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Risk Factors Associated with Intensive Care Admission in Children with Severe Acute Respiratory Syndrome Coronavirus 2-Related Multisystem Inflammatory Syndrome (MIS-C) in Latin America: A Multicenter Observational Study of the REKAMLATINA Network.
Fernández-Sarmiento J, Acevedo L, Niño-Serna LF, Boza R, García-Silva J, Yock-Corrales A, Yamazaki-Nakashimada MA, Faugier-Fuentes E, Del Águila O, Camacho-Moreno G, Estripeaut D, Gutiérrez IF, Luciani K, Espada G, Álvarez-Olmos MI, Pérez-Camacho P, Duarte-Passos S, Cervi MC, Cantillano EM, Llamas-Guillén BA, Saltigeral-Simental P, Criales J, Chacon-Cruz E, García-Domínguez M, Aguilar KLB, Jarovsky D, Ivankovich-Escoto G, Tremoulet AH, Ulloa-Gutierrez R; REKAMLATINA-3 Study Group Investigators 32. Fernández-Sarmiento J, et al. J Intensive Care Med. 2024 Aug;39(8):785-793. doi: 10.1177/08850666241233189. Epub 2024 Feb 28. J Intensive Care Med. 2024. PMID: 38414438

These patients had more myocardial dysfunction (20% vs 4%; P < 0.01) with no difference in the frequency of coronary abnormalities (P = 0.77) when compared to general ward subjects. Of the children in the PICU, 83.4% (494/589) required vasoactive drugs, and 43.4%

…

These patients had more myocardial dysfunction (20% vs 4%; P < 0.01) with no difference in the frequency of coronary abnormalities

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Multisystem inflammatory syndrome in children across 16 Latin American countries: A multicenter study from the REKAMLATINA Network.
García-Silva J, Ulloa-Gutierrez R, Ivankovich-Escoto G, Yamazaki-Nakashimada MA, Faugier-Fuentes E, Del Águila O, Camacho-Moreno G, Estripeaut D, Gutiérrez IF, Castillo-Bustamante D, Luciani K, Fabi M, Espada G, Álvarez-Olmos MI, Silfa C, Pérez-Camacho P, Duarte-Passos S, Cervi MC, Martínez-Ramírez RO, Cantillano EM, Llamas-Guillén BA, Velásquez-Méndez M, Saltigeral-Simental P, Criales J, Fernández-Sarmiento J, Chacon-Cruz E, García-Domínguez M, Aguilar KLB, Villarreal-Treviño AV, Tremoulet AH; REKAMLATINA-3 MIS-C Study Group Investigators. García-Silva J, et al. IJID Reg. 2024 Aug 3;12:100419. doi: 10.1016/j.ijregi.2024.100419. eCollection 2024 Sep. IJID Reg. 2024. PMID: 39295841 Free PMC article.
The death rate attributed to MIS-C was 4.88%, with a rate of 3.39% for those initially diagnosed with MIS-C and 8.85% for those whose admission diagnosis was not MIS-C (P <0.001, odds ratio 2.76, 95% confidence interval 1.6-4.6). CONCLUSIONS: One of the most significant …
The death rate attributed to MIS-C was 4.88%, with a rate of 3.39% for those initially diagnosed with MIS-C and 8.85% for those whose admiss …