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Page 1
Binding studies of a large antiviral polyamide to a natural HPV sequence.
He G, Vasilieva E, Harris GD Jr, Koeller KJ, Bashkin JK, Dupureur CM. He G, et al. Biochimie. 2014 Jul;102:83-91. doi: 10.1016/j.biochi.2014.02.011. Epub 2014 Feb 26. Biochimie. 2014. PMID: 24582833 Free PMC article.
PA1 is a large hairpin polyamide (dImPyPy-beta-PyPyPy-gamma-PyPy-beta-PyPyPyPy-beta-Ta; Py = pyrrole, Im = imidazole, beta = beta alanine) that targets the sequence 5'-WWGWWWWWWW-3' (W = A or T) and is effective in eliminating HPV16 in cell culture (Edwards, T. G., Koeller, K. …
PA1 is a large hairpin polyamide (dImPyPy-beta-PyPyPy-gamma-PyPy-beta-PyPyPyPy-beta-Ta; Py = pyrrole, Im = imidazole, beta = beta alanine) t …
Gut microbiota strain richness is species specific and affects engraftment.
Chen-Liaw A, Aggarwala V, Mogno I, Haifer C, Li Z, Eggers J, Helmus D, Hart A, Wehkamp J, Lamousé-Smith ESN, Kerby RL, Rey FE, Colombel JF, Kamm MA, Olle B, Norman JM, Menon R, Watson AR, Crossette E, Terveer EM, Keller JJ, Borody TJ, Grinspan A, Paramsothy S, Kaakoush NO, Dubinsky MC, Faith JJ. Chen-Liaw A, et al. Nature. 2025 Jan;637(8045):422-429. doi: 10.1038/s41586-024-08242-x. Epub 2024 Nov 27. Nature. 2025. PMID: 39604726
Age-related patterns of microbial dysbiosis in multiplex inflammatory bowel disease families.
Jacobs JP, Spencer EA, Helmus DS, Yang JC, Lagishetty V, Bongers G, Britton G, Gettler K, Reyes-Mercedes P, Hu J, Hart A, Lamousé-Smith E, Wehkamp J, Landers C, Debbas P, Torres J, Colombel JF, Cho J, Peter I, Faith J, Braun J, Dubinsky M. Jacobs JP, et al. Gut. 2024 Nov 11;73(12):1953-1964. doi: 10.1136/gutjnl-2024-332475. Gut. 2024. PMID: 39122361
The metaRbolomics Toolbox in Bioconductor and beyond.
Stanstrup J, Broeckling CD, Helmus R, Hoffmann N, Mathé E, Naake T, Nicolotti L, Peters K, Rainer J, Salek RM, Schulze T, Schymanski EL, Stravs MA, Thévenot EA, Treutler H, Weber RJM, Willighagen E, Witting M, Neumann S. Stanstrup J, et al. Metabolites. 2019 Sep 23;9(10):200. doi: 10.3390/metabo9100200. Metabolites. 2019. PMID: 31548506 Free PMC article. Review.
Interactions of two large antiviral polyamides with the long control region of HPV16.
Vasilieva E, Niederschulte J, Song Y, Harris GD Jr, Koeller KJ, Liao P, Bashkin JK, Dupureur CM. Vasilieva E, et al. Biochimie. 2016 Aug;127:103-14. doi: 10.1016/j.biochi.2016.04.022. Epub 2016 May 4. Biochimie. 2016. PMID: 27155361 Free PMC article.
PA1 and PA25 are large hairpin polyamides that are effective in nearly eliminating HPV16 episomes (DNA) in cell culture, and PA25 has broad spectrum activity against three cancer-causing forms of HPV (Edwards, T. G., Koeller, K. J., Slomczynska, U., Fok, K., Helmus, …
PA1 and PA25 are large hairpin polyamides that are effective in nearly eliminating HPV16 episomes (DNA) in cell culture, and PA25 has broad …
Selective IgA2 deficiency in a patient with small intestinal Crohn's disease.
Canales-Herrerias P, Garcia-Carmona Y, Shang J, Meringer H, Yee DS, Radigan L, Buta S, Martinez-Delgado G, Tankelevich M, Helmus D, Dubinsky M, Everts-van der Mind A, Dervieux T, Bogunovic D, Colombel JF, Brenchley JM, Faith J, Cunningham-Rundles C, Cerutti A, Mehandru S. Canales-Herrerias P, et al. J Clin Invest. 2023 Jun 15;133(12):e167742. doi: 10.1172/JCI167742. J Clin Invest. 2023. PMID: 37129981 Free PMC article. No abstract available.
The 2015 Static-99R: Alternative Recidivism Tables for High-Risk Offenders.
Elwood RW, Kelley SM, Mundt JC. Elwood RW, et al. Int J Offender Ther Comp Criminol. 2017 Oct;61(14):1593-1605. doi: 10.1177/0306624X15623803. Epub 2016 Jan 11. Int J Offender Ther Comp Criminol. 2017. PMID: 26758206
The Static-99R is an actuarial scale that is commonly used to assess the recidivism risk of male sex offenders. Hanson, Thornton, Helmus, and Babchishin recently revised the Static-99R norms based on revised analyses that excluded the large Bridgewater sample. ...
The Static-99R is an actuarial scale that is commonly used to assess the recidivism risk of male sex offenders. Hanson, Thornton, Helmus …
77 results