Novel Insights Into the Sulfated Glucuronic Acid-Based Anti-SARS-CoV-2 Mechanism of Exopolysaccharides From Halophilic Archaeon Haloarcula hispanica.
Xu Y, Li Y, You X, Pei C, Wang Z, Jiao S, Zhao X, Lin X, Lü Y, Jin C, Gao GF, Li J, Wang Q, Du Y.
Xu Y, et al.
Front Chem. 2022 Apr 27;10:871509. doi: 10.3389/fchem.2022.871509. eCollection 2022.
Front Chem. 2022.
PMID: 35572116
Free PMC article.
In this study, it was found exopolysaccharides (EPSs) from halophilic archaeon Haloarcula hispanica ATCC33960 can bind to the spike protein of SARS-CoV-2 with the binding constant K(D) of 2.23 nM, block the binding of spike protein to Vero E6 and bronchial epithelia …
In this study, it was found exopolysaccharides (EPSs) from halophilic archaeon Haloarcula hispanica ATCC33960 can bind to the …