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Genetics-nutrition interactions control diurnal enhancer-promoter dynamics and liver lipid metabolism.
Zhou D, Chen Y, Liu P, Zhu K, Holder-Haynes J, Lloyd SJ, La CM, Astapova II, Choa S, Xiong Y, Bae H, Aguilar M, Yang H, An YA, Sun Z, Herman MA, Gao X, Pei L, Jang C, Rabinowitz JD, Mattar SG, Zhang Y, Guan D. Zhou D, et al. Among authors: astapova ii. Cell Metab. 2025 Oct 7;37(10):1961-1979.e7. doi: 10.1016/j.cmet.2025.07.010. Epub 2025 Aug 25. Cell Metab. 2025. PMID: 40858101
Intestinal, but not hepatic, ChREBP is required for fructose tolerance.
Kim M, Astapova II, Flier SN, Hannou SA, Doridot L, Sargsyan A, Kou HH, Fowler AJ, Liang G, Herman MA. Kim M, et al. Among authors: astapova ii. JCI Insight. 2017 Dec 21;2(24):e96703. doi: 10.1172/jci.insight.96703. JCI Insight. 2017. PMID: 29263303 Free PMC article.