Jiannan Chen - Search Results

Year	Number of Results
2006	1
2009	1
2010	3
2011	4
2012	4
2013	8
2014	5
2015	5
2016	8
2017	12
2018	12
2019	13
2020	9
2021	21
2022	23
2023	18
2024	20
2025	33
2026	16

1

Coptisine protects against hyperuricemic nephropathy through alleviating inflammation, oxidative stress and mitochondrial apoptosis via PI3K/Akt signaling pathway.

Liu Y, Gong S, Li K, Wu G, Zheng X, Zheng J, Lu X, Zhang L, Li J, Su Z, Liu Y, Xie J, Chen J, Li Y. Liu Y, et al. Among authors: chen j. Biomed Pharmacother. 2022 Dec;156:113941. doi: 10.1016/j.biopha.2022.113941. Epub 2022 Nov 2. Biomed Pharmacother. 2022. PMID: 36411660 Free article.

2

UHRF1 restricts HCoV-229E infection through epigenetic silencing of the viral receptor APN.

Wang P, Wang Z, Feng F, Yin L, Zhang Y, Gao Z, Chen J, Zhang P, Yuan S, Ding Q, Hong Y, Song Y, Li C, Zhao J, Zhang R. Wang P, et al. Among authors: chen j. Nat Commun. 2025 Nov 18;16(1):10085. doi: 10.1038/s41467-025-64977-9. Nat Commun. 2025. PMID: 41253770 Free PMC article.

3

Development of a replication-defective mpox virus platform for fundamental and therapeutic research.

Chen J, Hu L, Vernuccio R, Shi N, Tian J, Zhang Y, Tian S, Cao X, Ha Z, Lu J, Battini L, Raynal B, Haouz A, Xue J, Cai Q, Zhao Y, Lu Y, Smith GL, Xie Y, Lu H, Guardado-Calvo P, Zhang P, Zhang R. Chen J, et al. Nat Commun. 2025 Dec 15;17(1):798. doi: 10.1038/s41467-025-67487-w. Nat Commun. 2025. PMID: 41397984 Free PMC article.

4

Targeting the DNA damage response enhances CD70 CAR-T cell therapy for renal carcinoma by activating the cGAS-STING pathway.

Ji F, Zhang F, Zhang M, Long K, Xia M, Lu F, Li E, Chen J, Li J, Chen Z, Jing L, Jia S, Yang R, Hu Z, Guo Z. Ji F, et al. Among authors: chen j. J Hematol Oncol. 2021 Sep 23;14(1):152. doi: 10.1186/s13045-021-01168-1. J Hematol Oncol. 2021. PMID: 34556152 Free PMC article.

5

DAZAP2 functions as a pan-coronavirus restriction factor by inhibiting viral entry and genomic replication.

Feng F, Chen J, Li R, Zhu Y, Ma Y, Wang Z, Wang Y, Gao Z, Yang L, Yu Y, Liu Y, Sun Y, Liao Y, Huang X, Zhang Q, Huang Y, Qiu L, Wu J, Zhao J, Liu C, Ding Q, Xie Y, Yuan Z, Hong Y, Zhang P, Sun J, Zhao J, Zhang R. Feng F, et al. Among authors: chen j. mBio. 2025 Sep 10;16(9):e0038525. doi: 10.1128/mbio.00385-25. Epub 2025 Aug 20. mBio. 2025. PMID: 40833112 Free PMC article.

6

Glutamine-driven metabolic reprogramming promotes CAR-T cell function through mTOR-SREBP2 mediated HMGCS1 upregulation in ovarian cancer.

Chen J, Zhao L, Li W, Wang S, Li J, Lv Z, Zhao Y, Liang J, Hu Z, Pan F, He L, Gu L, Guo Z. Chen J, et al. J Transl Med. 2025 Jul 17;23(1):803. doi: 10.1186/s12967-025-06853-0. J Transl Med. 2025. PMID: 40676647 Free PMC article. Clinical Trial.

7

Rapid generation of HCoV-229E and HCoV-OC43 reporter viruses and replicons for antiviral research.

Zhang Y, Chen J, Feng H, Yang L, Hu L, Gao Y, Wang Z, Feng F, Zhao J, Zhang P, Zhang R. Zhang Y, et al. Among authors: chen j. Front Cell Infect Microbiol. 2025 Jul 22;15:1614369. doi: 10.3389/fcimb.2025.1614369. eCollection 2025. Front Cell Infect Microbiol. 2025. PMID: 40766843 Free PMC article.

8

Microbiota-derived butyrate potentiates MSLN CAR-T cell therapy by metabolic reprogramming and extracellular matrix remodeling.

Chen J, Li W, Yang L, Li J, Wang S, Chen Z, Xu S, Wen M, Liang J, Hu Z, Pan F, He L, Gu L, Wang Z, Chen H, Guo Z. Chen J, et al. Biomed Pharmacother. 2025 Nov;192:118560. doi: 10.1016/j.biopha.2025.118560. Epub 2025 Sep 17. Biomed Pharmacother. 2025. PMID: 40967080 Free article.

9

Brusatol ameliorates irinotecan-induced delayed diarrhea via inhibition of the cGAS-STING pathway and modulation of intestinal flora.

Lai Z, Zhang Y, Huang W, Wang J, Liu C, Ren M, Huang X, Chen J, Xie J, Chen B, Lai Z, Xie Y. Lai Z, et al. Among authors: chen j. Phytomedicine. 2025 Sep;145:157071. doi: 10.1016/j.phymed.2025.157071. Epub 2025 Jul 11. Phytomedicine. 2025. PMID: 40684488

10

Sodium valproate drives propionylation-mediated epigenetic reprogramming to enhance mesothelin CAR-T cell therapy in solid tumors.

Chen J, Li W, Wang S, Li J, Zhao L, Ao X, Wang W, Zhu L, Rao H, Xu S, Wen M, Hu Z, Pan F, He L, Gu L, Fang W, Xu S, Liang J, Zhao P, Chen H, Guo Z. Chen J, et al. Mol Ther. 2026 Mar 4;34(3):1448-1464. doi: 10.1016/j.ymthe.2025.12.021. Epub 2025 Dec 11. Mol Ther. 2026. PMID: 41383012 Free article.

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