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Page 1
Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.
Allesøe RL, Lundgaard AT, Hernández Medina R, Aguayo-Orozco A, Johansen J, Nissen JN, Brorsson C, Mazzoni G, Niu L, Biel JH, Leal Rodríguez C, Brasas V, Webel H, Benros ME, Pedersen AG, Chmura PJ, Jacobsen UP, Mari A, Koivula R, Mahajan A, Vinuela A, Tajes JF, Sharma S, Haid M, Hong MG, Musholt PB, De Masi F, Vogt J, Pedersen HK, Gudmundsdottir V, Jones A, Kennedy G, Bell J, Thomas EL, Frost G, Thomsen H, Hansen E, Hansen TH, Vestergaard H, Muilwijk M, Blom MT, 't Hart LM, Pattou F, Raverdy V, Brage S, Kokkola T, Heggie A, McEvoy D, Mourby M, Kaye J, Hattersley A, McDonald T, Ridderstråle M, Walker M, Forgie I, Giordano GN, Pavo I, Ruetten H, Pedersen O, Hansen T, Dermitzakis E, Franks PW, Schwenk JM, Adamski J, McCarthy MI, Pearson E, Banasik K, Rasmussen S, Brunak S; IMI DIRECT Consortium. Allesøe RL, et al. Nat Biotechnol. 2023 Mar;41(3):399-408. doi: 10.1038/s41587-022-01520-x. Epub 2023 Jan 2. Nat Biotechnol. 2023. PMID: 36593394 Free PMC article.
CoverM: read alignment statistics for metagenomics.
Aroney STN, Newell RJP, Nissen JN, Camargo AP, Tyson GW, Woodcroft BJ. Aroney STN, et al. Among authors: nissen jn. Bioinformatics. 2025 Mar 29;41(4):btaf147. doi: 10.1093/bioinformatics/btaf147. Bioinformatics. 2025. PMID: 40193404 Free PMC article.
Genome binning of viral entities from bulk metagenomics data.
Johansen J, Plichta DR, Nissen JN, Jespersen ML, Shah SA, Deng L, Stokholm J, Bisgaard H, Nielsen DS, Sørensen SJ, Rasmussen S. Johansen J, et al. Nat Commun. 2022 Feb 18;13(1):965. doi: 10.1038/s41467-022-28581-5. Nat Commun. 2022. PMID: 35181661 Free PMC article.
Experimental infection of pigs and ferrets with "pre-pandemic," human-adapted, and swine-adapted variants of the H1N1pdm09 influenza A virus reveals significant differences in viral dynamics and pathological manifestations.
Kristensen C, Laybourn HA, Crumpton JC, Martiny K, Webb A, Ryt-Hansen P, Trebbien R, Jensen HE, Nissen JN, Skovgaard K, Webby RJ, Larsen LE. Kristensen C, et al. Among authors: nissen jn. PLoS Pathog. 2023 Dec 4;19(12):e1011838. doi: 10.1371/journal.ppat.1011838. eCollection 2023 Dec. PLoS Pathog. 2023. PMID: 38048355 Free PMC article.
16 results