Multicenter international cohort study of haploinsufficiency of A20 reveals novel genetic architecture and phenotypic evolution.
He T, Wang J, Carpio Tumba M, Wang S, Luo Y, Chen J, Li G, Shu Z, Zhang S, Stone DL, Huang Y, Lv Q, Xiong W, Wang J, Yu Z, Cuff CV, Kairis E, Kethri A, Towheed A, Goyette K, Karri U, Wang J, Liu C, Romeo T, Alsina L, Rosenberg DL, Clemente D, López-Robledillo JC, Rong Z, Zhao X, Jiang L, Aldave-Becerra JC, Muñoz-Urribarri AB, Oommen PT, Campbell-Stokes P, Zhu M, Liu P, Guo L, Xu Y, Yu Z, Tong H, Qiu X, Zhang Y, Chen H, Zhang C, Ou J, Liu C, Liu J, Shen Y, Cao J, Zhang X, Yang K, Bao Y, Li Z, Cao J, Duan Y, Liu F, Shi B, Sun M, Ma L, Chen Y, Yang W, Han X, Ma S, Luo J, Gu W, Yu G, Shi W, Zhao R, Sun L, Li W, An Y, Tang X, Zhao X, Han T, Ma J, Li Y, Piao Y, Sun F, Zhang D, Yin M, Zheng S, Li T, Niu H, Lin L, Mei S, Zhou F, Yang S, Li D, Yan M, Zeng H, Zeng P, Zheng W, Li X, Li X, Liu Y, Huang L, Yu H, Fan Z, Shen M, Lu M, Fang Z, Rimland CA, Song H, Peterson LW, Yousuf Al-Nesf MA, Aqel S, Mudawi DS, Raje N, Slowik V, Harris JG, Snyder B, Scheffler-Mendoza S, Yamazaki-Nakashimada MA, Cooper MA, Lau YL, Cetin Gedik K, Wang W, Ying W, Hou J, Zhou Q, Sun B, Sun J, Wang X, Ombrello AK, Huang Y, Wu HL, Sun L, Mao H, Yu X, Liu Z, Aksentijevich I, Kastner DL, Schwartz DM, Yang J, Zhou Q.
He T, et al.
J Allergy Clin Immunol. 2026 Jun;157(6):1395-1410. doi: 10.1016/j.jaci.2026.02.002. Epub 2026 Feb 13.
J Allergy Clin Immunol. 2026.
PMID: 41692116
