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Parasite reduction ratio one day after initiation of artemisinin-based combination therapies and its relationship with parasite clearance time in acutely malarious children.
Akano K, Ntadom G, Agomo C, Happi CT, Folarin OA, Gbotosho GO, Mokuolu O, Finomo F, Ebenebe JC, Jiya N, Ambe J, Wammanda R, Emechebe G, Basorun OK, Wewe OA, Amoo S, Ezeigwe N, Oguche S, Fatunmbi B, Sowunmi A. Akano K, et al. Infect Dis Poverty. 2018 Dec 7;7(1):122. doi: 10.1186/s40249-018-0503-7. Infect Dis Poverty. 2018. PMID: 30522524 Free PMC article. Clinical Trial.
CONCLUSIONS: PRRD1 and estimates of PCT using PRRD1 linear regression equation of PRRD1 and PCT can be used in therapeutic efficacy studies. TRIAL REGISTRATION: Pan African Clinical Trial Registration PACTR201709002064150, 1 March 2017, http://www.pactr.org....
CONCLUSIONS: PRRD1 and estimates of PCT using PRRD1 linear regression equation of PRRD1 and PCT can be used in therapeutic efficacy studies. …
Clinical illness and outcomes in Nigerian children with persistent early-appearing anaemia following initiation of artemisinin-based combination treatments of uncomplicated falciparum malaria.
Akano K, Fatunmbi B, Ntadom G, Ayede AI, Aderoyeje T, Bakre A, Alebiosu OT, Akpoborie O, Okafor C, Gbotosho GO, Folarin OA, Ebenebe JC, Ambe J, Wammanda R, Jiya N, Finomo F, Emechebe G, Mokuolu O, Agomo C, Oguche S, Happi C, Sowunmi A. Akano K, et al. Parasite. 2019;26:56. doi: 10.1051/parasite/2019058. Epub 2019 Sep 13. Parasite. 2019. PMID: 31516119 Free PMC article.
PEAA or its progression to LAA may have implications for case and community management of anaemia and for anaemia control efforts in sub-Saharan Africa where ACTs have become first-line antimalarials. Trial registration: Pan Africa Clinical Trial Registration PACTR20170900 …
PEAA or its progression to LAA may have implications for case and community management of anaemia and for anaemia control efforts in sub-Sah …
Declining responsiveness of childhood Plasmodium falciparum infections to artemisinin-based combination treatments ten years following deployment as first-line antimalarials in Nigeria.
Sowunmi A, Ntadom G, Akano K, Ibironke FO, Ayede AI, Agomo C, Folarin OA, Gbotosho GO, Happi C, Oguche S, Okafor HU, Meremikwu M, Agomo P, Ogala W, Watila I, Mokuolu O, Finomo F, Ebenebe JC, Jiya N, Ambe J, Wammanda R, Emechebe G, Oyibo W, Useh F, Aderoyeje T, Dokunmu TM, Alebiosu OT, Amoo S, Basorun OK, Wewe OA, Okafor C, Akpoborie O, Fatunmbi B, Adewoye EO, Ezeigwe NM, Oduola A. Sowunmi A, et al. Infect Dis Poverty. 2019 Aug 6;8(1):69. doi: 10.1186/s40249-019-0577-x. Infect Dis Poverty. 2019. PMID: 31383040 Free PMC article.
CONCLUSIONS: These data indicate declining parasitological responses through time to the two ACTs may be due to emergence of parasites with reduced susceptibility or decrease in immunity to the infections in these children. TRIAL REGISTRATION: Pan African Clinical Trial Re …
CONCLUSIONS: These data indicate declining parasitological responses through time to the two ACTs may be due to emergence of parasites with …
Factors contributing to anaemia after uncomplicated falciparum malaria in under five year-old Nigerian children ten years following adoption of artemisinin-based combination therapies as first-line antimalarials.
Sowunmi A, Fatunmbi B, Akano K, Wewe OA, Agomo C, Finomo F, Ebenebe J, Jiya N, Ambe J, Wammanda R, Ntadom G, Mokuolu O, Emechebe G, Ezeigwe N, Ayede AI, Adewoye EO, Gbotosho GO, Folarin OA, Happi CT, Oguche S, Oyibo WA, Useh F. Sowunmi A, et al. BMC Infect Dis. 2017 Dec 19;17(1):781. doi: 10.1186/s12879-017-2876-9. BMC Infect Dis. 2017. PMID: 29258448 Free PMC article.
CONCLUSION: After ten years of adoption of ACTs, anaemia is common pre-and early post-treatment, falls in haematocrit attributable to a single infection is high, and DAFH >4% is common and significantly lower in anaemic compared to non-anaemic Nigerian children. TRIAL REGISTRA …
CONCLUSION: After ten years of adoption of ACTs, anaemia is common pre-and early post-treatment, falls in haematocrit attributable to a sing …