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PMID: 34949836
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Class B G protein-coupled receptors (GPCRs) are notoriously difficult to target by small molecules because their large orthosteric peptide-binding pocket embedded deep within the transmembrane domain limits the identification and development of nonpeptide small molecule li …
Class B G protein-coupled receptors (GPCRs) are notoriously difficult to target by small molecules because their large orthosteric pe …