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1956 1
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1997 3
1999 2
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2001 1
2002 2
2003 2
2004 1
2005 3
2006 3
2007 5
2008 5
2009 7
2010 7
2011 8
2012 10
2013 21
2014 12
2015 17
2016 13
2017 31
2018 22
2019 27
2020 35
2021 29
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243 results
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Showing results for halting liu
Search for Haoting Liu instead (1 results)
TGF-β suppresses type 2 immunity to cancer.
Liu M, Kuo F, Capistrano KJ, Kang D, Nixon BG, Shi W, Chou C, Do MH, Stamatiades EG, Gao S, Li S, Chen Y, Hsieh JJ, Hakimi AA, Taniuchi I, Chan TA, Li MO. Liu M, et al. Nature. 2020 Nov;587(7832):115-120. doi: 10.1038/s41586-020-2836-1. Epub 2020 Oct 21. Nature. 2020. PMID: 33087928 Free PMC article.
Here we show that depletion of transforming growth factor-beta receptor 2 (TGFBR2) in CD4(+) T cells, but not CD8(+) T cells, halts cancer progression as a result of tissue healing and remodelling of the blood vasculature, causing cancer cell hypoxia and death in distant a …
Here we show that depletion of transforming growth factor-beta receptor 2 (TGFBR2) in CD4(+) T cells, but not CD8(+) T cells, halts c …
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
Johnston SC, Easton JD, Farrant M, Barsan W, Conwit RA, Elm JJ, Kim AS, Lindblad AS, Palesch YY; Clinical Research Collaboration, Neurological Emergencies Treatment Trials Network, and the POINT Investigators. Johnston SC, et al. N Engl J Med. 2018 Jul 19;379(3):215-225. doi: 10.1056/NEJMoa1800410. Epub 2018 May 16. N Engl J Med. 2018. PMID: 29766750 Free PMC article. Clinical Trial.
RESULTS: A total of 4881 patients were enrolled at 269 international sites. The trial was halted after 84% of the anticipated number of patients had been enrolled because the data and safety monitoring board had determined that the combination of clopidogrel and aspirin wa …
RESULTS: A total of 4881 patients were enrolled at 269 international sites. The trial was halted after 84% of the anticipated number …
T-cell immunity of SARS-CoV: Implications for vaccine development against MERS-CoV.
Liu WJ, Zhao M, Liu K, Xu K, Wong G, Tan W, Gao GF. Liu WJ, et al. Antiviral Res. 2017 Jan;137:82-92. doi: 10.1016/j.antiviral.2016.11.006. Epub 2016 Nov 11. Antiviral Res. 2017. PMID: 27840203 Free PMC article. Review.
Over 12 years have elapsed since severe acute respiratory syndrome (SARS) triggered the first global alert for coronavirus infections. Virus transmission in humans was quickly halted by public health measures and human infections of SARS coronavirus (SARS-CoV) have not bee …
Over 12 years have elapsed since severe acute respiratory syndrome (SARS) triggered the first global alert for coronavirus infections. Virus …
Renal protective effects of empagliflozin via inhibition of EMT and aberrant glycolysis in proximal tubules.
Li J, Liu H, Takagi S, Nitta K, Kitada M, Srivastava SP, Takagaki Y, Kanasaki K, Koya D. Li J, et al. JCI Insight. 2020 Mar 26;5(6):e129034. doi: 10.1172/jci.insight.129034. JCI Insight. 2020. PMID: 32134397 Free PMC article.
Sodium glucose cotransporter 2 (SGLT2) inhibitors are beneficial in halting diabetic kidney disease; however, the complete mechanisms have not yet been elucidated. ...
Sodium glucose cotransporter 2 (SGLT2) inhibitors are beneficial in halting diabetic kidney disease; however, the complete mechanisms …
Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer.
Tchou J, Zhao Y, Levine BL, Zhang PJ, Davis MM, Melenhorst JJ, Kulikovskaya I, Brennan AL, Liu X, Lacey SF, Posey AD Jr, Williams AD, So A, Conejo-Garcia JR, Plesa G, Young RM, McGettigan S, Campbell J, Pierce RH, Matro JM, DeMichele AM, Clark AS, Cooper LJ, Schuchter LM, Vonderheide RH, June CH. Tchou J, et al. Cancer Immunol Res. 2017 Dec;5(12):1152-1161. doi: 10.1158/2326-6066.CIR-17-0189. Epub 2017 Nov 6. Cancer Immunol Res. 2017. PMID: 29109077 Free PMC article. Clinical Trial.
We found that the cell-surface molecule c-Met was expressed in 50% of breast tumors, prompting the construction of a CAR T cell specific for c-Met, which halted tumor growth in immune-incompetent mice with tumor xenografts. ...
