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2018 3
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2020 3
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Page 1
Bacterial Metabolism and Antibiotic Efficacy.
Stokes JM, Lopatkin AJ, Lobritz MA, Collins JJ. Stokes JM, et al. Cell Metab. 2019 Aug 6;30(2):251-259. doi: 10.1016/j.cmet.2019.06.009. Epub 2019 Jul 3. Cell Metab. 2019. PMID: 31279676 Free PMC article. Review.
A Deep Learning Approach to Antibiotic Discovery.
Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackermann Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, Church GM, Brown ED, Jaakkola TS, Barzilay R, Collins JJ. Stokes JM, et al. Cell. 2020 Feb 20;180(4):688-702.e13. doi: 10.1016/j.cell.2020.01.021. Cell. 2020. PMID: 32084340
Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate.
Lopatkin AJ, Stokes JM, Zheng EJ, Yang JH, Takahashi MK, You L, Collins JJ. Lopatkin AJ, et al. Among authors: stokes jm. Nat Microbiol. 2019 Dec;4(12):2109-2117. doi: 10.1038/s41564-019-0536-0. Epub 2019 Aug 26. Nat Microbiol. 2019. PMID: 31451773
A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria.
Stokes JM, Gutierrez A, Lopatkin AJ, Andrews IW, French S, Matic I, Brown ED, Collins JJ. Stokes JM, et al. Nat Methods. 2019 Apr;16(4):303-306. doi: 10.1038/s41592-019-0333-y. Epub 2019 Mar 11. Nat Methods. 2019. PMID: 30858599
Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance.
Stokes JM, MacNair CR, Ilyas B, French S, Côté JP, Bouwman C, Farha MA, Sieron AO, Whitfield C, Coombes BK, Brown ED. Stokes JM, et al. Nat Microbiol. 2017 Mar 6;2:17028. doi: 10.1038/nmicrobiol.2017.28. Nat Microbiol. 2017. PMID: 28263303 Free PMC article.
A Deep Learning Approach to Antibiotic Discovery.
Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackermann Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, Church GM, Brown ED, Jaakkola TS, Barzilay R, Collins JJ. Stokes JM, et al. Cell. 2020 Apr 16;181(2):475-483. doi: 10.1016/j.cell.2020.04.001. Cell. 2020. PMID: 32302574 No abstract available.
Our Evolving Understanding of the Mechanism of Quinolones.
Gutierrez A, Stokes JM, Matic I. Gutierrez A, et al. Among authors: stokes jm. Antibiotics (Basel). 2018 Apr 8;7(2):32. doi: 10.3390/antibiotics7020032. Antibiotics (Basel). 2018. PMID: 29642475 Free PMC article. Review.
Bicarbonate Alters Bacterial Susceptibility to Antibiotics by Targeting the Proton Motive Force.
Farha MA, French S, Stokes JM, Brown ED. Farha MA, et al. Among authors: stokes jm. ACS Infect Dis. 2018 Mar 9;4(3):382-390. doi: 10.1021/acsinfecdis.7b00194. Epub 2018 Jan 4. ACS Infect Dis. 2018. PMID: 29264917
Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics.
MacNair CR, Stokes JM, Carfrae LA, Fiebig-Comyn AA, Coombes BK, Mulvey MR, Brown ED. MacNair CR, et al. Among authors: stokes jm. Nat Commun. 2018 Jan 31;9(1):458. doi: 10.1038/s41467-018-02875-z. Nat Commun. 2018. PMID: 29386620 Free PMC article.
Chemical inhibition of bacterial ribosome biogenesis shows efficacy in a worm infection model.
Stokes JM, Selin C, Cardona ST, Brown ED. Stokes JM, et al. Antimicrob Agents Chemother. 2015 May;59(5):2918-20. doi: 10.1128/AAC.04690-14. Epub 2015 Feb 23. Antimicrob Agents Chemother. 2015. PMID: 25712357 Free PMC article.
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