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Exosomes induce and reverse monocrotaline-induced pulmonary hypertension in mice.
Aliotta JM, Pereira M, Wen S, Dooner MS, Del Tatto M, Papa E, Goldberg LR, Baird GL, Ventetuolo CE, Quesenberry PJ, Klinger JR. Aliotta JM, et al. Cardiovasc Res. 2016 Jun 1;110(3):319-30. doi: 10.1093/cvr/cvw054. Epub 2016 Mar 14. Cardiovasc Res. 2016. PMID: 26980205 Free PMC article.
EXOs from MCT-injured mice and patients with idiopathic pulmonary arterial hypertension (IPAH) contained increased levels of miRs-19b,-20a,-20b, and -145, whereas miRs isolated from MSC-EXOs had increased levels of anti-inflammatory, anti-proliferative miRs including miRs- …
EXOs from MCT-injured mice and patients with idiopathic pulmonary arterial hypertension (IPAH) contained increased levels of miRs-19b,-20