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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1943 1
1947 2
1950 1
1951 1
1953 1
1954 3
1955 1
1956 3
1957 5
1958 8
1959 8
1960 4
1961 9
1962 13
1963 14
1964 18
1965 19
1966 23
1967 19
1968 32
1969 39
1970 40
1971 50
1972 60
1973 97
1974 79
1975 112
1976 164
1977 189
1978 185
1979 236
1980 229
1981 277
1982 288
1983 352
1984 361
1985 406
1986 447
1987 504
1988 527
1989 678
1990 686
1991 910
1992 1380
1993 1607
1994 1881
1995 1990
1996 2283
1997 2543
1998 2897
1999 3491
2000 4170
2001 5195
2002 5654
2003 6299
2004 6756
2005 6860
2006 6914
2007 7701
2008 8995
2009 9502
2010 10427
2011 11435
2012 12191
2013 12133
2014 12936
2015 13763
2016 13785
2017 13944
2018 14080
2019 14330
2020 15583
2021 3538
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217,084 results
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Filters applied: . Clear all The following term was not found in PubMed: Huidae
Page 1
Did you mean suidae cho (1,735 results)?
Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Synthesis.
Reinhart D, Damjanovic L, Kaisermayer C, Sommeregger W, Gili A, Gasselhuber B, Castan A, Mayrhofer P, Grünwald-Gruber C, Kunert R. Reinhart D, et al. Biotechnol J. 2019 Mar;14(3):e1700686. doi: 10.1002/biot.201700686. Epub 2018 Jun 11. Biotechnol J. 2019. PMID: 29701329
Chinese hamster ovary (CHO) cells comprise a variety of lineages including CHO-DXB11, CHO-K1, CHO-DG44, and CHO-S. ...However, not much literature is available about the influence of genetic differences of CHO on the performance of biopro …
Chinese hamster ovary (CHO) cells comprise a variety of lineages including CHO-DXB11, CHO-K1, CHO-DG44, and C
The art of CHO cell engineering: A comprehensive retrospect and future perspectives.
Fischer S, Handrick R, Otte K. Fischer S, et al. Biotechnol Adv. 2015 Dec;33(8):1878-96. doi: 10.1016/j.biotechadv.2015.10.015. Epub 2015 Oct 31. Biotechnol Adv. 2015. PMID: 26523782 Review.
Chinese hamster ovary (CHO) cells represent the most frequently applied host cell system for industrial manufacturing of recombinant protein therapeutics. CHO cells are capable of producing high quality biologics exhibiting human-like post-translational modification …
Chinese hamster ovary (CHO) cells represent the most frequently applied host cell system for industrial manufacturing of recombinant …
CHO-Omics Review: The Impact of Current and Emerging Technologies on Chinese Hamster Ovary Based Bioproduction.
Stolfa G, Smonskey MT, Boniface R, Hachmann AB, Gulde P, Joshi AD, Pierce AP, Jacobia SJ, Campbell A. Stolfa G, et al. Biotechnol J. 2018 Mar;13(3):e1700227. doi: 10.1002/biot.201700227. Epub 2017 Nov 15. Biotechnol J. 2018. PMID: 29072373 Review.
CHO cells are the most prevalent platform for modern bio-therapeutic production. Currently, there are several CHO cell lines used in bioproduction with distinct characteristics and unique genotypes and phenotypes. ...
CHO cells are the most prevalent platform for modern bio-therapeutic production. Currently, there are several CHO cell lines u
Cell engineering and cultivation of chinese hamster ovary (CHO) cells.
Omasa T, Onitsuka M, Kim WD. Omasa T, et al. Curr Pharm Biotechnol. 2010 Apr;11(3):233-40. doi: 10.2174/138920110791111960. Curr Pharm Biotechnol. 2010. PMID: 20210750 Review.
The CHO-based cultivation process is well established and is a general platform of therapeutic antibody production. ...This review provides an overview of the industrial production of therapeutic proteins using a CHO cell expression system....
The CHO-based cultivation process is well established and is a general platform of therapeutic antibody production. ...This review pr …
The fickle CHO: a review of the causes, implications, and potential alleviation of the CHO cell line instability problem.
Dahodwala H, Lee KH. Dahodwala H, et al. Curr Opin Biotechnol. 2019 Dec;60:128-137. doi: 10.1016/j.copbio.2019.01.011. Epub 2019 Feb 28. Curr Opin Biotechnol. 2019. PMID: 30826670 Review.
