The stress response regulator HSF1 modulates natural killer cell anti-tumour immunity.
Hockemeyer K, Sakellaropoulos T, Chen X, Ivashkiv O, Sirenko M, Zhou H, Gambi G, Battistello E, Avrampou K, Sun Z, Guillamot M, Chiriboga L, Jour G, Dolgalev I, Corrigan K, Bhatt K, Osman I, Tsirigos A, Kourtis N, Aifantis I.
Hockemeyer K, et al.
Nat Cell Biol. 2024 Oct;26(10):1734-1744. doi: 10.1038/s41556-024-01490-z. Epub 2024 Sep 2.
Nat Cell Biol. 2024.
PMID: 39223375
Diverse cellular insults converge on activation of the heat shock factor 1 (HSF1), which regulates the proteotoxic stress response to maintain protein homoeostasis. HSF1 regulates numerous gene programmes beyond the proteotoxic stress response in a cell-type- and context-s …
Diverse cellular insults converge on activation of the heat shock factor 1 (HSF1), which regulates the proteotoxic stress response to mai …