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2001 1
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SCID in Jack Russell terriers: a new animal model of DNA-PKcs deficiency.
Meek K, Kienker L, Dallas C, Wang W, Dark MJ, Venta PJ, Huie ML, Hirschhorn R, Bell T. Meek K, et al. J Immunol. 2001 Aug 15;167(4):2142-50. doi: 10.4049/jimmunol.167.4.2142. J Immunol. 2001. PMID: 11489998
We recently described the incidence of a SCID disease in a litter of Jack Russell terriers. In this study, we show that the molecular defect in these animals is faulty V(D)J recombination. ...
We recently described the incidence of a SCID disease in a litter of Jack Russell terriers. In this study, we show that the molecular …
DNA-PKcs mutations in dogs and horses: allele frequency and association with neoplasia.
Ding Q, Bramble L, Yuzbasiyan-Gurkan V, Bell T, Meek K. Ding Q, et al. Gene. 2002 Jan 23;283(1-2):263-9. doi: 10.1016/s0378-1119(01)00880-0. Gene. 2002. PMID: 11867233
Previously, spontaneous genetic immunodeficiencies in mice, Arabian foals, and recently in Jack Russell terriers have been ascribed to defects in DNA-PKcs (catalytic subunit of the DNA dependent protein kinase) expression. ...Here, we have ascertained the carrier frequency …
Previously, spontaneous genetic immunodeficiencies in mice, Arabian foals, and recently in Jack Russell terriers have been ascribed t …