Chinese hamster ovary (CHO) cell-based bioproduction of recombinant proteins can now routinely achieve >5 g/L titers in fed-batches. This progress is partly due to the rapid adaptability of CHO cells to various genetic manipulations and changing process condition …
Chinese hamster ovary (CHO) cell-based bioproduction of recombinant proteins can now routinely achieve >5 g/L titers in fed-batche …
A high density CHO-S transient transfection system: Comparison of ExpiCHO and Expi293.
Jain NK, Barkowski-Clark S, Altman R, Johnson K, Sun F, Zmuda J, Liu CY, Kita A, Schulz R, Neill A, Ballinger R, Patel R, Liu J, Mpanda A, Huta B, Chiou H, Voegtli W, Panavas T. Jain NK, et al. Protein Expr Purif. 2017 Jun;134:38-46. doi: 10.1016/j.pep.2017.03.018. Epub 2017 Mar 23. Protein Expr Purif. 2017. PMID: 28342833
Chinese Hamster Ovary (CHO) cells are the principal mammalian host used for stable cell line generation and biotherapeutic protein production. ...Therefore, it is potentially advantageous to keep the host cell type consistent throughout drug discovery and development. To t …
Chinese Hamster Ovary (CHO) cells are the principal mammalian host used for stable cell line generation and biotherapeutic protein pr …
Carbohydrate intake during exercise and performance.
Jeukendrup AE. Jeukendrup AE. Nutrition. 2004 Jul-Aug;20(7-8):669-77. doi: 10.1016/j.nut.2004.04.017. Nutrition. 2004. PMID: 15212750 Review.
An analysis of all studies available shows that a single CHO ingested during exercise will be oxidized at rates up to about 1 g/min, even when large amounts of CHO are ingested. Combinations of CHO that use different intestinal transporters for absorption (e. …
An analysis of all studies available shows that a single CHO ingested during exercise will be oxidized at rates up to about 1 g/min, …
Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells.
Fan L, Kadura I, Krebs LE, Hatfield CC, Shaw MM, Frye CC. Fan L, et al. Biotechnol Bioeng. 2012 Apr;109(4):1007-15. doi: 10.1002/bit.24365. Epub 2011 Nov 21. Biotechnol Bioeng. 2012. PMID: 22068567
Although Chinese hamster ovary (CHO) cells, with their unique characteristics, have become a major workhorse for the manufacture of therapeutic recombinant proteins, one of the major challenges in CHO cell line generation (CLG) is how to efficiently identify those r …
Although Chinese hamster ovary (CHO) cells, with their unique characteristics, have become a major workhorse for the manufacture of t …
An Online Compendium of CHO RNA-Seq Data Allows Identification of CHO Cell Line-Specific Transcriptomic Signatures.
Singh A, Kildegaard HF, Andersen MR. Singh A, et al. Biotechnol J. 2018 Oct;13(10):e1800070. doi: 10.1002/biot.201800070. Epub 2018 Jul 5. Biotechnol J. 2018. PMID: 29762913
To address these challenges, a compendium of 23 RNA-Seq studies from public and in-house data on CHO cell lines, i.e., CHO-S, CHO-K1, and DG44 is compiled. Significantly differentially expressed (DE) genes particularly related to subcellular structure and mac …
To address these challenges, a compendium of 23 RNA-Seq studies from public and in-house data on CHO cell lines, i.e., CHO-S, …
Optimized Selection Marker and CHO Host Cell Combinations for Generating High Monoclonal Antibody Producing Cell Lines.
Yeo JHM, Ho SCL, Mariati M, Koh E, Tay SJ, Woen S, Zhang P, Yang Y. Yeo JHM, et al. Biotechnol J. 2017 Dec;12(12). doi: 10.1002/biot.201700175. Epub 2017 Oct 23. Biotechnol J. 2017. PMID: 29090854
The high producing CHO K1 pools and clones generated using ARG exhibit better production stability than the amplified high producing CHO DG44 pools and clones. Loss of expression for the CHO K1 cell lines is due to loss of gene copies while for CHO DG4 …
The high producing CHO K1 pools and clones generated using ARG exhibit better production stability than the amplified high producing …
217,084 results
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