH, Yee SW, Zamek-Gliszczynski MJ, Zhang L. International Transporter Consortium, et al. Among authors: giacomini km. Nat Rev Drug Discov. 2010 Mar;9(3):215-36. doi: 10.1038/nrd3028. Nat Rev Drug Discov. 2010. PMID: 20190787 Free PMC article. Review.
The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin-Associated Musculoskeletal Symptoms.
Cooper-DeHoff RM, Niemi M, Ramsey LB, Luzum JA, Tarkiainen EK, Straka RJ, Gong L, Tuteja S, Wilke RA, Wadelius M, Larson EA, Roden DM, Klein TE, Yee SW, Krauss RM, Turner RM, Palaniappan L, Gaedigk A, Giacomini KM, Caudle KE, Voora D. Cooper-DeHoff RM, et al. Among authors: giacomini km. Clin Pharmacol Ther. 2022 May;111(5):1007-1021. doi: 10.1002/cpt.2557. Epub 2022 Mar 11. Clin Pharmacol Ther. 2022. PMID: 35152405 Free PMC article.
Membrane transporters in drug development and as determinants of precision medicine.
Galetin A, Brouwer KLR, Tweedie D, Yoshida K, Sjöstedt N, Aleksunes L, Chu X, Evers R, Hafey MJ, Lai Y, Matsson P, Riselli A, Shen H, Sparreboom A, Varma MVS, Yang J, Yang X, Yee SW, Zamek-Gliszczynski MJ, Zhang L, Giacomini KM. Galetin A, et al. Among authors: giacomini km. Nat Rev Drug Discov. 2024 Apr;23(4):255-280. doi: 10.1038/s41573-023-00877-1. Epub 2024 Jan 24. Nat Rev Drug Discov. 2024. PMID: 38267543 Free PMC article. Review.
A genome-wide association analysis reveals new pathogenic pathways in gout.
Major TJ, Takei R, Matsuo H, Leask MP, Sumpter NA, Topless RK, Shirai Y, Wang W, Cadzow MJ, Phipps-Green AJ, Li Z, Ji A, Merriman ME, Morice E, Kelley EE, Wei WH, McCormick SPA, Bixley MJ, Reynolds RJ, Saag KG, Fadason T, Golovina E, O'Sullivan JM, Stamp LK, Dalbeth N, Abhishek A, Doherty M, Roddy E, Jacobsson LTH, Kapetanovic MC, Melander O, Andrés M, Pérez-Ruiz F, Torres RJ, Radstake T, Jansen TL, Janssen M, Joosten LAB, Liu R, Gaal OI, Crişan TO, Rednic S, Kurreeman F, Huizinga TWJ, Toes R, Lioté F, Richette P, Bardin T, Ea HK, Pascart T, McCarthy GM, Helbert L, Stibůrková B, Tausche AK, Uhlig T, Vitart V, Boutin TS, Hayward C, Riches PL, Ralston SH, Campbell A, MacDonald TM; FAST Study Group; Nakayama A, Takada T, Nakatochi M, Shimizu S, Kawamura Y, Toyoda Y, Nakaoka H, Yamamoto K, Matsuo K, Shinomiya N, Ichida K; Japan Gout Genomics Consortium; Lee C; Asia Pacific Gout Consortium; Bradbury LA, Brown MA, Robinson PC, Buchanan RRC, Hill CL, Lester S, Smith MD, Rischmueller M, Choi HK, Stahl EA, Miner JN, Solomon DH, Cui J, Giacomini KM, Brackman DJ, Jorgenson EM; GlobalGout Genetics Consortium; Liu H, Susztak K; 23andMe Research Team; Shringarpure S, So A, Okada Y, Li C,… See abstract for full author list ➔ Major TJ, et al. Among authors: giacomini km. Nat Genet. 2024 Nov;56(11):2392-2406. doi: 10.1038/s41588-024-01921-5. Epub 2024 Oct 15. Nat Genet. 2024. PMID: 39406924
Functional genomics of OCTN2 variants informs protein-specific variant effect predictor for Carnitine Transporter Deficiency.
Koleske ML, McInnes G, Brown JEH, Thomas N, Hutchinson K, Chin MY, Koehl A, Arkin MR, Schlessinger A, Gallagher RC, Song YS, Altman RB, Giacomini KM. Koleske ML, et al. Among authors: giacomini km. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2210247119. doi: 10.1073/pnas.2210247119. Epub 2022 Nov 7. Proc Natl Acad Sci U S A. 2022. PMID: 36343260 Free PMC article.
Structural and molecular basis of choline uptake into the brain by FLVCR2.
Cater RJ, Mukherjee D, Gil-Iturbe E, Erramilli SK, Chen T, Koo K, Santander N, Reckers A, Kloss B, Gawda T, Choy BC, Zhang Z, Katewa A, Larpthaveesarp A, Huang EJ, Mooney SWJ, Clarke OB, Yee SW, Giacomini KM, Kossiakoff AA, Quick M, Arnold T, Mancia F. Cater RJ, et al. Among authors: giacomini km. Nature. 2024 May;629(8012):704-709. doi: 10.1038/s41586-024-07326-y. Epub 2024 May 1. Nature. 2024. PMID: 38693257
Trends in Clinical Pharmacology and Therapeutics.
Minichmayr IK, Smith DM, Giacomini KM, van der Graaf PH. Minichmayr IK, et al. Among authors: giacomini km. Clin Pharmacol Ther. 2023 Jul;114(1):11-14. doi: 10.1002/cpt.2931. Clin Pharmacol Ther. 2023. PMID: 37335056 No abstract available.
Clinical Pharmacology & Therapeutics 2030.
van der Graaf PH, Giacomini KM. van der Graaf PH, et al. Among authors: giacomini km. Clin Pharmacol Ther. 2020 Jan;107(1):13-16. doi: 10.1002/cpt.1705. Clin Pharmacol Ther. 2020. PMID: 31863685 No abstract available.
354 results