Rifampicin as an example of beyond-rule-of-5 compound: Ionization beyond water and lipophilicity beyond octanol/water.
Eur J Pharm Sci. 2021 Jun 1;161:105802. doi: 10.1016/j.ejps.2021.105802. Epub 2021 Mar 11.
Eur J Pharm Sci. 2021.
PMID: 33716188