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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1866 1
1916 1
1929 1
1931 2
1939 1
1942 1
1945 3
1947 1
1948 14
1949 11
1950 8
1951 4
1952 11
1953 7
1954 5
1955 5
1956 6
1957 11
1958 17
1959 11
1960 11
1961 11
1962 36
1963 37
1964 49
1965 57
1966 38
1967 47
1968 34
1969 51
1970 78
1971 93
1972 111
1973 116
1974 116
1975 172
1976 186
1977 194
1978 195
1979 242
1980 275
1981 254
1982 253
1983 296
1984 328
1985 370
1986 419
1987 461
1988 555
1989 589
1990 581
1991 592
1992 676
1993 732
1994 792
1995 913
1996 1055
1997 1055
1998 1102
1999 1326
2000 1526
2001 1751
2002 1919
2003 2114
2004 2282
2005 2655
2006 2886
2007 3273
2008 5046
2009 5989
2010 6472
2011 6928
2012 7058
2013 6175
2014 6178
2015 6605
2016 6242
2017 6936
2018 7648
2019 8596
2020 10430
2021 11770
2022 4756
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127,082 results
Results by year
Filters applied: . Clear all The following term was not found in PubMed: Hsing-Chuan
Page 1
Heterotopic ossification.
Shehab D, Elgazzar AH, Collier BD. Shehab D, et al. J Nucl Med. 2002 Mar;43(3):346-53. J Nucl Med. 2002. PMID: 11884494 Free article. Review.
Heterotopic ossification (HO) is the presence of bone in soft tissue where bone normally does not exist. ...Before therapy begins, bone scanning may be requested to confirm the diagnosis of HO. In addition, surgical resection of HO is used to preserve joint m …
Heterotopic ossification (HO) is the presence of bone in soft tissue where bone normally does not exist. ...Before therapy begins, bo …
Heterotopic ossification: a systematic review.
Edwards DS, Clasper JC. Edwards DS, et al. J R Army Med Corps. 2015 Dec;161(4):315-21. doi: 10.1136/jramc-2014-000277. Epub 2014 Jul 11. J R Army Med Corps. 2015. PMID: 25015927 Review.
Heterotopic ossification (HO) is the formation of mature lamellar bone in extraskeletal soft tissues. ...A systematic review in PubMed and the Cochrane Database identified research articles related to HO to illustrate the military problem of HO and its manage …
Heterotopic ossification (HO) is the formation of mature lamellar bone in extraskeletal soft tissues. ...A systematic review in PubMe …
HO in pregnancy.
Bainbridge SA, Smith GN. Bainbridge SA, et al. Free Radic Biol Med. 2005 Apr 15;38(8):979-88. doi: 10.1016/j.freeradbiomed.2004.11.002. Free Radic Biol Med. 2005. PMID: 15780756 Review.
In this review the role of HO, and its catalytic products, will be examined in the context of pregnancy. The different isoforms of the HO enzyme (HO-1, HO-2, HO-3) have been localized throughout placental tissue, and have been shown to be physio …
In this review the role of HO, and its catalytic products, will be examined in the context of pregnancy. The different isoforms of th …
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors.
Intagliata S, Salerno L, Ciaffaglione V, Leonardi C, Fallica AN, Carota G, Amata E, Marrazzo A, Pittalà V, Romeo G. Intagliata S, et al. Eur J Med Chem. 2019 Dec 1;183:111703. doi: 10.1016/j.ejmech.2019.111703. Epub 2019 Sep 17. Eur J Med Chem. 2019. PMID: 31550661 Review.
Among the different HO isoforms, HO-2 stands out for its neuroprotective properties and modulatory activity in male reproduction. ...To the best of our knowledge, among HO-2 inhibitors, clemizole derivatives are the most selective HO-2 inhibitors repor …
Among the different HO isoforms, HO-2 stands out for its neuroprotective properties and modulatory activity in male reproducti …
Clinical Significance of Heme Oxygenase 1 in Tumor Progression.