We found that the cell-surface molecule c-Met was expressed in 50% of breast tumors, prompting the construction of a CAR T cell specific for …
TFEB is a master regulator of tumor-associated macrophages in breast cancer.
Li Y, Hodge J, Liu Q, Wang J, Wang Y, Evans TD, Altomare D, Yao Y, Murphy EA, Razani B, Fan D. Li Y, et al. J Immunother Cancer. 2020 Jun;8(1):e000543. doi: 10.1136/jitc-2020-000543. J Immunother Cancer. 2020. PMID: 32487570 Free PMC article.
Mphi-specific TFEB deficiency promotes, while activation of TFEB using the natural disaccharide trehalose halts, breast tumor development by modulating TAMs. Analysis of human patient genome database reveals that expression levels of TFEB, SOCS3 and PPARgamma are positive …
Mphi-specific TFEB deficiency promotes, while activation of TFEB using the natural disaccharide trehalose halts, breast tumor develop …
Danazol Treatment for Telomere Diseases.
Townsley DM, Dumitriu B, Liu D, Biancotto A, Weinstein B, Chen C, Hardy N, Mihalek AD, Lingala S, Kim YJ, Yao J, Jones E, Gochuico BR, Heller T, Wu CO, Calado RT, Scheinberg P, Young NS. Townsley DM, et al. N Engl J Med. 2016 May 19;374(20):1922-31. doi: 10.1056/NEJMoa1515319. N Engl J Med. 2016. PMID: 27192671 Free PMC article. Clinical Trial.
Hematologic response to treatment at various time points was the secondary efficacy end point. RESULTS: After 27 patients were enrolled, the study was halted early, because telomere attrition was reduced in all 12 patients who could be evaluated for the primary end point; …
Hematologic response to treatment at various time points was the secondary efficacy end point. RESULTS: After 27 patients were enrolled, the …
Deoxycholic acid modulates the progression of gallbladder cancer through N6-methyladenosine-dependent microRNA maturation.
Lin R, Zhan M, Yang L, Wang H, Shen H, Huang S, Huang X, Xu S, Zhang Z, Li W, Liu Q, Shi Y, Chen W, Yu J, Wang J. Lin R, et al. Oncogene. 2020 Jun;39(26):4983-5000. doi: 10.1038/s41388-020-1349-6. Epub 2020 Jun 8. Oncogene. 2020. PMID: 32514152 Free PMC article.
Here, we analyzed human GBC samples and found that DCA was significantly downregulated in GBC, and reduced levels of DCA was associated with poor clinical outcome in patients with GBC. DCA treatment impeded tumor progression by halting cell proliferation. DCA decreased miR …
Here, we analyzed human GBC samples and found that DCA was significantly downregulated in GBC, and reduced levels of DCA was associated with …
Malaria Elimination and Eradication.
Shretta R, Liu J, Cotter C, Cohen J, Dolenz C, Makomva K, Newby G, Ménard D, Phillips A, Tatarsky A, Gosling R, Feachem R. Shretta R, et al. In: Holmes KK, Bertozzi S, Bloom BR, Jha P, editors. Major Infectious Diseases. 3rd edition. Washington (DC): The International Bank for Reconstruction and Development / The World Bank; 2017 Nov 3. Chapter 12. In: Holmes KK, Bertozzi S, Bloom BR, Jha P, editors. Major Infectious Diseases. 3rd edition. Washington (DC): The International Bank for Reconstruction and Development / The World Bank; 2017 Nov 3. Chapter 12. PMID: 30212099 Free Books & Documents. Review.
An additional 18 countries reduced incidence by more than 50 percent (WHO 2015e), also achieving target 6C of the Millennium Development Goals, which called for halting and beginning to reverse the global incidence of malaria by 2015. ...
An additional 18 countries reduced incidence by more than 50 percent (WHO 2015e), also achieving target 6C of the Millennium Development Goa …
Emodin reduces Breast Cancer Lung Metastasis by suppressing Macrophage-induced Breast Cancer Cell Epithelial-mesenchymal transition and Cancer Stem Cell formation.
Liu Q, Hodge J, Wang J, Wang Y, Wang L, Singh U, Li Y, Yao Y, Wang D, Ai W, Nagarkatti P, Chen H, Xu P, Murphy EA, Fan D. Liu Q, et al. Theranostics. 2020 Jul 9;10(18):8365-8381. doi: 10.7150/thno.45395. eCollection 2020. Theranostics. 2020. PMID: 32724475 Free PMC article.
Since tumor-associated macrophages (TAMs) also affect epithelial mesenchymal-transition (EMT) and cancer stem cell (CSC) formation, here we aimed to test if emodin as a neoadjuvant therapy halts breast cancer metastasis by attenuating TAM-induced EMT and CSC formation of b …
Since tumor-associated macrophages (TAMs) also affect epithelial mesenchymal-transition (EMT) and cancer stem cell (CSC) formation, here we …
243 results
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