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Year Number of Results
2015 1
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2020 6
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A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer.
Ott PA, Hu-Lieskovan S, Chmielowski B, Govindan R, Naing A, Bhardwaj N, Margolin K, Awad MM, Hellmann MD, Lin JJ, Friedlander T, Bushway ME, Balogh KN, Sciuto TE, Kohler V, Turnbull SJ, Besada R, Curran RR, Trapp B, Scherer J, Poran A, Harjanto D, Barthelme D, Ting YS, Dong JZ, Ware Y, Huang Y, Huang Z, Wanamaker A, Cleary LD, Moles MA, Manson K, Greshock J, Khondker ZS, Fritsch E, Rooney MS, DeMario M, Gaynor RB, Srinivasan L. Ott PA, et al. Cell. 2020 Oct 15;183(2):347-362.e24. doi: 10.1016/j.cell.2020.08.053. Cell. 2020. PMID: 33064988 Free article. Clinical Trial.
Pegcetacoplan controls hemolysis in complement inhibitor-naive patients with paroxysmal nocturnal hemoglobinuria.
Wong RSM, Navarro-Cabrera JR, Comia NS, Goh YT, Idrobo H, Kongkabpan D, Gómez-Almaguer D, Al-Adhami M, Ajayi T, Alvarenga P, Savage J, Deschatelets P, Francois C, Grossi F, Dumagay T. Wong RSM, et al. Blood Adv. 2023 Jun 13;7(11):2468-2478. doi: 10.1182/bloodadvances.2022009129. Blood Adv. 2023. PMID: 36848639 Free PMC article. Clinical Trial.
Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma.
Hu Z, Leet DE, Allesøe RL, Oliveira G, Li S, Luoma AM, Liu J, Forman J, Huang T, Iorgulescu JB, Holden R, Sarkizova S, Gohil SH, Redd RA, Sun J, Elagina L, Giobbie-Hurder A, Zhang W, Peter L, Ciantra Z, Rodig S, Olive O, Shetty K, Pyrdol J, Uduman M, Lee PC, Bachireddy P, Buchbinder EI, Yoon CH, Neuberg D, Pentelute BL, Hacohen N, Livak KJ, Shukla SA, Olsen LR, Barouch DH, Wucherpfennig KW, Fritsch EF, Keskin DB, Wu CJ, Ott PA. Hu Z, et al. Nat Med. 2021 Mar;27(3):515-525. doi: 10.1038/s41591-020-01206-4. Epub 2021 Jan 21. Nat Med. 2021. PMID: 33479501 Free PMC article.
A Cdk5-derived peptide inhibits Cdk5/p25 activity and improves neurodegenerative phenotypes.
Pao PC, Seo J, Lee A, Kritskiy O, Patnaik D, Penney J, Raju RM, Geigenmuller U, Silva MC, Lucente DE, Gusella JF, Dickerson BC, Loon A, Yu MX, Bula M, Yu M, Haggarty SJ, Tsai LH. Pao PC, et al. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2217864120. doi: 10.1073/pnas.2217864120. Epub 2023 Apr 12. Proc Natl Acad Sci U S A. 2023. PMID: 37043533 Free PMC article.
Machine learning based algorithms to impute PaO(2) from SpO(2) values and development of an online calculator.
Ren S, Zupetic JA, Tabary M, DeSensi R, Nouraie M, Lu X, Boyce RD, Lee JS. Ren S, et al. Sci Rep. 2022 May 17;12(1):8235. doi: 10.1038/s41598-022-12419-7. Sci Rep. 2022. PMID: 35581469 Free PMC article.
We created an online calculator using machine learning (ML) algorithms to impute the partial pressure of oxygen (PaO(2))/fraction of delivered oxygen (FiO(2)) ratio using the non-invasive peripheral saturation of oxygen (SpO(2)) and compared the accuracy of the ML models w …
We created an online calculator using machine learning (ML) algorithms to impute the partial pressure of oxygen (PaO(2))/fraction of …
Primary Hip Arthroscopy in Patients With Acetabular Dysplasia: A Systematic Review of Published Clinical Outcomes at Minimum 5-Year Follow-up.
Boos AM, Nagelli CV, Okoroha KR, Sierra RJ, Krych AJ, Hevesi M. Boos AM, et al. Am J Sports Med. 2024 Jul;52(8):2148-2158. doi: 10.1177/03635465231197177. Epub 2024 Feb 9. Am J Sports Med. 2024. PMID: 38333917
These findings suggest that hip dysplasia may not be an absolute contraindication for isolated hip arthroscopy and may serve as a viable intervention with consideration of staged future periacetabular osteotomy (PAO). Importantly, this review does not suggest that hip arth …
These findings suggest that hip dysplasia may not be an absolute contraindication for isolated hip arthroscopy and may serve as a viable int …
Natural History of the Dysplastic Hip Following Modern Periacetabular Osteotomy.
Wyles CC, Vargas JS, Heidenreich MJ, Mara KC, Peters CL, Clohisy JC, Trousdale RT, Sierra RJ. Wyles CC, et al. J Bone Joint Surg Am. 2019 May 15;101(10):932-938. doi: 10.2106/JBJS.18.00983. J Bone Joint Surg Am. 2019. PMID: 31094985 Clinical Trial.
The purpose of this multicenter cohort study was to delineate the long-term radiographic natural history of the dysplastic hip following PAO. METHODS: We evaluated all patients undergoing PAO from 1996 to 2012 at 3 academic institutions in the United States. Inclusi …
The purpose of this multicenter cohort study was to delineate the long-term radiographic natural history of the dysplastic hip following …
The Use of Combined Hip Arthroscopy and Periacetabular Osteotomy for Hip Dysplasia Is Increasing and Has Low Complication Rates.
Serna J, Furie K, Wong SE, Swarup I, Zhang AL, Diab M. Serna J, et al. Arthrosc Sports Med Rehabil. 2024 Mar 26;6(3):100929. doi: 10.1016/j.asmr.2024.100929. eCollection 2024 Jun. Arthrosc Sports Med Rehabil. 2024. PMID: 39006788 Free PMC article.
METHODS: International Classification of Diseases, Ninth and Tenth Revision, codes were used to query the PearlDiver Mariner database from January 2010 through January 2022 to identify patients aged 10 to 59 years who had a presenting diagnosis of HD and subsequently underwent (1 …
METHODS: International Classification of Diseases, Ninth and Tenth Revision, codes were used to query the PearlDiver Mariner database from J …
Unaddressed Cam Deformity Is Associated with Elevated Joint Contact Stress After Periacetabular Osteotomy.
Scott EJ, Thomas-Aitken HD, Glass N, Westermann R, Goetz JE, Willey MC. Scott EJ, et al. J Bone Joint Surg Am. 2018 Oct 17;100(20):e131. doi: 10.2106/JBJS.17.01631. J Bone Joint Surg Am. 2018. PMID: 30334890
Our purpose was to identify the relationship between cam deformity and joint contact stress after periacetabular osteotomy (PAO). We hypothesized that cam deformity is associated with an increase in peak joint contact stress after PAO. METHODS: This was a retrospect …
Our purpose was to identify the relationship between cam deformity and joint contact stress after periacetabular osteotomy (PAO). We …
20 results