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212 results

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Page 1
Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines.
Krawczyk PS, Mazur M, Orzeł W, Gewartowska O, Jeleń S, Antczak W, Kasztelan K, Brouze A, Matylla-Kulińska K, Gumińska N, Tarkowski B, Owczarek EP, Affek K, Turowski P, Tudek A, Sroka M, Śpiewla T, Kusio-Kobiałka M, Wesołowska A, Nowis D, Golab J, Kowalska J, Jemielity J, Dziembowski A, Mroczek S. Krawczyk PS, et al. Among authors: kowalska j. Nature. 2025 May;641(8064):984-992. doi: 10.1038/s41586-025-08842-1. Epub 2025 Apr 16. Nature. 2025. PMID: 40240603 Free PMC article.
Trinucleotide cap analogs with triphosphate chain modifications: synthesis, properties, and evaluation as mRNA capping reagents.
Warminski M, Depaix A, Ziemkiewicz K, Spiewla T, Zuberek J, Drazkowska K, Kedzierska H, Popielec A, Baranowski MR, Sklucka M, Bednarczyk M, Smietanski M, Wolosewicz K, Majewski B, Serwa RA, Nowis D, Golab J, Kowalska J, Jemielity J. Warminski M, et al. Among authors: kowalska j. Nucleic Acids Res. 2024 Oct 14;52(18):10788-10809. doi: 10.1093/nar/gkae763. Nucleic Acids Res. 2024. PMID: 39248095 Free PMC article.
2'-O-Methylation of the second transcribed nucleotide within the mRNA 5' cap impacts the protein production level in a cell-specific manner and contributes to RNA immune evasion.
Drazkowska K, Tomecki R, Warminski M, Baran N, Cysewski D, Depaix A, Kasprzyk R, Kowalska J, Jemielity J, Sikorski PJ. Drazkowska K, et al. Among authors: kowalska j. Nucleic Acids Res. 2022 Sep 9;50(16):9051-9071. doi: 10.1093/nar/gkac722. Nucleic Acids Res. 2022. PMID: 36018811 Free PMC article.
Potential therapeutic applications of RNA cap analogs.
Ziemniak M, Strenkowska M, Kowalska J, Jemielity J. Ziemniak M, et al. Among authors: kowalska j. Future Med Chem. 2013 Jun;5(10):1141-72. doi: 10.4155/fmc.13.96. Future Med Chem. 2013. PMID: 23795970 Review.
Synthetic mRNAs with superior translation and stability properties.
Grudzien-Nogalska E, Kowalska J, Su W, Kuhn AN, Slepenkov SV, Darzynkiewicz E, Sahin U, Jemielity J, Rhoads RE. Grudzien-Nogalska E, et al. Among authors: kowalska j. Methods Mol Biol. 2013;969:55-72. doi: 10.1007/978-1-62703-260-5_4. Methods Mol Biol. 2013. PMID: 23296927 Review.
212 results