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64 results

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Page 1
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states.
Leng K, Rose IVL, Kim H, Xia W, Romero-Fernandez W, Rooney B, Koontz M, Li E, Ao Y, Wang S, Krawczyk M, Tcw J, Goate A, Zhang Y, Ullian EM, Sofroniew MV, Fancy SPJ, Schrag MS, Lippmann ES, Kampmann M. Leng K, et al. Among authors: kim h. Nat Neurosci. 2022 Nov;25(11):1528-1542. doi: 10.1038/s41593-022-01180-9. Epub 2022 Oct 27. Nat Neurosci. 2022. PMID: 36303069 Free PMC article.
Durvalumab or placebo plus gemcitabine and cisplatin in participants with advanced biliary tract cancer (TOPAZ-1): updated overall survival from a randomised phase 3 study.
Oh DY, He AR, Bouattour M, Okusaka T, Qin S, Chen LT, Kitano M, Lee CK, Kim JW, Chen MH, Suksombooncharoen T, Ikeda M, Lee MA, Chen JS, Potemski P, Burris HA 3rd, Ostwal V, Tanasanvimon S, Morizane C, Zaucha RE, McNamara MG, Avallone A, Cundom JE, Breder V, Tan B, Shimizu S, Tougeron D, Evesque L, Petrova M, Zhen DB, Gillmore R, Gupta VG, Dayyani F, Park JO, Buchschacher GL Jr, Rey F, Kim H, Wang J, Morgan C, Rokutanda N, Żotkiewicz M, Vogel A, Valle JW. Oh DY, et al. Among authors: kim h. Lancet Gastroenterol Hepatol. 2024 Aug;9(8):694-704. doi: 10.1016/S2468-1253(24)00095-5. Epub 2024 May 29. Lancet Gastroenterol Hepatol. 2024. PMID: 38823398 Clinical Trial.
Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin.
Kim H, Leng K, Park J, Sorets AG, Kim S, Shostak A, Embalabala RJ, Mlouk K, Katdare KA, Rose IVL, Sturgeon SM, Neal EH, Ao Y, Wang S, Sofroniew MV, Brunger JM, McMahon DG, Schrag MS, Kampmann M, Lippmann ES. Kim H, et al. Nat Commun. 2022 Nov 2;13(1):6581. doi: 10.1038/s41467-022-34412-4. Nat Commun. 2022. PMID: 36323693 Free PMC article.
Biofunctionalized gelatin hydrogels support development and maturation of iPSC-derived cortical organoids.
Kjar A, Haschert MR, Zepeda JC, Simmons AJ, Yates A, Chavarria D, Fernandez M, Robertson G, Abdulrahman AM, Kim H, Marguerite NT, Moen RK, Drake LE, Curry CW, O'Grady BJ, Gama V, Lau KS, Grueter B, Brunger JM, Lippmann ES. Kjar A, et al. Among authors: kim h. Cell Rep. 2024 Nov 26;43(11):114874. doi: 10.1016/j.celrep.2024.114874. Epub 2024 Oct 17. Cell Rep. 2024. PMID: 39423129 Free PMC article.
IQGAP2 regulates blood-brain barrier immune dynamics.
Katdare KA, Kjar A, O'Brown NM, Neal EH, Sorets AG, Shostak A, Romero-Fernandez W, Kwiatkowski AJ, Mlouk K, Kim H, Cowell RP, Schwensen KR, Horner KB, Wilson JT, Schrag MS, Megason SG, Lippmann ES. Katdare KA, et al. Among authors: kim h. bioRxiv [Preprint]. 2024 Apr 12:2023.02.07.527394. doi: 10.1101/2023.02.07.527394. bioRxiv. 2024. Update in: iScience. 2025 Feb 11;28(3):111994. doi: 10.1016/j.isci.2025.111994. PMID: 38645082 Free PMC article. Updated. Preprint.
Phosphorylation of an RNA-Binding Protein Rck/Me31b by Hippo Is Essential for Adipose Tissue Aging.
Yeom E, Mun H, Lim J, Chun YL, Min KW, Lambert J, Cowart LA, Pierce JS, Ogretmen B, Cho JH, Chang JH, Buchan JR, Pitt J, Kaeberlein M, Kang SU, Kwon ES, Ko S, Choi KM, Lee YS, Ha YS, Kim SJ, Lee KP, Kim HS, Yang SY, Shin CH, Yoon JH, Lee KS. Yeom E, et al. Aging Cell. 2025 Mar 11:e70022. doi: 10.1111/acel.70022. Online ahead of print. Aging Cell. 2025. PMID: 40070010 Free article.
IQGAP2 regulates blood-brain barrier immune dynamics.
Katdare KA, Kjar A, O'Brown NM, Neal EH, Sorets AG, Shostak A, Romero-Fernandez W, Kwiatkowski AJ, Mlouk K, Kim H, Cowell RP, Schwensen KR, Carvajal Tapia CO, Venslovaite G, Horner KB, Wilson JT, Schrag MS, Megason SG, Lippmann ES. Katdare KA, et al. Among authors: kim h. iScience. 2025 Feb 11;28(3):111994. doi: 10.1016/j.isci.2025.111994. eCollection 2025 Mar 21. iScience. 2025. PMID: 40071147 Free PMC article.
64 results