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A familiar study on self-limited childhood epilepsy patients using hIPSC-derived neurons shows a bias towards immaturity at the morphological, electrophysiological and gene expression levels.
Casalia ML, Casabona JC, García C, Cavaliere Candedo V, Quintá HR, Farías MI, Gonzalez J, Gonzalez Morón D, Córdoba M, Consalvo D, Mostoslavsky G, Urbano FJ, Pasquini J, Murer MG, Rela L, Kauffman MA, Pitossi FJ. Casalia ML, et al. Among authors: quinta hr. Stem Cell Res Ther. 2021 Nov 25;12(1):590. doi: 10.1186/s13287-021-02658-2. Stem Cell Res Ther. 2021. PMID: 34823607 Free PMC article.