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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 14
2003 27
2004 21
2005 19
2006 27
2007 35
2008 18
2009 27
2010 17
2011 24
2012 22
2013 31
2014 28
2015 22
2016 30
2017 32
2018 33
2019 25
2020 38
2021 31
2022 27
2023 26
2024 1

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504 results

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Page 1
Molecular mechanisms of thalidomide and its derivatives.
Ito T, Handa H. Ito T, et al. Among authors: handa h. Proc Jpn Acad Ser B Phys Biol Sci. 2020;96(6):189-203. doi: 10.2183/pjab.96.016. Proc Jpn Acad Ser B Phys Biol Sci. 2020. PMID: 32522938 Free PMC article.
Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma.
Moreau P, Masszi T, Grzasko N, Bahlis NJ, Hansson M, Pour L, Sandhu I, Ganly P, Baker BW, Jackson SR, Stoppa AM, Simpson DR, Gimsing P, Palumbo A, Garderet L, Cavo M, Kumar S, Touzeau C, Buadi FK, Laubach JP, Berg DT, Lin J, Di Bacco A, Hui AM, van de Velde H, Richardson PG; TOURMALINE-MM1 Study Group. Moreau P, et al. N Engl J Med. 2016 Apr 28;374(17):1621-34. doi: 10.1056/NEJMoa1516282. N Engl J Med. 2016. PMID: 27119237 Free article. Clinical Trial.
A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.
Matyskiela ME, Lu G, Ito T, Pagarigan B, Lu CC, Miller K, Fang W, Wang NY, Nguyen D, Houston J, Carmel G, Tran T, Riley M, Nosaka L, Lander GC, Gaidarova S, Xu S, Ruchelman AL, Handa H, Carmichael J, Daniel TO, Cathers BE, Lopez-Girona A, Chamberlain PP. Matyskiela ME, et al. Among authors: handa h. Nature. 2016 Jul 14;535(7611):252-7. doi: 10.1038/nature18611. Epub 2016 Jun 22. Nature. 2016. PMID: 27338790
[Multiple myeloma].
Handa H. Handa H. Rinsho Ketsueki. 2014 Feb;55(2):201-12. Rinsho Ketsueki. 2014. PMID: 24598188 Review. Japanese. No abstract available.
Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs.
Chamberlain PP, Lopez-Girona A, Miller K, Carmel G, Pagarigan B, Chie-Leon B, Rychak E, Corral LG, Ren YJ, Wang M, Riley M, Delker SL, Ito T, Ando H, Mori T, Hirano Y, Handa H, Hakoshima T, Daniel TO, Cathers BE. Chamberlain PP, et al. Among authors: handa h. Nat Struct Mol Biol. 2014 Sep;21(9):803-9. doi: 10.1038/nsmb.2874. Epub 2014 Aug 10. Nat Struct Mol Biol. 2014. PMID: 25108355
Molecular mechanisms of cereblon-based drugs.
Asatsuma-Okumura T, Ito T, Handa H. Asatsuma-Okumura T, et al. Among authors: handa h. Pharmacol Ther. 2019 Oct;202:132-139. doi: 10.1016/j.pharmthera.2019.06.004. Epub 2019 Jun 14. Pharmacol Ther. 2019. PMID: 31202702 Review.
[Cereblon as a primary target of IMiDs].
Ito T, Handa H. Ito T, et al. Among authors: handa h. Rinsho Ketsueki. 2019;60(9):1013-1019. doi: 10.11406/rinketsu.60.1013. Rinsho Ketsueki. 2019. PMID: 31597822 Review. Japanese.
504 results