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2015 1
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Page 1
Discovery of spirooxadiazoline oxindoles with dual-stage antimalarial activity.
Lopes EA, Mestre R, Fontinha D, Legac J, Pei JV, Sanches-Vaz M, Mori M, Lehane AM, Rosenthal PJ, Prudêncio M, Santos MMM. Lopes EA, et al. Among authors: pei jv. Eur J Med Chem. 2022 Jun 5;236:114324. doi: 10.1016/j.ejmech.2022.114324. Epub 2022 Mar 28. Eur J Med Chem. 2022. PMID: 35390711
A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin.
Qiu D, Pei JV, Rosling JEO, Thathy V, Li D, Xue Y, Tanner JD, Penington JS, Aw YTV, Aw JYH, Xu G, Tripathi AK, Gnadig NF, Yeo T, Fairhurst KJ, Stokes BH, Murithi JM, Kümpornsin K, Hasemer H, Dennis ASM, Ridgway MC, Schmitt EK, Straimer J, Papenfuss AT, Lee MCS, Corry B, Sinnis P, Fidock DA, van Dooren GG, Kirk K, Lehane AM. Qiu D, et al. Among authors: pei jv. Nat Commun. 2022 Sep 30;13(1):5746. doi: 10.1038/s41467-022-33403-9. Nat Commun. 2022. PMID: 36180431 Free PMC article.
19 results