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Massively parallel characterization of CYP2C9 variant enzyme activity and abundance.

Amorosi CJ, Chiasson MA, McDonald MG, Wong LH, Sitko KA, Boyle G, Kowalski JP, Rettie AE, Fowler DM, Dunham MJ. Amorosi CJ, et al. Among authors: kowalski jp. Am J Hum Genet. 2021 Sep 2;108(9):1735-1751. doi: 10.1016/j.ajhg.2021.07.001. Epub 2021 Jul 26. Am J Hum Genet. 2021. PMID: 34314704 Free PMC article.

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Chemical sterilization of allograft dermal tissues.

Phipps A, Vaynshteyn E, Kowalski JB, Ngo MD, Merritt K, Osborne J, Chnari E. Phipps A, et al. Among authors: kowalski jb. Cell Tissue Bank. 2017 Dec;18(4):573-584. doi: 10.1007/s10561-017-9647-0. Epub 2017 Aug 10. Cell Tissue Bank. 2017. PMID: 28799106

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Genetic modification of hematopoietic stem cells as a therapy for HIV/AIDS.

Younan P, Kowalski J, Kiem HP. Younan P, et al. Among authors: kowalski j. Viruses. 2013 Nov 28;5(12):2946-62. doi: 10.3390/v5122946. Viruses. 2013. PMID: 24287598 Free PMC article. Review.

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Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol.

Teitelbaum AM, McDonald MG, Kowalski JP, Parkinson OT, Scian M, Whittington D, Roellecke K, Hanenberg H, Wiek C, Rettie AE. Teitelbaum AM, et al. Among authors: kowalski jp. J Pharmacol Exp Ther. 2019 Feb;368(2):308-316. doi: 10.1124/jpet.118.249771. Epub 2018 Nov 8. J Pharmacol Exp Ther. 2019. PMID: 30409834 Free PMC article.

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Genetically modified hematopoietic stem cell transplantation for HIV-1-infected patients: can we achieve a cure?

Younan P, Kowalski J, Kiem HP. Younan P, et al. Among authors: kowalski j. Mol Ther. 2014 Feb;22(2):257-264. doi: 10.1038/mt.2013.264. Epub 2013 Nov 13. Mol Ther. 2014. PMID: 24220323 Free PMC article. Review.

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Pharmacokinetics, metabolism and off-target effects in the rat of 8-[(1H- benzotriazol-1-yl)amino]octanoic acid, a selective inhibitor of human cytochrome P450 4Z1: β-oxidation as a potential augmenting pathway for inhibition.

Kowalski JP, Pelletier RD, McDonald MG, Kelly EJ, Rettie AE. Kowalski JP, et al. Xenobiotica. 2021 Aug;51(8):901-915. doi: 10.1080/00498254.2021.1930281. Epub 2021 Jun 11. Xenobiotica. 2021. PMID: 33993844

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Design and Characterization of the First Selective and Potent Mechanism-Based Inhibitor of Cytochrome P450 4Z1.

Kowalski JP, McDonald MG, Pelletier RD, Hanenberg H, Wiek C, Rettie AE. Kowalski JP, et al. J Med Chem. 2020 May 14;63(9):4824-4836. doi: 10.1021/acs.jmedchem.0c00101. Epub 2020 Apr 30. J Med Chem. 2020. PMID: 32302132

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Novel insights into oxidation of fatty acids and fatty alcohols by cytochrome P450 monooxygenase CYP4B1.

Thesseling FA, Hutter MC, Wiek C, Kowalski JP, Rettie AE, Girhard M. Thesseling FA, et al. Among authors: kowalski jp. Arch Biochem Biophys. 2020 Jan 15;679:108216. doi: 10.1016/j.abb.2019.108216. Epub 2019 Dec 1. Arch Biochem Biophys. 2020. PMID: 31801692 Free PMC article.

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Heterologous Expression and Functional Characterization of Novel CYP2C9 Variants Identified in the Alaska Native People.

McDonald MG, Henderson LM, Ray S, Yeung CK, Johnson AL, Kowalski JP, Hanenberg H, Wiek C, Thummel KE, Rettie AE. McDonald MG, et al. Among authors: kowalski jp. J Pharmacol Exp Ther. 2020 Aug;374(2):233-240. doi: 10.1124/jpet.120.265850. Epub 2020 May 18. J Pharmacol Exp Ther. 2020. PMID: 32423989 Free PMC article.

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Setting Standards: Extending the VD_max Approach: AAMI TIR76 and Its Web-Based Calculation Tool.

Kowalski JB. Kowalski JB. Biomed Instrum Technol. 2019 May/Jun;53(3):232-236. doi: 10.2345/0899-8205-53.3.232. Biomed Instrum Technol. 2019. PMID: 31162961 No abstract available.

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