Nitti M, Ivaldo C, Traverso N, Furfaro AL. Nitti M, et al. Antioxidants (Basel). 2021 May 17;10(5):789. doi: 10.3390/antiox10050789. Antioxidants (Basel). 2021. PMID: 34067625 Free PMC article. Review.
Moreover, evidence from cancer biopsies highlights the possible correlation between HO-1 expression, pathological features, and clinical outcome. Indeed, high levels of HO-1 in tumor specimens often correlate with reduced survival rates. ...However, contrasting evid …
Moreover, evidence from cancer biopsies highlights the possible correlation between HO-1 expression, pathological features, and clini …
A focus on heme oxygenase-1 (HO-1) inhibitors.
Pittalà V, Salerno L, Romeo G, Modica MN, Siracusa MA. Pittalà V, et al. Curr Med Chem. 2013;20(30):3711-32. doi: 10.2174/0929867311320300003. Curr Med Chem. 2013. PMID: 23746277 Review.
HO exists in two distinct, catalytically active isoforms: HO-1 and HO-2. HO-1 is an inducible 32-kDa protein, while HO-2 is a constitutively synthesized 36-kDa protein and generally is unresponsive to any of the inducers of HO-1. ...
HO exists in two distinct, catalytically active isoforms: HO-1 and HO-2. HO-1 is an inducible 32-kDa protein, wh
Heme oxygenase-1: emerging target of cancer therapy.
Chau LY. Chau LY. J Biomed Sci. 2015 Mar 21;22(1):22. doi: 10.1186/s12929-015-0128-0. J Biomed Sci. 2015. PMID: 25885228 Free PMC article. Review.
HO-1 is highly induced in various disease states, including cancer. ...Although HO-1 is an endoplasmic reticulum resident protein, HO-1 nuclear localization is evident in tumor cells of cancer tissues. ...
HO-1 is highly induced in various disease states, including cancer. ...Although HO-1 is an endoplasmic reticulum resident prot
The expression, function and targeting of haem oxygenase-1 in cancer.
Hjortsø MD, Andersen MH. Hjortsø MD, et al. Curr Cancer Drug Targets. 2014;14(4):337-47. doi: 10.2174/1568009614666140320111306. Curr Cancer Drug Targets. 2014. PMID: 24655000 Review.
Consequently, several anticancer strategies aim at targeting HO-1. The inhibition of HO-1 may cause tumour cells to become more sensitive to chemotherapy and radiation therapy. ...Immunological targeting of HO-1 might represent an interesting approach, as epi …
Consequently, several anticancer strategies aim at targeting HO-1. The inhibition of HO-1 may cause tumour cells to become mor …
Signaling function of heme oxygenase proteins.
Dennery PA. Dennery PA. Antioxid Redox Signal. 2014 Apr 10;20(11):1743-53. doi: 10.1089/ars.2013.5674. Epub 2014 Feb 28. Antioxid Redox Signal. 2014. PMID: 24180238 Free PMC article. Review.
CRITICAL ISSUES: The signaling functions of HO-1 may have particular relevance in clinical circumstances, including cancer, as redistribution of HO-1 into the nuclear compartment is observed with cancer progression and metastasis. In addition, along with oxidative s …
CRITICAL ISSUES: The signaling functions of HO-1 may have particular relevance in clinical circumstances, including cancer, as redist …
The heme oxygenase system and oral diseases.
Fan W, Huang F, Zhu X, Li D, Fu S, He H. Fan W, et al. Oral Dis. 2011 Apr;17(3):252-7. doi: 10.1111/j.1601-0825.2010.01732.x. Epub 2010 Sep 23. Oral Dis. 2011. PMID: 20860760 Review.
Oral Diseases (2011) 17, 252-257 Heme oxygenase (HO) system catabolizes heme into three products: carbon monoxide (CO), biliverdin/bilirubin and free iron, which consists of three forms identified to date: the oxidative stress-inducible protein HO-1 and the constitu …
Oral Diseases (2011) 17, 252-257 Heme oxygenase (HO) system catabolizes heme into three products: carbon monoxide (CO), biliverdin/bi …
127,082 results
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