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Early life adversity targets the transcriptional signature of hippocampal NG2+ glia and affects voltage gated sodium (Nav) channels properties.
Treccani G, Yigit H, Lingner T, Schleuβner V, Mey F, van der Kooij MA, Wennström M, Herzog DP, Linke M, Fricke M, Schmeisser MJ, Wegener G, Mittmann T, Trotter J, Müller MB. Treccani G, et al. Among authors: yigit h. Neurobiol Stress. 2021 May 14;15:100338. doi: 10.1016/j.ynstr.2021.100338. eCollection 2021 Nov. Neurobiol Stress. 2021. PMID: 34095364 Free PMC article.
NG2 plays a role in neuroinflammation but is not expressed by immune cells.
Kitic M, Karram K, Israel N, Yogev N, Lacher SM, Tang Y, Yigit H, Bauer J, Wanke F, Knezovic A, Trotter J, Kurschus FC, Waisman A. Kitic M, et al. Among authors: yigit h. Acta Neuropathol. 2017 Aug;134(2):325-327. doi: 10.1007/s00401-017-1735-5. Epub 2017 May 31. Acta Neuropathol. 2017. PMID: 28567522 No abstract available.