Ultra-High-Dose-Rate FLASH Irradiation Limits Reactive Gliosis in the Brain.
Montay-Gruel P, Markarian M, Allen BD, Baddour JD, Giedzinski E, Jorge PG, Petit B, Bailat C, Vozenin MC, Limoli C, Acharya MM.
Montay-Gruel P, et al.
Radiat Res. 2020 Dec 1;194(6):636-645. doi: 10.1667/RADE-20-00067.1.
Radiat Res. 2020.
PMID: 32853387
Free PMC article.
Interestingly, while FLASH-RT did not induce astrogliosis and TLR4, the expression level of complement C1q and C3 were found to be elevated in both FLASH and CONV irradiation modalities compared to the control. ...
Interestingly, while FLASH-RT did not induce astrogliosis and TLR4, the expression level of complement C1q and C3 were found to be el …