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Page 1
Did you mean H. juppner (211 results)?
Natural products in drug discovery: advances and opportunities.
Atanasov AG, Zotchev SB, Dirsch VM; International Natural Product Sciences Taskforce; Supuran CT. Atanasov AG, et al. Nat Rev Drug Discov. 2021 Mar;20(3):200-216. doi: 10.1038/s41573-020-00114-z. Epub 2021 Jan 28. Nat Rev Drug Discov. 2021. PMID: 33510482 Free PMC article. Review.
The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.
McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF. McAlpine JB, et al. Nat Prod Rep. 2019 Jan 1;36(1):35-107. doi: 10.1039/c7np00064b. Epub 2018 Jul 13. Nat Prod Rep. 2019. PMID: 30003207 Free PMC article. Review.
Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase.
Pein H, Ville A, Pace S, Temml V, Garscha U, Raasch M, Alsabil K, Viault G, Dinh CP, Guilet D, Troisi F, Neukirch K, König S, Bilancia R, Waltenberger B, Stuppner H, Wallert M, Lorkowski S, Weinigel C, Rummler S, Birringer M, Roviezzo F, Sautebin L, Helesbeux JJ, Séraphin D, Mosig AS, Schuster D, Rossi A, Richomme P, Werz O, Koeberle A. Pein H, et al. Nat Commun. 2018 Sep 20;9(1):3834. doi: 10.1038/s41467-018-06158-5. Nat Commun. 2018. PMID: 30237488 Free PMC article.
New taxonomically significant sesquiterpenoids from Leontodon autumnalis.
Zidorn C, Ellmerer-Müller EP, Ongania KH, Sturm S, Stuppner H. Zidorn C, et al. J Nat Prod. 2000 Jun;63(6):812-6. doi: 10.1021/np990554j. J Nat Prod. 2000. PMID: 10869207
The known compounds were identified by means of (1)H and (13)C NMR spectroscopy as crepidiaside A (1) and B (2). The structures of the new compounds were determined by extensive 1D and 2D NMR experiments as 15-glucopyranosyloxy-2-oxo-guaia-3,11(13)-dien-1alp ha,5alpha, 6be …
The known compounds were identified by means of (1)H and (13)C NMR spectroscopy as crepidiaside A (1) and B (2). The structures of th …
Dammarane-type triterpenoid saponins from Salvia russellii Benth.
Hafez Ghoran S, Firuzi O, Asadollahi M, Stuppner H, Alilou M, Jassbi AR. Hafez Ghoran S, et al. Phytochemistry. 2021 Apr;184:112653. doi: 10.1016/j.phytochem.2020.112653. Epub 2021 Jan 29. Phytochemistry. 2021. PMID: 33524860
The chemical structures of the aforementioned compounds were characterized, using detailed spectroscopic analyses, including high-resolution mass spectrometry and 1D and 2D NMR ((1)H-(1)H COSY, TOCSY, HSQC, HMBC and NOESY) spectroscopy as well as physicochemical pro …
The chemical structures of the aforementioned compounds were characterized, using detailed spectroscopic analyses, including high-resolution …
Eudesmane derivatives from Hieracium intybaceum.
Grass S, Zidorn C, Ellmerer EP, Stuppner H. Grass S, et al. Chem Biodivers. 2004 Feb;1(2):353-60. doi: 10.1002/cbdv.200490031. Chem Biodivers. 2004. PMID: 17191853
Two new eudesmanolides, 4beta-H,3beta-(beta-D-glucopyranosyloxy)eudesma-1,11(13)-dien-12,6-olide (5a) and 3beta-D-glucopyranosyloxyeudesma-1,4(15),11(13)-trien-12,6-olide (5b), as well as two related, known compounds, tuberiferin (7a) and dehydrobrachylaenolide (7b), were …
Two new eudesmanolides, 4beta-H,3beta-(beta-D-glucopyranosyloxy)eudesma-1,11(13)-dien-12,6-olide (5a) and 3beta-D-glucopyranosyloxyeu …
Microtubule inhibition as a proposed mechanism for the anthelmintic effect of phytochemicals isolated from Cicerbita alpina.
Horgan MJ, Sigg I, Poulopoulou I, Rodriguez-Mejias FJ, Albertini E, Fusani P, Fischer F, Martinidou E, Schuster D, Martens S, Dürr PJ, Gauly M, Stuppner H, Weiss A, Temml V, Siewert B. Horgan MJ, et al. Sci Rep. 2025 Feb 3;15(1):4108. doi: 10.1038/s41598-024-73958-9. Sci Rep. 2025. PMID: 39900941 Free PMC article.
Furthermore, luteolin was found to inhibit C. elegans egg hatching (luteolin | 65% EH | c = 10 M | t = 10 h) within the range of the control albendazole. Both identified anthelmintic phytochemicals were found to affect tubulin polymerisation at a concentration of c = 50 …
Furthermore, luteolin was found to inhibit C. elegans egg hatching (luteolin | 65% EH | c = 10 M | t = 10 h) within the range of the …
Leoligin, the Major Lignan from Edelweiss (Leontopodium nivale subsp. alpinum), Promotes Cholesterol Efflux from THP-1 Macrophages.
Wang L, Ladurner A, Latkolik S, Schwaiger S, Linder T, Hošek J, Palme V, Schilcher N, Polanský O, Heiss EH, Stangl H, Mihovilovic MD, Stuppner H, Dirsch VM, Atanasov AG. Wang L, et al. J Nat Prod. 2016 Jun 24;79(6):1651-7. doi: 10.1021/acs.jnatprod.6b00227. Epub 2016 May 24. J Nat Prod. 2016. PMID: 27220065 Free PMC article.
Western blot analysis revealed that the protein levels of the cholesterol efflux transporters ABCA1 and ABCG1 were upregulated, whereas the SR-B1 protein level remained unchanged upon treatment with leoligin (10 muM, 24 h). Quantitative reverse transcription PCR further un …
Western blot analysis revealed that the protein levels of the cholesterol efflux transporters ABCA1 and ABCG1 were upregulated, whereas the …
33 results