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2016 1
2017 2
2019 3
2020 1
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Page 1
The Role of PALB2 in the DNA Damage Response and Cancer Predisposition.
Nepomuceno TC, De Gregoriis G, de Oliveira FMB, Suarez-Kurtz G, Monteiro AN, Carvalho MA. Nepomuceno TC, et al. Among authors: de gregoriis g. Int J Mol Sci. 2017 Aug 31;18(9):1886. doi: 10.3390/ijms18091886. Int J Mol Sci. 2017. PMID: 28858227 Free PMC article. Review.
A global functional analysis of missense mutations reveals two major hotspots in the PALB2 tumor suppressor.
Rodrigue A, Margaillan G, Torres Gomes T, Coulombe Y, Montalban G, da Costa E Silva Carvalho S, Milano L, Ducy M, De-Gregoriis G, Dellaire G, Araújo da Silva W Jr, Monteiro AN, Carvalho MA, Simard J, Masson JY. Rodrigue A, et al. Among authors: de gregoriis g. Nucleic Acids Res. 2019 Nov 18;47(20):10662-10677. doi: 10.1093/nar/gkz780. Nucleic Acids Res. 2019. PMID: 31586400 Free PMC article.
Impact of amino acid substitutions at secondary structures in the BRCT domains of the tumor suppressor BRCA1: Implications for clinical annotation.
Fernandes VC, Golubeva VA, Di Pietro G, Shields C, Amankwah K, Nepomuceno TC, de Gregoriis G, Abreu RBV, Harro C, Gomes TT, Silva RF, Suarez-Kurtz G, Couch FJ, Iversen ES, Monteiro ANA, Carvalho MA. Fernandes VC, et al. Among authors: de gregoriis g. J Biol Chem. 2019 Apr 12;294(15):5980-5992. doi: 10.1074/jbc.RA118.005274. Epub 2019 Feb 14. J Biol Chem. 2019. PMID: 30765603 Free PMC article.
Functional assays provide a robust tool for the clinical annotation of genetic variants of uncertain significance.
Woods NT, Baskin R, Golubeva V, Jhuraney A, De-Gregoriis G, Vaclova T, Goldgar DE, Couch FJ, Carvalho MA, Iversen ES, Monteiro AN. Woods NT, et al. Among authors: de gregoriis g. NPJ Genom Med. 2016;1:16001-. doi: 10.1038/npjgenmed.2016.1. Epub 2016 Mar 2. NPJ Genom Med. 2016. PMID: 28781887 Free PMC article.
Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance.
Tacconi EM, Badie S, De Gregoriis G, Reisländer T, Lai X, Porru M, Folio C, Moore J, Kopp A, Baguña Torres J, Sneddon D, Green M, Dedic S, Lee JW, Batra AS, Rueda OM, Bruna A, Leonetti C, Caldas C, Cornelissen B, Brino L, Ryan A, Biroccio A, Tarsounas M. Tacconi EM, et al. Among authors: de gregoriis g. EMBO Mol Med. 2019 Jul;11(7):e9982. doi: 10.15252/emmm.201809982. Epub 2019 May 24. EMBO Mol Med. 2019. PMID: 31273933 Free PMC article.
Network of Interactions between ZIKA Virus Non-Structural Proteins and Human Host Proteins.
Golubeva VA, Nepomuceno TC, Gregoriis G, Mesquita RD, Li X, Dash S, Garcez PP, Suarez-Kurtz G, Izumi V, Koomen J, Carvalho MA, Monteiro ANA. Golubeva VA, et al. Among authors: gregoriis g. Cells. 2020 Jan 8;9(1):153. doi: 10.3390/cells9010153. Cells. 2020. PMID: 31936331 Free PMC article.
DNA repair genes PAXIP1 and TP53BP1 expression is associated with breast cancer prognosis.
De Gregoriis G, Ramos JA, Fernandes PV, Vignal GM, Brianese RC, Carraro DM, Monteiro AN, Struchiner CJ, Suarez-Kurtz G, Vianna-Jorge R, de Carvalho MA. De Gregoriis G, et al. Cancer Biol Ther. 2017 Jun 3;18(6):439-449. doi: 10.1080/15384047.2017.1323590. Epub 2017 May 5. Cancer Biol Ther. 2017. PMID: 28475402 Free PMC article.
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