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Page 1
Editorial.
Demmers JAA. Demmers JAA. J Proteomics. 2022 Jun 30;262:104593. doi: 10.1016/j.jprot.2022.104593. Epub 2022 Apr 20. J Proteomics. 2022. PMID: 35483230 No abstract available.
An organoid-derived bronchioalveolar model for SARS-CoV-2 infection of human alveolar type II-like cells.
Lamers MM, van der Vaart J, Knoops K, Riesebosch S, Breugem TI, Mykytyn AZ, Beumer J, Schipper D, Bezstarosti K, Koopman CD, Groen N, Ravelli RBG, Duimel HQ, Demmers JAA, Verjans GMGM, Koopmans MPG, Muraro MJ, Peters PJ, Clevers H, Haagmans BL. Lamers MM, et al. Among authors: demmers jaa. EMBO J. 2021 Mar 1;40(5):e105912. doi: 10.15252/embj.2020105912. Epub 2021 Jan 11. EMBO J. 2021. PMID: 33283287 Free PMC article.
Transcription-coupled DNA-protein crosslink repair by CSB and CRL4CSA-mediated degradation.
van Sluis M, Yu Q, van der Woude M, Gonzalo-Hansen C, Dealy SC, Janssens RC, Somsen HB, Ramadhin AR, Dekkers DHW, Wienecke HL, Demmers JJPG, Raams A, Davó-Martínez C, Llerena Schiffmacher DA, van Toorn M, Häckes D, Thijssen KL, Zhou D, Lammers JG, Pines A, Vermeulen W, Pothof J, Demmers JAA, van den Berg DLC, Lans H, Marteijn JA. van Sluis M, et al. Among authors: demmers jaa. Nat Cell Biol. 2024 May;26(5):770-783. doi: 10.1038/s41556-024-01394-y. Epub 2024 Apr 10. Nat Cell Biol. 2024. PMID: 38600236 Free PMC article.
TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast Cancer.
Kortleve D, Hammerl D, van Brakel M, Wijers R, Roelofs D, Kroese K, Timmermans MM, Liao CY, Huang S, Trapman-Jansen A, Foekens R, Michaux J, de Beijer MTA, Buschow SI, Demmers JAA, Kok M, Danen EHJ, Bassani-Sternberg M, Martens JWM, Abbott RJM, Debets R. Kortleve D, et al. Among authors: demmers jaa. Cancer Discov. 2024 Dec 2;14(12):2450-2470. doi: 10.1158/2159-8290.CD-24-0168. Cancer Discov. 2024. PMID: 39172012 Free PMC article.
Different SWI/SNF complexes coordinately promote R-loop- and RAD52-dependent transcription-coupled homologous recombination.
Davó-Martínez C, Helfricht A, Ribeiro-Silva C, Raams A, Tresini M, Uruci S, van Cappellen WA, Taneja N, Demmers JAA, Pines A, Theil AF, Vermeulen W, Lans H. Davó-Martínez C, et al. Among authors: demmers jaa. Nucleic Acids Res. 2023 Sep 22;51(17):9055-9074. doi: 10.1093/nar/gkad609. Nucleic Acids Res. 2023. PMID: 37470997 Free PMC article.
Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2.
Pastoors D, Havermans M, Mulet-Lazaro R, Brian D, Noort W, Grasel J, Hoogenboezem R, Smeenk L, Demmers JAA, Milsom MD, Enver T, Groen RWJ, Bindels E, Delwel R. Pastoors D, et al. Among authors: demmers jaa. Sci Adv. 2024 May 17;10(20):eadk9076. doi: 10.1126/sciadv.adk9076. Epub 2024 May 15. Sci Adv. 2024. PMID: 38748792 Free PMC article.
The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics.
Llerena Schiffmacher DA, Lee SH, Kliza KW, Theil AF, Akita M, Helfricht A, Bezstarosti K, Gonzalo-Hansen C, van Attikum H, Verlaan-de Vries M, Vertegaal ACO, Hoeijmakers JHJ, Marteijn JA, Lans H, Demmers JAA, Vermeulen M, Sixma TK, Ogi T, Vermeulen W, Pines A. Llerena Schiffmacher DA, et al. Among authors: demmers jaa. Nat Commun. 2024 Jul 29;15(1):6374. doi: 10.1038/s41467-024-50584-7. Nat Commun. 2024. PMID: 39075067 Free PMC article.
Matrix Metalloproteinase-7 in Urinary Extracellular Vesicles Identifies Rapid Disease Progression in Autosomal Dominant Polycystic Kidney Disease.
van Heugten MH, Blijdorp CJ, Arjune S, van Willigenburg H, Bezstarosti K, Demmers JAA, Musterd-Bhaggoe U, Meijer E, Gansevoort RT, Zietse R, Hayat S, Kramann R, Müller RU, Salih M, Hoorn EJ; DIPAK Consortium. van Heugten MH, et al. Among authors: demmers jaa. J Am Soc Nephrol. 2024 Mar 1;35(3):321-334. doi: 10.1681/ASN.0000000000000277. Epub 2023 Dec 11. J Am Soc Nephrol. 2024. PMID: 38073039 Free PMC article.
Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.
Geijer ME, Zhou D, Selvam K, Steurer B, Mukherjee C, Evers B, Cugusi S, van Toorn M, van der Woude M, Janssens RC, Kok YP, Gong W, Raams A, Lo CSY, Lebbink JHG, Geverts B, Plummer DA, Bezstarosti K, Theil AF, Mitter R, Houtsmuller AB, Vermeulen W, Demmers JAA, Li S, van Vugt MATM, Lans H, Bernards R, Svejstrup JQ, Ray Chaudhuri A, Wyrick JJ, Marteijn JA. Geijer ME, et al. Among authors: demmers jaa. Nat Cell Biol. 2021 Jun;23(6):608-619. doi: 10.1038/s41556-021-00692-z. Epub 2021 Jun 9. Nat Cell Biol. 2021. PMID: 34108662 Free PMC article.
STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment.
Ramadhin AR, Lee SH, Zhou D, Salmazo A, Gonzalo-Hansen C, van Sluis M, Blom CMA, Janssens RC, Raams A, Dekkers D, Bezstarosti K, Slade D, Vermeulen W, Pines A, Demmers JAA, Bernecky C, Sixma TK, Marteijn JA. Ramadhin AR, et al. Among authors: demmers jaa. Mol Cell. 2024 Dec 19;84(24):4740-4757.e12. doi: 10.1016/j.molcel.2024.10.030. Epub 2024 Nov 14. Mol Cell. 2024. PMID: 39547223 Free article.
99 results