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2015 1
2016 2
2017 4
2018 3
2019 5
2020 5
2021 2
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Page 1
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
Pujols J, Peña-Díaz S, Lázaro DF, Peccati F, Pinheiro F, González D, Carija A, Navarro S, Conde-Giménez M, García J, Guardiola S, Giralt E, Salvatella X, Sancho J, Sodupe M, Outeiro TF, Dalfó E, Ventura S. Pujols J, et al. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10481-10486. doi: 10.1073/pnas.1804198115. Epub 2018 Sep 24. Proc Natl Acad Sci U S A. 2018. PMID: 30249646 Free PMC article.
Chemical Chaperones as Novel Drugs for Parkinson's Disease.
Pujols J, Peña-Díaz S, Pallarès I, Ventura S. Pujols J, et al. Trends Mol Med. 2020 Apr;26(4):408-421. doi: 10.1016/j.molmed.2020.01.005. Epub 2020 Feb 12. Trends Mol Med. 2020. PMID: 32277934 Review.
DisProt: intrinsic protein disorder annotation in 2020.
Hatos A, Hajdu-Soltész B, Monzon AM, Palopoli N, Álvarez L, Aykac-Fas B, Bassot C, Benítez GI, Bevilacqua M, Chasapi A, Chemes L, Davey NE, Davidović R, Dunker AK, Elofsson A, Gobeill J, Foutel NSG, Sudha G, Guharoy M, Horvath T, Iglesias V, Kajava AV, Kovacs OP, Lamb J, Lambrughi M, Lazar T, Leclercq JY, Leonardi E, Macedo-Ribeiro S, Macossay-Castillo M, Maiani E, Manso JA, Marino-Buslje C, Martínez-Pérez E, Mészáros B, Mičetić I, Minervini G, Murvai N, Necci M, Ouzounis CA, Pajkos M, Paladin L, Pancsa R, Papaleo E, Parisi G, Pasche E, Barbosa Pereira PJ, Promponas VJ, Pujols J, Quaglia F, Ruch P, Salvatore M, Schad E, Szabo B, Szaniszló T, Tamana S, Tantos A, Veljkovic N, Ventura S, Vranken W, Dosztányi Z, Tompa P, Tosatto SCE, Piovesan D. Hatos A, et al. Among authors: pujols j. Nucleic Acids Res. 2020 Jan 8;48(D1):D269-D276. doi: 10.1093/nar/gkz975. Nucleic Acids Res. 2020. PMID: 31713636 Free PMC article.
Inhibition of α-Synuclein Aggregation and Mature Fibril Disassembling With a Minimalistic Compound, ZPDm.
Peña-Díaz S, Pujols J, Pinheiro F, Santos J, Pallarés I, Navarro S, Conde-Gimenez M, García J, Salvatella X, Dalfó E, Sancho J, Ventura S. Peña-Díaz S, et al. Among authors: pujols j. Front Bioeng Biotechnol. 2020 Oct 16;8:588947. doi: 10.3389/fbioe.2020.588947. eCollection 2020. Front Bioeng Biotechnol. 2020. PMID: 33178678 Free PMC article.
Disulfide driven folding for a conditionally disordered protein.
Fraga H, Pujols J, Gil-Garcia M, Roque A, Bernardo-Seisdedos G, Santambrogio C, Bech-Serra JJ, Canals F, Bernadó P, Grandori R, Millet O, Ventura S. Fraga H, et al. Among authors: pujols j. Sci Rep. 2017 Dec 5;7(1):16994. doi: 10.1038/s41598-017-17259-4. Sci Rep. 2017. PMID: 29208936 Free PMC article.
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