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Page 1
Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.
Elrick H, Peterson KA, Willis BJ, Lanza DG, Acar EF, Ryder EJ, Teboul L, Kasparek P, Birling MC, Adams DJ, Bradley A, Braun RE, Brown SD, Caulder A, Codner GF, DeMayo FJ, Dickinson ME, Doe B, Duddy G, Gertsenstein M, Goodwin LO, Hérault Y, Lintott LG, Lloyd KCK, Lorenzo I, Mackenzie M, Mallon AM, McKerlie C, Parkinson H, Ramirez-Solis R, Seavitt JR, Sedlacek R, Skarnes WC, Smedley D, Wells S, White JK, Wood JA; International Mouse Phenotyping Consortium; Murray SA, Heaney JD, Nutter LMJ. Elrick H, et al. Sci Rep. 2024 Sep 30;14(1):22626. doi: 10.1038/s41598-024-72418-8. Sci Rep. 2024. PMID: 39349521 Free PMC article.
Ablation of Gabra5 Influences Corticosterone Levels and Anxiety-like Behavior in Mice.
Syding LA, Kubik-Zahorodna A, Reguera DP, Nickl P, Hruskova B, Kralikova M, Kopkanova J, Novosadova V, Kasparek P, Prochazka J, Rozman J, Turecek R, Sedlacek R. Syding LA, et al. Among authors: kopkanova j. Genes (Basel). 2023 Jan 21;14(2):285. doi: 10.3390/genes14020285. Genes (Basel). 2023. PMID: 36833213 Free PMC article.
The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release.
Düsterhöft S, Kahveci-Türköz S, Wozniak J, Seifert A, Kasparek P, Ohm H, Liu S, Kopkanova J, Lokau J, Garbers C, Preisinger C, Sedlacek R, Freeman M, Ludwig A. Düsterhöft S, et al. Among authors: kopkanova j. Cell Mol Life Sci. 2021 Jun;78(11):5015-5040. doi: 10.1007/s00018-021-03845-3. Epub 2021 May 5. Cell Mol Life Sci. 2021. PMID: 33950315 Free PMC article.